hepatic lipase (LIPC)
Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene The LOCAT Study Invsestigators
... the hepatic lipase (HL) gene ( LIPC ) and variation in posthep- arin HL activity and fasting serum lipoproteins were evalu- ated in 395 male Finnish coronary heart disease patients with HDL cholesterol ...
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Abnormalities in hepatic lipase in chronic renal failure: role of excess parathyroid hormone
... ter 8 h of incubation of cells from CRF-PTX and CRF-V and of their media was not different from those obtained in hepa- tocytes and their media from normal or normal-V animals. Also, the exposure of hepatocytes from ...
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Variation at the hepatic lipase and apolipoprotein AI/CIII/AIV loci is a major cause of genetically determined variation in plasma HDL cholesterol levels
... hepatic lipase and apolipoprotein AI/CIII/AIV accounted for 25 and 22%, respectively, of the total interindividual variation in plasma HDL-C ...the hepatic lipase and the apolipoprotein ...
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Positive association of the hepatic lipase gene polymorphism c.514C > T with estrogen replacement therapy response
... Background: Hepatic lipase (HL), an enzyme present in the hepatic sinusoids, is responsible for the lipolysis of lipoproteins. Human HL contains four polymorphic sites: G-250A, T-710C, A-763G, and ...
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High density lipoprotein2 Relationship of the plasma levels of this lipoprotein species to its composition, to the magnitude of postprandial lipemia, and to the activities of lipoprotein lipase and hepatic lipase
... Lipoprotein lipase (LPL) activity in postheparin plasma of 38 normolipidemic volunteers was related to the magnitude of postprandial lipemia after a fat meal, to triglyceride content of high density lipoprotein2 ...
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Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE deficient and LCAT transgenic mice
... Hepatic lipase (HL) has a well-established role in lipoprotein metabolism. However, its role in ath- erosclerosis is poorly understood. Here we demonstrate that HL deficiency raises the proathero- genic ...
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Postprandial lipemia A key for the conversion of high density lipoprotein2 into high density lipoprotein3 by hepatic lipase
... subjects, HDL2 levels ranged widely from 4.7 to 151.7 mg/dl plasma. HDL2 were isolated in the postabsorptive (pa) state and in the postprandial (pp) state, i.e., 7 h after ingestion of a standard fatty meal. In going ...
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Hepatic lipase gene therapy in hepatic lipase deficient mice Adenovirus mediated replacement of a lipolytic enzyme to the vascular endothelium
... Hepatic lipase (HL) is an endothelial-bound lipolytic en- zyme which functions as a phospholipase as well as a tri- acylglycerol hydrolase and is necessary for the metabolism of IDL and ...• hepatic ...
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Effect of heparin induced lipolysis on the distribution of apolipoprotein e among lipoprotein subclasses Studies with patients deficient in hepatic triglyceride lipase and lipoprotein lipase
... hepatic lipase or of lipoprotein lipase and compared them with normal ...familial hepatic triglyceride lipase deficiency (n = 2) differ markedly from normal in that fraction II is the ...
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Lipoprotein Metabolism during Acute Inhibition of Hepatic Triglyceride Lipase in the Cynomolgus Monkey
... enzyme hepatic triglyceride lipase was investigated in a primate model, the cynomolgus ...postheparin hepatic lipase fully inhibited cynomolgus monkey posttheparin plasma hepatic ...
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Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase–deficient mouse adipose tissue
... Endothelial lipase (EL) is a plausible candidate to provide FFAs for subsequent uptake in peripheral tissues in addition to ...LPL, hepatic lipase, and pancreatic lipase (20, ...the ...
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Anti-obesity activity of hen egg anti-lipase immunoglobulin yolk, a novel pancreatic lipase inhibitor
... To investigate the effect of anti-lipase IgY on the ab- sorption of triglyceride in the diet, we analyzed fecal lipids contents. Previous study showed that lipase inhib- ition by synthetic lipase ...
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Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormones sensitive lipase in human subcutaneous abdominal adipocytes
... [39] Iverius P-H, Brunzell JD. Relationship between lipoprotein lipase activity and plasma sex steroid levels in obese women. J Clin Invest 1988; 82: 1106-1112. [40] Price TM, O'Brien SN, Welter BH, George R, ...
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CLINICAL USEFULNESS OF LIPASE AND AMYLASE - AN UPDATE
... serum lipase and amylase of ...serum lipase and amylase, which were not predictive of an event of subsequent acute pancreatitis [2] ...pancreatic lipase and amylase enzymes, and changes in pancreatic ...
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Major Hepatic Resection in Hepatic Hydatidosis
... Surgical methods to obliterate the cyst cavity can be separated as conservative (simple drainage, unroofing, and omentoplasty) or radical procedure (partial cystec- tomy, pericystectomy and hepatic resections). ...
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Production and Purification of a New Inhibitor of Pancreatic Lipase andHormone Sensitive Lipase from Soil Actinomycetes
... The lipase inhibitory activity was assessed using different lipases: Pancreatic lipase (PL),Hormone sensitive lipase(HSL)[13],Monoacylglycerol ...microbial lipase inhibitor and 200 μL of 50 mM ...
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Frozen Microemulsions for MAPLE Immobilization of Lipase
... In figure 3 optical micrographs of M-CRL2 and M-CRL3 are shown. As displayed in figure 3 (a), M-CRL2 film is formed by micrometric clusters and crystalline inclusions, some of which are evidenced by white circles. These ...
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Regulation of lipoprotein lipase in the diabetic rat
... Diabetes mellitus is associated with a reduction of lipoprotein lipase (LPL) activity and development of hypertriglyceridemia. In the current experiments the mechanisms involved in the regulation of LPL have been ...
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Variations in Hepatic Angiosis and Their Significance in Hepatic Pathology
... in hepatic perfusion ...of hepatic perfusion with the second giving a simpler ...of hepatic perfusion differs from study to study, indicating how complex hepatic anatomy ...
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Changes in lipoprotein lipase and endothelial lipase mass in familial hypercholesterolemia during three-drug lipid-lowering combination therapy
... Categorical variables are expressed as percentages. Con- tinuous variables with a normal distribution are shown as means (± SD), and those with a skewed distribution are shown as medians (interquartile [IQR]). The ...
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