high grade serous carcinoma
Magnetic resonance imaging for distinguishing ovarian clear cell carcinoma from high-grade serous carcinoma
... cell carcinoma (CCC) has recently emerged as the second most common type of epithelial ovarian cancers (EOCs), representing 5 – 25 % of ovarian ...ovarian high-grade serous carcinoma ...
8
Original Article Characterization of desmoglein 2 expression in ovarian serous tumors and its prognostic significance in high-grade serous carcinoma
... ovarian serous tumor (OST) and its associations with survival and clinicopathologic ...and high-grade) by using qRT-PCR and immunohistochemistry, ...of high-grade serous ...
11
Review Article Advances in serous tubal intraepithelial carcinoma: correlation with high grade serous carcinoma and ovarian carcinogenesis
... Early serous carcinoma in fallopian tube or serous tubal intraepithelial carcinoma (STIC), an early lesion limited to the epithelium of the fallopian tube and firstly identified from specimen ...
10
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma
... that high-grade serous carcinoma (HGSC) arises from the ovarian surface epithelium (OSE), recent studies suggest that additional sites of origin exist and a substantial proportion of cases may ...
19
High-grade serous ovarian carcinoma with mucinous differentiation: report of a rare and unique case suggesting transition from the “SET” feature of high-grade serous carcinoma to the “STEM” feature
... entiation, high-grade serous carcinoma (HGSC) quite differs from low-grade serous carcinoma (LGSC) in re- gard to clinicopathological features [6, ...ovarian ...
6
High-grade serous carcinoma with discordant p53 signature: report of a case with new insight regarding high-grade serous carcinogenesis
... Case presentation: A 56-year-old woman was referred to the gynecologist on account of abdominal distention. Since radiological and serological workup suggested that her illness was due to advanced ovarian cancer (FIGO ...
6
Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma
... The presence of detectable RNA in the tissue samples was verified by using positive control peptidyl prolyl isomerase B (PPIB) probe (Additional file 2: Figure S2). Next, we utilized the ADRM1 mRNA CISH assay to probe ...
12
High levels of pretreatment CA125 are associated to improved survival in high grade serous ovarian carcinoma
... with high grade serous carcinoma (HGSC), FIGO stage III and pretreatment serum CA125 level higher than 500 ...differentiation grade on CA125 levels; this influence was corroborated in ...
6
A survival analysis comparing women with ovarian low-grade serous carcinoma to those with high-grade histology
... and high-grade serous carcinomas. Low-grade serous carcinoma (LGSC) represents less than 10% of all cases of serous ovarian ...genes. High-grade ...
9
The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma
... IL-8 mediates its biological effects via the two receptors, IL-8RA and IL-8RB. IL-8RA binds to granulocyte chemotactic protein-2 and IL-8 only. In contrast IL-8RB is more promiscuous and in addition to IL-8 is activated ...
11
Click here to download PDF version of the article !
... at high risk for serous ovarian ...with high grade serous cancers ranged from 11% to 61% (mean: 31%, 95% CI: 17-46%) ...of serous tubal intraepithelial carcinoma in women ...
5
Original Article Diagnostic value of dual detection of hepatocyte nuclear factor 1 beta (HNF-1β) and napsin A for diagnosing ovarian clear cell carcinoma
... cell carcinoma, 30 cases of high- grade serous carcinoma, 22 cases of endome- trioid adenocarcinoma, and 16 cases of meta- static Krukenberg ...
6
The role of histone lysine methyltransferase NSD3 in cancer
... Abbreviations: AML, acute myeloid leukemia; BRD4, bromodomain-containing protein 4; CHD8, chromodomain-helicase-DNA-binding protein 8; HGSC, high-grade serous carcinoma; [r] ...
6
DEF6 expression in ovarian carcinoma correlates with poor patient survival
... or high-grade serous carcinoma, mucinous carcin- oma, endometrioid carcinoma and clear cell carcinoma), stage, therapy, recurrence free interval (if applicable), and site of ...
10
Development of Peritoneal Carcinoma in women diagnosed with Serous Tubal Intraepithelial Carcinoma (STIC) following Risk-Reducing Salpingo-Oophorectomy (RRSO)
... ovarian carcinoma at the time of ...had high grade serous peritoneal carcinoma diagnosed at 53 and 75 ...developed high grade serous carcinoma of peritoneal ...
6
Comparative analysis of Rb1, P16 and ER as diagnostic, prognostic and potential targets for therapeutic agents in ovarian epithelial tumors: an immunohistochemical study of 130 ovarian carcinomas
... tumor grade in representative cases of ovarian serous ...Notice high nuclear expression of Rb1 in low grade serous carcinoma (LGSC) compared to weak positive staining in ...
6
Original Article An orthotopic model of platinum-sensitive high grade serous fallopian tube carcinoma
... a high grade serous carcinoma arising from the left FT, with an associated STIC lesion and “p53 signature” of normal appearing fallopian ...The carcinoma displayed classic morphologic ...
9
Low-grade serous carcinoma of the ovary: A case series and literature review
... low-grade serous carcinoma, the standard is maximum cytoreductive surgery, with the goal of achieving minimal residual ...with grade 1 (low-grade) serous carcinoma were ...
7
Original Article High-grade serous ovarian and fallopian tube carcinomas with similar clinicopathological characteristics might originate from serous tubal intraepithelial carcinoma in Chinese women
... ovarian carcinoma (OC) and fallopian tube carcinoma (FTC) in Chinese women and to analyze the origin of high-grade serous carcinoma ...survival. Serous tubal ...
11
Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma
... The genomic DNA of nine primary cases was extracted and purified using the QIAamp DNA FFPE Tissue Kit (QIAGEN) according to the manual. P53 exon4-9 muta- tion analysis was conducted as previously described [10]. In ...
11