hepatic stellate cells
Hepatic stellate cells: central modulators of hepatic carcinogenesis
... Hepatic stellate cells (HSC) are the major source of extracellular proteins during fibrogenesis, and may directly, or via secreted products, contribute to tumour initiation and ...
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Hepatic stellate cells contribute to progenitor cells and liver regeneration
... tor cells, which are called oval cells in rodents, could represent an intermediate stage during hepatic differentiation of stellate cells or other ...progenitor cells are small ...
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Hepatic stellate cells and parasite induced liver fibrosis
... The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well investigated over the last few years in a number of ...
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Hepatic stellate cells and parasite induced liver fibrosis
... The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well investigated over the last few years in a number of ...
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Hepatic stellate cells in liver development, regeneration, and cancer
... USA. Hepatic stellate cells are liver-specific mesenchymal cells that play vital roles in liver physiology and fibrogene- ...endothelial cells and hepatic epithelial ...that ...
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Hepatic stellate cells increase in Toxoplasma gondii infection in mice
... Another experimental study has yielded similar infor- mation, determining that HSCs are directly involved in the restoration of liver mass even in vivo [26]. Rastogi et al. [9] reported a possible dynamic role of HSCs in ...
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Roles of hepatic stellate cells in liver inflammation: a new perspective
... substances. Hepatic stellate cells (HSCs) are pericytes residing in the perisinusoidal space, between sinusoidal endothelial cells and hepatocytes, store vitamin A, and regulate sinusoidal ...
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Discovery of Aptamer Ligands for Hepatic Stellate Cells Using SELEX
... into hepatic stellate cells for the treatment of liver ...rat hepatic stellate ...the cells and induce silencing activity, but the siRNA-aptamer chimera (100 nM) exhibited a ...
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Levels of hepatic Th17 cells and regulatory T cells upregulated by hepatic stellate cells in advanced HBV related liver fibrosis
... Th17 cells and regulatory T cells were detected by flow cytometry analysis and ...how hepatic stellate cells regulate the levels of Th17 cells and regulatory T ...
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NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis
... in hepatic stellate cells (HSCs), a fibrogenic cell ...in hepatic wound-healing response in a redox- sensitive manner, as assessed by microarray ...
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synergistically increase PAI-1 expression in hepatic stellate cells of rats
... induced hepatic fibrosis is still ...primary hepatic stellate cells (HSCs): The fluids and digestives used in the present study were able to completely remove blood cells, digest ...
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HNE interacts directly with JNK isoforms in human hepatic stellate cells
... HNE has been shown to stimulate procollagen type I gene expression and synthesis in human hepatic stellate cells (hHSC) which are known to play a key role in liver fibrosis. In this study we ...
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Proliferation of hepatic stellate cells is inhibited by phosphorylation of CREB on serine 133
... activated, hepatic stellate cells have a high level of collagen type I ...Therefore, stellate cell proliferation is a critical step in hepatic ...rat stellate cells was ...
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Original Article Erythropoietin improves hepatic fibrosis via suppression of hepatic stellate cells and macrophage activation
... Hepatic stellate cells and Kupffer cells are key players in liver fibrosis [12, ...on hepatic fibro- sis, in vitro models of activation of HSCs and ...Raw264.7 cells were used ...
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Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells.
... Conclusion: These data provide evidence for EPIM and SOX9 functioning by mutual negative feedback to regulate attributes of the quiescent or activated state of HSCs. Further understanding of EPIM’s role may lead to ...
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Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis
... Amphiregulin (AR) involvement in liver fibrogenesis and hepatic stellate cells (HSC) regulation is under study. Non-alcoholic fatty liver disease (NAFLD) and its more severe form non-alcoholic ...
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The bidirectional crosstalk between metastatic uveal melanoma cells and hepatic stellate cells engenders an inflammatory microenvironment
... cancerous cells, as well as their interactions with the extracellular matrix and soluble ...primary hepatic stellate cells (Xu et ...activated stellate cells from the ...
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Activation of NLRP3 inflammasomes in mouse hepatic stellate cells during Schistosoma J. infection
... inflammasome, hepatic stellate cell, cathepsin B, Schistosoma ...in hepatic stellate cells (HSCs), as shown by a marked increase in co-localization of IL-1β with HSCs marker, ...
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DDR2 receptor promotes MMP 2–mediated proliferation and invasion by hepatic stellate cells
... of hepatic stellate cells during liver injury through mechanisms that have been ...in stellate cells activated by primary culture or in vivo during liver ...developed stellate ...
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The interplay of the Notch signaling in hepatic stellate cells and macrophages determines the fate of liver fibrogenesis
... . Hepatic stellate cells (HSCs) are considered as the major producers of fibrotic ECM during liver fibrosis, but activation of macrophages is also an essential step in the initiation of fibrogenesis ...
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