Hereditary breast cancer
The Pathology of Hereditary Breast Cancer
... familial breast cancers associated with BRCA1 or BRCA2 germline mutations differ in their morphological and immunohistochemical ...patients. Breast carcinomas from BRCA2 mutation carriers tend to be of ...
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Hereditary breast cancer associated with Cowden syndrome-related PTEN mutation with Lhermitte-Duclos disease
... for breast, thyroid, and endometrial ...for hereditary breast cancer associated with BRCA1 mutation is mastectomy because it is a more aggressive cancer with a poor ...PTEN-related ...
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Preparing young people for future decision making about cancer risk in families affected or at risk from hereditary breast cancer: A qualitative interview study
... ROWLAND, Emma, PLUMRIDGE, Gill, CONSIDINE, Anne-Marie and METCALFE, Alison (2016). Preparing young people for future decision-making about cancer risk in families affected or at risk from hereditary ...
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FOXC1 identifies basal-like breast cancer in a hereditary breast cancer cohort
... the hereditary breast cancer genes BRCA1 and BRCA2 are most commonly classified as basal-like breast cancer (BLBC) or luminal breast cancer, ...of breast ...
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Tumour spectrum in non-BRCA hereditary breast cancer families in Sweden
... with hereditary breast cancer who were sub- jected to genetic screening of BRCA1 and BRCA2 from February 2000 to January 2012 in the county of Stockholm, Sweden, were eligible for the ...verified ...
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Clinical and genetic characterization of hereditary breast cancer in a Chinese population
... In accordance with the American College of Medical Genetics (ACMG) recommendations for the interpretation of sequence, variants were classified into pathogenic, likely pathogenic, variant of uncertain significance (VUS), ...
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Hereditary breast cancer: ever more pieces to the polygenic puzzle
... Hereditary breast cancer represents a challenge in terms of genetic counselling as well as preventive and thera- peutic ...with breast cancer makes it possible to predict the ...
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TP53 p.R337H prevalence in a series of Brazilian hereditary breast cancer families
... with breast cancer at age ...with breast cancer at ages 42 and 35, ...prostate cancer after he turned ...tient: breast cancer personal history before 45 years old and ...
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Thymidylate synthase gene (TYMS) polymorphisms in sporadic and hereditary breast cancer
... have breast cancer below 35 years old and bilaterality; (ii) or, familiar with breast and/or ovarian cancer, one of whom diagnosed at the age below of 60 years old, or bilateral breast ...
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CHEK2 contribution to hereditary breast cancer in non BRCAfamilies
... CHEK2-Breast Cancer Consortium: Low-penetrance susceptibility to breast cancer due to CHEK2 *1100delC in noncarriers of BRCA1 or BRCA2 ...
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Strong evidence that the common variant S384F in BRCA2has no pathogenic relevance in hereditary breast cancer
... by breast cancer carried the variant, one was lacking ...bi-lateral breast can- cer at 32 and 50 years of age so it is very unlikely that this patient suffered from sporadic breast ...
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Patients with pathogenic variants for breast cancer other than BRCA1 and BRCA2: qualitative interviews about health care experiences
... gesting hereditary cancer ...test, hereditary breast cancer panel, and hereditary breast and gynecologic cancer gene panel from January 2012 through May 2018; genes ...
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The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services
... on breast screening, hereditary breast cancer clinics and genetics services in the USA, Canada, Australia, New Zealand and the UK ...in breast cancer referrals for genetics, ...
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Population screening for hereditary and familial cancer syndromes in Valka district of Latvia
... of hereditary cancer burden by loca- tion in the same group was obtained by population ...of hereditary colorectal cancer corresponds to the wide published spectrum of 1 - 13% but is lower ...
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Medical Oncology Unit, National Cancer Research Centre, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.
... BReast Cancer (BRCA)1- and BRCA2-associated hereditary breast and ovarian cancer syndrome (HBOC) is characterized by an increased risk for female and male breast cancer, ...
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Hereditary breast and ovarian cancer
... Familial breast cancer was first recognized in the Roman medical literature of 100 AD ...of breast cancer in modern times was published by Broca, who reported 10 cases of breast ...
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“Philosophical Treatises on Life and Death”:Newspaper Coverage of a Controversial Brain Death Case
... of cancer telegenetics use in a geographically remote setting of Maine, it was found that this model may also help increase access to cancer genetic counseling services in underserved areas (McDonald ...
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DNA-testing for BRCA1/2 prior to genetic counselling in patients with breast cancer: design of an intervention study, DNA-direct
... with breast cancer at high risk of an underlying hereditary predisposition face a time-consuming diagnostic process of several months: it might be helpful to be able to cut down on this long period ...
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Do hereditary syndrome-related gynecologic cancers have any specific features?
... which hereditary breast- ovarian cancer and hereditary non-polyposis colon cancer syndromes, known as HBOC and Lynch syndromes re- spectively, present the highest relative ...
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Role of BRCAgene dysfunction in breast and ovarian cancer predisposition
... mutated cancer cell lines reveal abnormally delayed kinet- ics of double-strand break repair (DSBR) ...BRCA1-mutated breast cancer cell line ...
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