High grade serous
Nadir CA-125 level as prognosis indicator of high-grade serous ovarian cancer
... the serous, endometrioid, mu- cinous, clear-cell, and undifferentiated carcinomas, as well as in malignant Brenner and mixed mesodermal tumors ...of high-grade serous ovarian carcinoma ...
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<p><em>Chlamydia trachomatis</em> infection in primary fallopian tube and high-grade serous ovarian cancers: a pilot study</p>
... primary serous tubal and high-grade serous ovarian cancers in comparison to fallopian tubes retrieved from patients who underwent hys- terectomy with bilateral salpingo-oophorectomy for benign ...
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Ovarian low and high grade serous carcinomas: hidden divergent features in the tumor microenvironment
... low-grade serous carcinoma (LGSOC) of the ovary has been recognized as a disease entity distinct from the more common high-grade serous carcinoma (HGSOC), with significant differences ...
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Role of the immune system in the peritoneal tumor spread of high grade serous ovarian cancer
... The immune system plays a critical role in cancer progression and overall survival. Still, it is unclear if differences in the immune response are associated with different patterns of tumor spread apparent in ...
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Original Article Characterization of desmoglein 2 expression in ovarian serous tumors and its prognostic significance in high-grade serous carcinoma
... subtypes: serous, endometrioid, mucinous, clear cell, and undif- ferentiated carcinoma [21, ...Because serous carcinoma usually represents the arche- typical EOC and is responsible for the highest fatality ...
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Original Article High-grade serous ovarian and fallopian tube carcinomas with similar clinicopathological characteristics might originate from serous tubal intraepithelial carcinoma in Chinese women
... of high-grade serous carcinoma ...survival. Serous tubal intraepithelial carcinoma (STIC) were found in ...ovarian high-grade serous carcinoma (HGSC) and ...
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Advances in Tumor Screening, Imaging, and Avatar Technologies for High-Grade Serous Ovarian Cancer
... in high-risk women and BRCA mutation carri- ...of high-grade serous tumors being detected using this method when compared to other ovarian cancer subtypes ...
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MRI for differentiating ovarian endometrioid adenocarcinoma from high-grade serous adenocarcinoma
... (high-grade serous adenocarcinoma, endometrioid carcinoma, clear cell carcinoma, mucinous carcinoma, low-grade serous adenocarcinoma) ...histologic grade, respond well to ...
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The role of KIF14 in patient-derived primary cultures of high-grade serous ovarian cancer cells
... Out of the 29 high-grade serous primary samples re- ceived, only 11 samples were developed into short-term cultures. The remaining 18 samples were processed, but no cells were outgrown/retrieved ...
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High levels of pretreatment CA125 are associated to improved survival in high grade serous ovarian carcinoma
... with high grade serous carcinoma (HGSC), FIGO stage III and pretreatment serum CA125 level higher than 500 ...differentiation grade on CA125 levels; this influence was corroborated in the ...
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Review Article Advances in serous tubal intraepithelial carcinoma: correlation with high grade serous carcinoma and ovarian carcinogenesis
... Early serous carcinoma in fallopian tube or serous tubal intraepithelial carcinoma (STIC), an early lesion limited to the epithelium of the fallopian tube and firstly identified from specimen obtained by ...
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High-grade serous ovarian carcinoma with mucinous differentiation: report of a rare and unique case suggesting transition from the “SET” feature of high-grade serous carcinoma to the “STEM” feature
... entiation, high-grade serous carcinoma (HGSC) quite differs from low-grade serous carcinoma (LGSC) in re- gard to clinicopathological features [6, ...two serous carcinomas, p53 ...
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High-grade serous carcinoma with discordant p53 signature: report of a case with new insight regarding high-grade serous carcinogenesis
... in high-grade serous carcinogenesis, identification of the null- and/or cyto- plasmic staining-type TP53-mutated normally-appearing cells is required in the ...
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Original Article An orthotopic model of platinum-sensitive high grade serous fallopian tube carcinoma
... of serous ovarian tumor carcinogenesis, high grade se- rous tumors originate as serous tubal intraepi- thelial carcinoma (STIC) precursor lesions in the fallopian tube, prior to spreading to ...
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Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma
... that high-grade serous carcinoma (HGSC) arises from the ovarian surface epithelium (OSE), recent studies suggest that additional sites of origin exist and a substantial proportion of cases may arise ...
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Kallistatin inhibits tumour progression and platinum resistance in high-grade serous ovarian cancer
... Sections of 4 μm were cut from each TMA receiver block, made by our laboratory. After deparaffinization in xylene and rehydration in a decreasing series of ethanol, slides were immersed in boiled 10 mmol/L EDTA buffer ...
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Prognostically relevant gene signatures of high grade serous ovarian carcinoma
... with high expression of Mesenchymal signatures are specifically sensitive to angiogenesis ...in serous ovarian cancer, in which a subset of samples shows a mesenchymal ...
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Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma
... nuclear grade, nuclear cytoplasmic ratio (N/C ratio), tumor stroma, mitotic index, and tumor necrosis were analyzed for the eight cases that were successfully engrafted at all passages ...and grade in P2 ...
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Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma
... Validation of a highly sensitive and specific ADRM1 Chromogenic In Situ Hybridization (CISH) assay. A) ADRM1 mRNA levels in samples from 4 HGSC patients with matched FFPE blocks and froz[r] ...
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DEF6 expression in ovarian carcinoma correlates with poor patient survival
... of serous tubal intraepithelial carcinomas ...ovarian/tubal high grade serous carcinomas revealed three distinct subgroups according to p16 ex- pression and RB1 status ...
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