Hepatitis C/drug therapy
Stability analysis of an in-vivo hepatitis C dynamics model with therapy
... antiviral drug therapy is a reliable and effective therapeutic strategy that either eradicates the disease or reduces the intensity of the disease ...
20
Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus
... Despite DAAs offering a high genetic barrier to resist- ance, especially NS5B nucleos(t)ide inhibitors, there is an increasing list of mutations which are related to resistance to DAAs in clinical use, including ...
15
Pharmacogenomics of chronic hepatitis C therapy with genome-wide association studies
... In this study, we reviewed several recent GWAS findings and relevant studies for the drug efficacy of IFN in CHC patients. Although further research is necessary to study the functional mechanism underlying the ...
10
Global Stability Analysis of the Original Cellular Model of Hepatitis C Virus Infection Under Therapy
... [3] Chong, Maureen Siew Fang, Shahrill, Masitah, Crossley, Laurie and Madzvamuse, Anotida, 2015 The stability analyses of the mathematical models of hepatitis C virus infection. Modern Applied Science, 9 ...
8
Prospects for personalizing antiviral therapy for hepatitis C virus with pharmacogenetics
... of therapy indicates that predicting the outcome of therapy for HCV will require integrating the efficacies of the immunosuppressive mechanisms of a viral isolate, and then interpreting the viral resistance ...
9
Evaluation of quantitative liver function tests in HIV-positive patients under anti-retroviral therapy
... minimal drug interactions, have a high predictive value, and fi- nally, provide quick results (Jalan and Hayes 1995; Candelli, Cazzato et ...alcoholic hepatitis (Merkel, Bolognesi et ...anti-viral ...
9
Cost effectiveness of Interferon free therapy for Hepatitis C in Germany an application of the efficiency frontier approach
... Our analysis has shown that IQWIG's efficiency frontier approach is a suitable method to evaluate recent DAA approvals SOF and SMV for IFN-free therapy. In addition to higher sustained virologic response rates, ...
9
Incidence rates of tuberculosis in chronic hepatitis C infected patients with or without interferon based therapy: a population based cohort study in Taiwan
... underestimate the total number of MTB infected pa- tients. Third, some patients were treated with corticoste- roids, which are known to increase the risk of TB [38]. Although we adjusted for patients with connective ...
8
Drug Addiction and Hepatitis B&C in Pakistan
... chronic hepatitis and deaths due to liver failure and hepatocellular ...for hepatitis B and hepatitis C are not available at ...of hepatitis B and hepatitis C in Paki- ...
5
Therapeutic challenges in hepatitis C-infected injection drug using patients
... Other obstacles to treatment are less tangible. Mistrust of the medical community may influence patient willingness to be assessed and initiation of HCV antiviral therapy. This is, in part, fostered by multiple ...
6
Thrombotic thrombocytopenic purpura (TTP) associated with interferon therapy of hepatitis C
... interferon therapy, especially in patients with a history of TTP in the ...exchange therapy, every effort should be made to retrieve a pre-treatment blood sample on which to assay for ...
7
ANALYSIS OF PRESCRIPTION TREND IN THE TREATMENT OF HEPATITIS C AND THE STUDY OF ASSOCIATION OF THIS THERAPY PLAN WITH THE AGE OF THE PATIENT
... the drug(s) prescribed), here in this research, were studied simultaneously to check out the dependence of therapy plan on the age, results are shown in the table ...H1:The therapy plan for the ...
5
Pharmacogenomics of hepatitis C infections: personalizing therapy
... and Drug Administration (FDA) approval are the NS3 protease inhibitors boceprevir and ...dual therapy with PegIFN/R (<50%), and may allow reduction in treatment duration [49,50] (Table ...triple ...
10
Influence of Hepatitis B and Hepatitis C Virus Infections and Human Immunodeficiency Virus Therapy on Liver Status of Patients with Human Immunodeficiency Virus
... intravenous drug abusers, haemophiliacs and recipients of blood transfusions or vertical transmission (mother-to-child) which can occur during the birth process or during breast ...anti-retroviral therapy ...
14
PSYCHIATRIC DISORDERS INDUCED BY INTERFERON THERAPY OF CHRONIC HEPATITIS C PATIENTS: LONGITUDINAL STUDY
... Demographics. The patient’s age ranged from 42 to 70 years old, with an average age of 57.03 years old (SD = 11, 3). A total of 14 males and 16 females participated in the study. Pre-treatment psychiatric history was ...
8
Hepatitis C virus infection in Irish drug users and prisoners – a scoping review
... active drug use was identified as having a negative impact on treatment ...other drug use, concerns regarding relapse or mental health issues [91, ...
27
Hepatitis C and not Hepatitis B virus is a risk factor for anti tuberculosis drug induced liver injury
... of hepatitis including anorexia, nausea, vomiting, general- ized weakness, abdominal discomfort, and jaundice, and comorbidities including liver cirrhosis, chronic kidney disease, diabetes mellitus, hepatocecullar ...
7
Inter Individual Differences in Response to Cardiovascular Drug Therapy
... Inter Individual Differences in Response to Cardiovascular Drug Therapy Med J Malaysia Vol 43 No 1 March 1988 Inter Individual Differences in Response to Cardiovascular Drug Therapy C F GEORGE BSc, MD[.] ...
7
Rising rates of injection drug use associated infective endocarditis in Virginia with missed opportunities for addiction treatment referral: a retrospective cohort study
... of drug overdose related deaths in the United States [3] and is home to eight of the projected top 5% most vulnerable counties across the United States for viral outbreaks re- lated to IDU ...fatal drug ...
9
Natural and virtually designed flavonoids:Potential anti HCV targets in silico approach
... Flavonoids show docking score greater than ribavirin. (Table1. Entry 2, 3, 16, 18, 19) Therefore this result (Table 1) reveals that, there are good binding interactions between flavonoids and anti HCV protein. Due to ...
6