hepatitis B virus X gene
Mutations at Nucleotide 1762, 1764 and 1766 of Hepatitis B Virus X Gene in Patients with Chronic Hepatitis B and Hepatitis B-Related Cirrhosis
... with hepatitis B virus (HBV) and 350 to 400 million chronic carriers of this virus in the world ...(1,2). Hepatitis is defined as the inflammation of the liver and HBV is one of the ...
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Molecular characterization of hepatitis B virus X gene in chronic hepatitis B patients
... for virus replication, including the basal core ...the X gene may have implications in biological functions of the protein and thus, affect the evolution of the ...HBV-X gene in chronic ...
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A transcription initiation site for the hepatitis B virus X gene is directed by the promoter-binding protein.
... In contrast, the similar mutations introduced into this target sequence for X-PBP binding failed to shift the transcription start site of the CAT construct, in which the X promoter regio[r] ...
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The Hepatitis B Virus X Protein Transactivates Viral Core Gene Expression In Vivo
... the X gene in cex lineages and the absence of this ATG in ce lineages, respectively, was confirmed in represen- tatives of all lines by sequence analyses of PCR products am- plified from genomic DNA and ...
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Mutations in hepatitis B virus small <em>S</em> genes predict postoperative survival in hepatocellular carcinoma
... Abstract: Hepatitis B virus (HBV) DNA is prone to mutations due to proofreading deficiencies of HBV ...the X, precore, and core ...S gene of HBV genome in 115 HCC patients including 60 ...
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X GENE VARIABILITY AND GENOTYPING OF HEPATITIS B VIRUS (HBV) IN SUDANESE PATIENTS WITH LIVER DISEASES, KHARTOUM, SUDAN
... HBx gene mutations may have a role in the progression of liver disease from chronic infection to liver cirrhosis and/or hepatocellular ...HBx gene among hepatitis B patients, find out the ...
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The Enigmatic X Gene of Hepatitis B Virus
... HBV X cod- ing sequence as well as the HBV enhancer I region, the X gene promoter, and the HBV polyadenylation signal ...antithrombin gene regulatory sequence; none of these studies supported ...
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Impact of Hepatitis B Virus (HBV) X Gene Mutations on Hepatocellular Carcinoma Development in Chronic HBV Infection
... B was not significantly activated by triple mutations in HCC ... B signaling ... B activity was characteristically affected by the existence of HBx5 ... B activity. We found through ...
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Altered Proteolysis and Global Gene Expression in Hepatitis B Virus X Transgenic Mouse Liver
... chronic hepatitis B virus infection, but the mecha- nism has not been fully ...livers. Gene expression levels of IGFBP-1 and IGF-1 were quantified by TaqMan ...
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Study of Hepatitis B Virus Genotypes and Mutation in 1762 & 1764 Nucleotides of X Gene in Chronic HBV Patients from Golestan Province—Iran
... Study of Hepatitis B Virus Genotypes and Mutation in 1762 & 1764 Nucleotides of X Gene in Chronic HBV Patients from Golestan Province—Iran Sareh Zhand1, Ghassem Rostamian2, Alijan Tabarr[r] ...
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Hepatitis B virus x protein induces epithelial mesenchymal transition of hepatocellular carcinoma cells by regulating long non coding RNA
... All the data were presented as the mean ± SD. Student’s- test was used to compare the difference between the two groups. The relationship between the two groups was analysed by the Pearson correlation test. P < 0.05 ...
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Upregulation of MicroRNA 146a by Hepatitis B Virus X Protein Contributes to Hepatitis Development by Downregulating Complement Factor H
... HBV-induced hepatitis is ...chemical-induced hepatitis (33) and liver-specific autoantibody- mediated hepatitis ...HBV-induced hepatitis is ...with B or Bb for FIG 5 HBx-mediated ...
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A new enhancer element, ENII, identified in the X gene of hepatitis B virus.
... It functioned much better in the highly differentiated hepatoma cells but not in nonliver cells or 3977 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest A new enhancer e[r] ...
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An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein
... The gene encoding the LIM and SH3 domain protein (LASP1) was cloned two decades ago from a cDNA library of breast cancer metastases. As the first protein of a class comprising one N-terminal LIM and one C-terminal ...
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Prevalence and Clinical study of Hepatitis B in Antenatal Women
... Majority of HBV infection in children are asymptomatic versus those in adults, about 30 to 50% develop acute icteric hepatitis. Those who recover should acquire lifelong immunity. However, a subset of patients ...
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Hepatitis B surface gene 145 mutant as a minor population in hepatitis B virus carriers
... Direct sequencing showed that I/T126S [9,18,19], I/ T126V [16], Q129L [20,21], T131P [22], M133T + T140I [13,14,21,23], and S136Y [24,25] mutants were present as a predominant strain in 107 HBV carriers. All of these ...
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Hepatitis B Virus X Protein Function Requires Zinc Binding
... or X-tremeGENE HP DNA transfection reagent (Roche Diagnostics), respectively, according to the manufacturer’s ...Triton X-100, and 1% deoxycholate (IP ...
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Prevalence and trends of markers of hepatitis B virus, hepatitis C virus and human Immunodeficiency virus in Argentine blood donors
... 15. de los Angeles Pando M, Biglione MM, Toscano MF, Rey JA, Russell KL, Negrete M, Gianni S, Martinez-Peralta L, Salomon H, Sosa-Estani S, Montano SM, Olson JG, Sanchez JL, Carr JK, Avila MM: Human immunodeficiency ...
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High prevalence of HIV, HBsAg and anti HCV positivity among people who injected drugs: results of the first bio behavioral survey using respondent driven sampling in two urban areas in Mozambique
... on self-reports likely underestimate true HIV prevalence because persons with HIV are likely reluctant to disclose status due to stigma. The high refusal rate for hepatitis C testing likely underestimates the true ...
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The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.
... First, we investigated whether proteins were produced from ORF5 and ORF6 by in vitro translation of appropriate viral transcripts, searched for antibodies against the putative proteins i[r] ...
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