Hepatic metabolism
Epigenomic and Transcriptional Regulation of Hepatic Metabolism by REV-ERB and Hdac3
... 126 liver clock and liver metabolism. Last, REV-ERB and REV-ERB bind to the Rev-erb promoter, but not the Rev-erb promoter, and this difference hints that REV-ERB and REV-ERB are not equal in the core clock ...
165
HEPATIC METABOLISM OF CHOLESTEROL IN EXPERIMENTAL NEPHROSIS IN RATS
... That the hypercholesteremia present 24 hours after AKS injection Group 3 was actually induced by the AKS, rather than being due to any AKS-induced delay in plasma clearance of the inject[r] ...
9
HEPATIC METABOLISM OF PHENYLALANINE DURING DEVELOPMENT
... Supplementing inactive soluble fractions of livers from fetal rats, rabbits and pigs with adult rat liver fractions shows quite conclusively that, in each case, the addition of Fraction [r] ...
9
Hepatic metabolism of free fatty acids in normal and diabetic dogs
... and hepatic vein and infused intravenously with palmitate-1- 14 C were used to estimate uptake of free fatty acids in liver and their conversion to major metabolic products secreted into hepatic venous ...
12
Intervention in hepatic lipid metabolism : implications for atherosclerosis progression and regression
... the hepatic sinusoids, while Kupffer cells are found in the sinusoidal lumen on top of or between endothelial cells ...of hepatic resident ...the hepatic distribution of LDL and significant ...
147
Species differences in the metabolism of pyrethroid pesticides : potential implications for human health risk assessment
... of metabolism of a pyrethroid directly influenced its toxic ...that hepatic metabolism of pyrethroids drives blood and brain concentrations thus influencing their toxic ...the hepatic ...
190
Protection against LPS induced cartilage inflammation and degradation provided by a biological extract of Mentha spicata
... simulate hepatic metabolism of RA, liver microsomes from rat (male) (Sigma Aldrich, Mississauga ON Canada) were added to a final concentration of ...
11
Results: Abnormality in blood pH was noted in 35(70%) patients. Alkalosis was commonest finding (40%)
... impaired hepatic metabolism in advanced liver disease) that may directly stimulate ventilation by the activation of progesterone receptors in the central nervous system leading to ...to hepatic ...
6
Lipopolysaccharide significantly influences the hepatic triglyceride metabolism in growing pigs
... TG metabolism in mice and chicken [11, ...TG metabolism, if changed, is correlated with the GR in the liver of growing pigs is also ...TG metabolism in the liver of growing pigs after the injection ...
10
Encephalopathy of Reye's Syndrome: A Review of Pathogenetic Hypotheses
... are several possible sources of hyperlactatemia in Reye’s syndrome: (1) excess production by brain7 and muscle, (2) impaired hepatic metabolism via gluconeogenesis or the tnicarboxylic a[r] ...
13
Oral opioid metabolism and pharmacogenetics
... codeine, hepatic metabolism is necessary for their bioactivation into more potent ...analgesics. Hepatic biotransformation generally occurs as Phase I and Phase II ...the metabolism and ...
8
Formulation and Characterization of Cefixime Phytosomes for Oral Drug Delivery
... Cefixime is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. Cefixime is highly stable in the presence of ...
9
Hepatic zonation of carbon and nitrogen fluxes derived from glutamine and ammonia transformations
... the hepatic artery in retrograde perfusion [16] and which has been successfully used for investigating hepatic zonation without significant alterations of the liver structure ...
11
“Design and Evaluation of Mucoadhesive Buccal Patch of Ramipril” by Anjana Anil, Preethi Sudheer, India.
... Ramipril is a sparingly soluble drug with a log p value of 3.32. After oral administration, drug exhibits bioavailability of 28% due to its high first pass metabolism. The biological half life of drug is reported ...
9
Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects
... hypercholesterolemia was 53 and 59% of normal. The activity of the rate-limiting enzyme in cholesterol biosynthesis, 3-hydroxy-3-methylglutaryl coenzyme A reductase was normal; however, the total hepatic ...
9
Artemisinin Reduces Lipid Accumulation in Hepatocytes by Inhibition of CD36 Expression
... 26. Araya J, Rodrigo R, Videla LA, Thielemann L, Orellana M, Pettinelli P, et al. Increase in long-chain polyunsaturated fatty acid n−6/n−3 ratio in relation to hepatic steatosis in patients with non-alcoholic ...
8
THE METABOLISM OF ALDOSTERONE IN NORMAL SUBJECTS AND IN PATIENTS WITH HEPATIC CIRRHOSIS
... The delayed plasma disappearance of 7-H3-d-aldosterone and the altered pattern of excretion of urinary metabolites in patients with cirrhosis, therefore, is to be attributed to the prese[r] ...
10
Ethanol impairs post prandial hepatic protein metabolism
... To simulate social drinking, we compared the effects of the association of a mixed meal 632 kcal, 17% amino acids, 50% glucose, 33% lipids with a bottle of either table wine ethanol cont[r] ...
9
Effects of Karela (Bitter Melon; Momordica charantia) on genes of lipids and carbohydrates metabolism in experimental hypercholesterolemia: biochemical, molecular and histopathological study
... Metabolic syndrome has become the most prevalent worldwide epidemic diseases in recent decades. A recent national health survey conducted in mainland China re- vealed that 60 million people are obese and 200 million are ...
13
A LIVER ENZYME THAT CONJUGATES SULFOBROMOPHTHALEIN SODIUM WITH GLUTATHIONE
... The results of the present investigation disclosed three critical features of hepatic BSP metabolism; first, an enzyme is described, identified in liver, which catalyzes the conjugation [r] ...
9