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Hepatoma Cells

TPP-related mitochondrial targeting copper (II) complex induces p53-dependent apoptosis in hepatoma cells through ROS-mediated activation of Drp1

TPP-related mitochondrial targeting copper (II) complex induces p53-dependent apoptosis in hepatoma cells through ROS-mediated activation of Drp1

... tumor cells due to their nuclease activity and DNA cleavage activit ...cancer cells (HepG2, SMMC-7721, BEL-7402, Huh-7, Hep3B) and human hepatocytes (LO2) at 24 h was tested by MTT analysis, showing that ...

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Original Article Hypoxia-related miR-210-5p and miR-210-3p regulate hypoxia-induced migration and epithelial-mesenchymal transition in hepatoma cells

Original Article Hypoxia-related miR-210-5p and miR-210-3p regulate hypoxia-induced migration and epithelial-mesenchymal transition in hepatoma cells

... of hepatoma cells in vitro and expression of epithelial-mesenchymal transition (EMT)-related proteins, including N-cadherin, MMP2, Slug, and ...in hepatoma cells and upregulated under ...in ...

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Genetically engineered drug rhCNB induces apoptosis and cell cycle arrest in both gastric cancer cells and hepatoma cells

Genetically engineered drug rhCNB induces apoptosis and cell cycle arrest in both gastric cancer cells and hepatoma cells

... human hepatoma cell lines Bel-7402 and HepG2 to different concentrations of rhCNB treatment for 24 ...of hepatoma cells in vitro. Bel-7402 cells were also implanted subcutaneously in BALB/c ...

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Aptamer Combined with Fluorescent Silica Nanoparticles for Detection of Hepatoma Cells

Aptamer Combined with Fluorescent Silica Nanoparticles for Detection of Hepatoma Cells

... detect hepatoma cells based on a biotin-labeled aptamer and streptavidin- modified ...tumor cells, coupled with the affinity and specificity of biotin for the streptavidin in SA-FSNPs, ensure highly ...

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Interferon alpha regulates MAPK and STAT1 pathways in human hepatoma cells

Interferon alpha regulates MAPK and STAT1 pathways in human hepatoma cells

... Hepatitis C virus (HCV) infection is the major cause of human liver diseases. IFN a is the current approved treatment for HCV infection [13]. We reported that the MAPK signaling pathways triggered by HCV envelope protein ...

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Mechanism of the Regulatory Effect of Overexpression of circMTO1 on Proliferation and Apoptosis of Hepatoma Cells via miR-9-5p/NOX4 Axis

<p>Mechanism of the Regulatory Effect of Overexpression of circMTO1 on Proliferation and Apoptosis of Hepatoma Cells via miR-9-5p/NOX4 Axis</p>

... 3A). Cells co-trans- fected with luciferase reporter plasmid carrying circMTO1 3 ʹ UTR wt and the miR-9-5p mimic showed signi fi cantly reduced fl uorescein levels compared to the cells trans- fected with the ...

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Hepatitis B Virus Inhibits Apoptosis of Hepatoma Cells by Sponging the MicroRNA 15a/16 Cluster

Hepatitis B Virus Inhibits Apoptosis of Hepatoma Cells by Sponging the MicroRNA 15a/16 Cluster

... Hepatitis B virus (HBV) causes chronic hepatitis in hundreds of millions of people worldwide, which can eventually lead to hepa- tocellular carcinoma (HCC). The molecular mechanisms underlying HBV persistence are not ...

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Baculovirus Entry into Human Hepatoma Cells

Baculovirus Entry into Human Hepatoma Cells

... Autographa californica multiple nucleopolyhedrovirus (AcMNPV), a prototype member of the Baculoviridae family, has gained increasing interest as a potential vector candidate for mammalian gene delivery applica- tions. ...

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Gene silencing of heparanase results in suppression of invasion and migration of hepatoma cells

Gene silencing of heparanase results in suppression of invasion and migration of hepatoma cells

... SiRNA-transfected hepatoma SMCC-7721 cells were har- vested at 48 h, 72 h and 96 h ...vested cells were washed and lysed with lysis buffer ...

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Conditional Replication of Duck Hepatitis B Virus in Hepatoma Cells

Conditional Replication of Duck Hepatitis B Virus in Hepatoma Cells

... Although the general mechanism of replication has been investigated in great detail, major gaps still exist because cer- tain intermediates of the replication cycle are either short lived or difficult to isolate in pure ...

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Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells

Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells

... liver cells were co-incubated with 125 μM of linoleic acid and 250 μM palmitic acid; further increasing the linoleic acid concentration to 250 μM reversed the suppressive effects of 125 μM linoleic acid on mRNA ...

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Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells

Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells

... epithelial cells adopting a partially polarized morphology in monolayer cul- ...Huh-7 hepatoma and clonal derivatives such as ...Huh-7.5 cells, in contrast to an earlier report demonstrating that ...

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High Permissivity of Human HepG2 Hepatoma Cells for Influenza Viruses

High Permissivity of Human HepG2 Hepatoma Cells for Influenza Viruses

... MDCK cells for influenza viruses were compared during two periods, January to March 2001 and January to March 2002, in a total of 82 samples (52 pediatric patients and 30 adults) received in our department for ...

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Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells

Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells

... The Tg737 gene (GenBank: U203621) is an important tumor suppressor gene in HCC [6]. In a previous investiga- tion, we showed that loss of heterozygosity (LOH) of the Tg737 gene at markers SHGC-57879 and G64212 closely ...

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HORMONAL REGULATION OF MEMBRANE PHENOTYPE IN HEPATOMA CELLS *

HORMONAL REGULATION OF MEMBRANE PHENOTYPE IN HEPATOMA CELLS *

... Because these variant cell lines also retain wild-type induction of tyrosine aminotransferase as well as inhibition of amino acid transport and induction of adhesiveness, it appears the [r] ...

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Lipoprotein binding to cultured human hepatoma cells

Lipoprotein binding to cultured human hepatoma cells

... G2 cells in lipoprotein-containing medium resulted in complete suppression of LDL receptors but did not affect the remnant ...G2 cells seem to be a suitable model for the study of hepatic receptors for ...

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Original Article miR-143 down-regulates TLR2 expression in hepatoma cells and inhibits hepatoma cell proliferation and invasion

Original Article miR-143 down-regulates TLR2 expression in hepatoma cells and inhibits hepatoma cell proliferation and invasion

... from hepatoma tissue stored in a -80°C freezer according to TRIzol reagent instructions; total RNA concen- tration and A260/280 ratio were measured with Nanodrop-2000, RNA within a ratio range of ...in ...

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RETRACTED ARTICLE: Gene expression profiling analysis of hepatocellular carcinoma

RETRACTED ARTICLE: Gene expression profiling analysis of hepatocellular carcinoma

... of hepatoma cells and normal cells In order to explore the differentially expressed genes and possible pathogenesis mechanisms in hepatoma cells com- pared to normal cells, we ...

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Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells

Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells

... Curcuma aromatica Salisb. is a popular type of trad- itional Chinese medicine plant whose essential oils are widely used in cancer treatment in China [14]. β-elemene (1-methyl-1-vinyl-2,4-diisopropenyl-cyclohexane), a ...

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Synthesis of liver-targeting dual-ligand modified GCGA/5-FU nanoparticles and their characteristics in vitro and in vivo

Synthesis of liver-targeting dual-ligand modified GCGA/5-FU nanoparticles and their characteristics in vitro and in vivo

... ideal nanoparticle size should be larger than the largest pore size of normal liver cells and smaller than the smallest pore size of hepatoma cells. Thus, the nanoparticle size should be between 175 ...

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