Hexokinase activity
Hemolytic anemia with impaired hexokinase activity
... decreased hexokinase activity underlies the hemolytic process in the two members with overt ...trait. Hexokinase activity was labile in distilled water hemolysates but was only slightly low ...
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Inorganic Polyphosphates Regulate Hexokinase Activity and Reactive Oxygen Species Generation in Mitochondria of Rhipicephalus (Boophilus) microplus Embryo
... The metabolism of free hexoses begins by phosphorylation in a reaction catalyzed by the hexo- kinase (ATP: hexose-6-phosphotransferase, E.C. 2.7.1.1; HK). This enzyme has been characterized in several organisms [19-24]. ...
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Indications for a central role of hexokinase activity in natural variation of heat acclimation in Arabidopsis thaliana
... Activity of sucrose phosphate synthase (SPS) was determined using the anthrone assay as described earlier [31]. Frozen leaf tissue was suspended in extraction buffer containing 50mM HEPES-KOH (pH 7.5), 10mM MgCl2, ...
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SALL4 promotes gastric cancer progression via hexokinase II mediated glycolysis
... dehydrogenase activity, ATP level, and hexokinase ...of hexokinase II (HK-2) by SALL4 was analyzed by luciferase reporter assay and chromatin immunoprecipitation ...
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Identification of functional metabolic biomarkers from lung cancer patient serum using PEP technology
... enzyme activity was monitored by the 340 nm absorbance from the reduction of NADP to ...endogenous Hexokinase activity present in the beef liver extract, and any exogenous activity from the ...
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Activity of a Second Trypanosoma brucei Hexokinase Is Controlled by an 18-Amino-Acid C-Terminal Tail
... Recombinant TbHK1 has hexokinase activity in vitro. Why does T. brucei harbor two nearly identical HK genes? We initially considered three possible explanations. First, the two proteins could be expressed ...
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Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function
... Fig.·1, hexokinase serves as the gateway through which Glc enters alternative metabolic ...that hexokinase is most commonly thought of as a glycolytic enzyme, and glycolytic metabolism is generally ...
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Activity of Hexokinase Is Increased by Its Interaction with Hepatitis C Virus Protein NS5A
... HK activity, the first rate-limiting enzyme of glycolysis, will pro- mote the increase of glucose flux due to the upregulation of down- stream glycolytic ...HK activity may be an effi- cient strategy for ...
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Inhibition of oxidative phosphorylation suppresses the development of osimertinib resistance in a preclinical model of EGFR-driven lung adenocarcinoma
... measuring hexokinase activity – the first enzymatic step in glycolysis - on similarly treated ...reduced hexokinase activity after drug treatment, whereas NCI-H1975 cells with acquired ...
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AMELIORATIVE EFFECT OF Coccinia grandis LEAF EXTRACT ON NEUROCHEMICAL ALTERATIONS OF SCIATIC NERVE IN STZ INDUCED DIABETIC RATS
... as hexokinase, aldose reductase, sorbitol dehydrogenase and glucose-6-phosphate dehydrogenase were also determined after 3 ...reduced hexokinase activity in STZ induced diabetic rats indicated a ...
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Effects of Potentilla Fulgens Linn. on Carbohydrate and Lipid Profiles in Diabetic Mice
... The effects on carbohydrate and lipid profiles of the anti-diabetic plant, Potentilla fulgens Linn. (Rosaceae), were evaluated in alloxan-induced diabetic mice. The methanol extract of P. fulgens at the optimized dose of ...
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Purification and properties of human hexokinase.
... low hexokinase activity, a single band stained for hexo- kinase activity was observed corresponding to the single. band stained for protein[r] ...
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Antihyperglycemic and Antihyperlipemic Effects of Mangifera Indica L. in Fluoride Induced Toxicity
... A chronic intake of fluoride through food and drinking water is also known to cause hyperglycemia and dyslipidemia besides fluorosis. The present study deals with the effects of fluoride (100 ppm) induced hyperglycemia ...
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Investigations on malic acid utilisation in Schizosaccharomyces species : a thesis presented in partial fulfilment of the requirements for the degree in Doctor of Philosophy in Genetics at Massey University
... gluc ose transport Km 2 mM, that is induced at low concentrations of glucose and a low affinity tran sport Km 20 mM Does and Bis son 1 9 89.. IS dependent on hexokinase activity Lang and[r] ...
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OXYGEN CONSUMPTION, CARBON DIOXIDE PRODUCTION AND ENZYME ACTIVITIES OF ISOLATED WORKING OCTOPUS HEART
... Power output, oxygen consumption, carbon dioxide production and enzyme activity levels in Octopus vulgaris systemic heart Power output mWg"1 --'mirr 1 /Wco, G"mol g min Hexokinase ^mol[r] ...
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Hexokinase 2 is dispensable for T cell-dependent immunity
... Cancer cells highly upregulate HK2 compared to their normal tissue of origin and it is required for tumorigenesis in a variety of mouse cancer models, including breast and lung cancer an[r] ...
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THE GENETICS OF HEXOKINASE IN A MOSQUITO, CULEX PIPIENS
... Re-electrophoresis: The zymogram (Figure 3) shows that each of the three isozymes migrated to its relative original position and remained as single bands after re-electrophoresis.[r] ...
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IN-SILICO STRUCTURE-ACTIVITY RELATIONSHIP AND MOLECULAR DOCKING STUDY OF NEROLIDOL AND ITS MODIFIED ANALOGUE AGAINST THE TRYPANOSOMA BRUCEI HEXOKINASE
... brucei hexokinase amino acid sequence was retrieved from the National Center for Biotechnology Information (NCBI) ...brucei hexokinase was assigned the accession number of ...
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Impaired activity and gene expression of hexokinase II in muscle from non insulin dependent diabetes mellitus patients
... HKII activity and gene expression are impaired in vastus lateralis muscle of NIDDM patients when examined in the fasting ...HKII activity in a supernatant of muscle extract accounted for 28 +/- 5% in NIDDM ...
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Isolation, Identification and Growth Optimisation of Freshwater Microalgae
... Temperature and light are important factors affecting the growth of microalgae. The temperature can change the photosynthetic and respiration intensity of microalgae by affecting the activity of the related ...
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