high dose cytarabine
Clinical significance of high-dose cytarabine added to cyclophosphamide/total-body irradiation in bone marrow or peripheral blood stem cell transplantation for myeloid malignancy
... HDCA high-dose cytarabine, PS performance status, HCT-CI hematopoietic cell transplant co-morbidity index, CMV cytomegalovirus, AML acute myelogenous leukemia, MDS myelodysplastic syndrome, Rel ...
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Rituximab, etoposide, methylprednisolone, high dose cytarabine, and cisplatin in the treatment of secondary hemophagocytic lymphohistiocytosis with classical Hodgkin lymphoma: a case report and review of the literature
... Case presentation: A 66-year-old Hispanic man previously in good health presented with a 1-month history of recurrent fevers, chills, and night sweats and a 3-week history of new onset jaundice. A bone marrow biopsy ...
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Reinduction Chemotherapy with Gemtuzumab Ozogamicin and Intermediate/High Dose Cytarabine: A Single Center Experience
... We performed a retrospective analysis of adult patients who were treated with GO as salvage induction chemo- therapy from March 2009 to August 2011 at Ibaraki Prefectural Central Hospital, Ibaraki, Japan. AML was di- ...
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The prognostic impact of K-RAS mutations in adult acute myeloid leukemia patients treated with high-dose cytarabine
... ara-C dose used in consolidation treatment, the high the dose ara-C (HDAC) group receiving 400 mg ara-C and-low-dose ara-C (LDAC) group receiving 100 mg ara-C; they were followed over a period ...
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A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia
... 70% and a low induction death rate of 5%. This phase I study demonstrates that this first-in-class SINE com- pound has an acceptable toxicity profile at the tested doses of 60 and 80 mg. The MTD was not determined, and ...
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Advances in the drug therapies of acute myeloid leukemia (except acute promyelocytic leukemia)
... higher received midostaurin combination with bortezomib following chemotherapy with mitoxantrone, etoposide, and cytarabine. The results indicated that none of patients on DL1 and DL2 achieved dose-limiting ...
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Abstract: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by
... this dose schedule for adults <60 year old and showed that higher dose (3 g/m 2 ) as compared to lower dose ...) cytarabine for three courses led to identical outcomes ...low dose ...
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Optimization of cytarabine (ARA-C) therapy for acute myeloid leukemia
... intermediate dose (ID) of ARA-C in the range of 1,000 to 2,000 mg per square meter ...of high-dose cytarabine for acute myeloid leukemia,” he states that the data from sev- eral clinical ...
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HDMTX-based induction therapy followed by consolidation with conventional systemic chemotherapy and intraventricular therapy (modified Bonn protocol) in primary CNS lymphoma: a monocentric retrospective analysis
... [3]. High-dose methotrexate (HDMTX) is the most active drug in ...a high rate of delayed neurotoxicity, particularly in the elderly ...and High-dose cytarabine (HDAraC)- based ...
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Case Report Safe and effective induction therapy with CHASER for primary testicular lymphoma with central nervous system involvement
... Abstract: Primary testicular lymphoma (PTL) is a rare, aggressive form of non-Hodgkin’s lymphoma (NHL) with a poor prognosis. The standard treatment strategy for cases of PTL with advanced stage at diagnosis, especially ...
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FLT3-ITD Negative Refractory/Relapsed or Geratic AML Patients Responded Well to Salvage Treatment with Low Dose Cytarabine and Sorafenib
... fludarabine, high-dose cytarabine, and granulocyte clony-stimulation factor (FLAG) plus idarubine and gemtuzumab-ozogamicin induced CR/CRi of 51% with 9% induction death in salvage of R/R AML ...
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<p>Organ accumulation and carcinogenicity of highly dispersed multi-walled carbon nanotubes administered intravenously in transgenic rasH2 mice</p>
... developed mesothelioma that was thought to originate from the pleura (Figure 3A and B), but all other cases were adenomas (Figure 3C and D). Although we checked for the presence of thin- and thick-MWCNTs in cases with ...
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Nutraceutical with Anti Inflammatory Activity for the Management of Airway Remodeling in Bronchial Asthma: Kalanchoe integra Var Crenata (Andr ) Cuf Leaf Extract
... Apart from the fact that phagocytes are among the many inflammatory cells and mediators released during severe infections or antigenic exposure in the lungs, neutrophils are also implicated in exacerbations of acute ...
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The combination of valproic acid, all-trans retinoic acid and low-dose cytarabine as disease-stabilizing treatment in acute myeloid leukemia
... low-dose cytarabine is effective and feasible, but in our opinion it is difficult to judge whether it is superior to hydroxyurea or ...low-dose cytarabine has been documented in sev- eral ...
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An Investigation into the Role of Insulin in Pain Threshold.
... in high concentrations increases the circulating levels of insulin without change in ...insulin dose dependently lower the second phase of formalin induced pain but it does not significantly lower the blood ...
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Homoharringtonine and omacetaxine for myeloid hematological malignancies
... Leukemia initiating cells (LICs) are a population of stem cells that are capable of tumor initiation and maintenance of the disease. LICs in CML are thought to reside in a population of Bcr-Abl positive cells with ...
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High-energy, high-dose O implantation in Si
... Various parameters deduced from modeling of the samples in Fig. 3.8(b) are listed in Table III. (The VEP spectra for samples 4 and 5 are not shown.) It should be noted that the layer 1 and 2 thicknesses of the buried ...
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Efficacy and safety of decitabine in combination with G-CSF, low-dose cytarabine and aclarubicin in newly diagnosed elderly patients with acute myeloid leukemia
... and cytarabine showed an additive or synergistic effect on cell death in human leukemia cell lines in ...to cytarabine-based intensive chemotherapy, our D-CAG-based intensive chemotherapy also showed a ...
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Dissolution characteristics of anti cancer drug Cytarabine
... the cytarabine quality increases, but the molar enthalpy remains constant, therefore the average of molar enthalpy calculated under different mass can be used as the infinite dilution molar enthalpy of ...
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Trends in high-dose opioid prescribing in Canada
... of high-dose hydromorphone dispensing in ...of high-dose oxy- codone dispensing, while Prince Edward Island, British Columbia, and Nova Scotia restrict reimbursement for this formulation to ...
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