High –grade squamous intraepithelial lesion:
High-grade squamous intraepithelial lesion arising adjacent to vulvar lymphangioma circumscriptum: a tertiary institutional experience
... system, it is a very rare condition. Vulvar LC can also be acquired by uterine cancer patients who have undergone radical hysterectomy, pelvic lymph node dissection, and/ or pelvic radiation therapy that damages the ...
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Type-specific high-risk human papillomavirus viral load as a viable triage indicator for high-grade squamous intraepithelial lesion: a nested case–control study
... other high-risk types (yes or ...HR-HPV, high-risk human papillomavirus; ≥HSIL, high-grade squamous intraepithelial lesion or worse; NILM/LSIL, negative for ...
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Original Article Feasibility and efficacy of vaginectomy for patients with vaginal vault high-grade squamous intraepithelial lesion after hysterectomy: a retrospective analysis of 52 cases
... Mingzhi Zhao, Jianfeng Zhang, Guoqian Wei, Changdong Hu, Zhiling Zhu Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China Received June 8, 2017; Accepted June 30, 2017; Epub ...
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Rare subtype(s) and frequency of multi-viral subtype high-risk human papilloma virus infection in high-grade squamous intraepithelial lesion and squamous cell carcinoma in a cervical carcinoma prevalent developing country: a multiplex real-time polymerase chain reaction-based pilot study
... Methods: Forty cases of cervical High-Grade squamous intraepithelial lesion (HSIL) and Squamous cell carcinoma (SqCa) were collected. DNA was extracted from tissue representing ...
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High Risk HPV E6/E7 Oncoprotein Expression in Women with High Grade Squamous Intraepithelial Lesion
... the lesion. 8,9 Thus, E6/E7 mRNA detection can have a high prognostic value and can improve the speci ficity and positive predictive value when compared with the HPV- DNA ...cervical intraepithelial ...
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Original Article Morphoproteomic Evidence of Constitutively Activated and Overexpressed mTOR Pathway in Cervical Squamous Carcinoma and High Grade Squamous Intraepithelial Lesions
... in Squamous Cervical Neoplasm Figure 5 A schematic composite of the complex protein circuitries identified by the authors and others utilizing immunohistochemistry in cases of HSIL and/or invasive squamous ...
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Detection of HPV RNA molecules in stratified mucin producing intraepithelial lesion (SMILE) with concurrent cervical intraepithelial lesion: a case report
... and high-grade squamous intraepithelial lesion (HSIL) on her ...The lesion was found to be positive for HPV genotypes 52 and 68 by multiplex ...
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Sensitivity and specificity of HR HPV E6/E7 mRNA test in detecting cervical squamous intraepithelial lesion and cervical cancer
... Yao Yl et al. in 2017 confirmed the relevance of HR HPV E6/E7 mRNA test in monitoring HR HPV positive patients. In the abovementioned paper no statistically relevant differ- ence was shown between the sensitivity and ...
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A low-cost HPV immunochromatographic assay to detect high-grade cervical intraepithelial neoplasia
... Only a cohort study could answer this issue. However, one question remains: would it be ethi- cally acceptable not to offer any treatment to women with a confirmed diagnoses of CIN3 and HPV16/18 infection? Table 6. ...
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Biomarkers Expression in Cervical Cancer and High Grade Squamous Intraepithelial Lesions
... HIF-1α, VEGF and EpoR expression were analyzed in tissue samples by immunohistochemistry using commercial antibodies. Expression and overexpression of the tumor markers were quantified according to German Immunoreactive ...
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Original Article p16INK4a and Ki-67 measurement predict progression of cervical low-grade squamous intraepithelial lesion
... Large sample sizes are needed to further vali- date these findings. This study has some limitations. First, prior to the first biopsy, the number of HPV-positive patients was not counted. HC2 was used only in the ...
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Colposcopic characteristics and Lugol׳s staining differentiate anal high-grade and low-grade squamous intraepithelial lesions during high resolution anoscopy
... Each lesion was evaluated and coded for the presence or absence of speci fic lesion characteristics using colposcopic criteria commonly used in gyne- cology and previously validated for anal lesions ...AWE ...
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Cytologic surveillance versus immediate colposcopy for women with a cervical smear diagnosis of low-grade squamous intraepithelial lesion in a poor setting in Nigeria
... a high persistence rate of LSIL and a high default rate from cytologic surveillance at 6 months’ follow-up highlight the need to consider immediate referral to colposcopy, where available, for all women ...
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Preinvasive and invasive disease in women with cytological diagnosis of high-grade lesion and high-grade lesion cannot exclude microinvasion
... SITEC: Seção Integrada de Tecnologia em Citopatologia of Instituto Nacional de Câncer; IFF/Fiocruz: Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira of Fundação Oswaldo Cruz; Inca: ...
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Cytokeratin7 and cytokeratin19 expression in high grade cervical intraepithelial neoplasm and squamous cell carcinoma and their possible association in cervical carcinogenesis
... There are still questions left unresolved in this study. The first is how the cells with stem cell character were simultaneously present in the upper layer and the lower layer of CIN3 showing CK7 and CK19 positivity, ...
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Analysis of promoter methylation of four cancer-related genes in samples of cervical tissue with high-grade squamous intraepithelial lesions, squamous cell carcinoma in situ, and early squamous cell carcinoma
... targeted lesion, including 11 samples with HSIL, 20 with squamous cell carcinoma (SCC) in situ (SCIS), and 16 with invasive SCC at an early stage (pT1a2 or ...
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Comparison of Linear Array and Line Blot Assay for Detection of Human Papillomavirus and Diagnosis of Cervical Precancer and Cancer in the Atypical Squamous Cell of Undetermined Significance and Low Grade Squamous Intraepithelial Lesion Triage Study
... in a population of women referred to ALTS because of an ASCUS Pap test and therefore potentially useful as a triage test to determine who is referred to colposcopy. There was a notable increase in analytic sensitivity ...
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γH2Ax Expression as a Potential Biomarker Differentiating between Low and High Grade Cervical Squamous Intraepithelial Lesions (SIL) and High Risk HPV Related SIL.
... with high-risk oncogenic ...a high risk HPV type (LGSIL-HR) at an activated ...the lesion (most biopsies harboring limited areas of HGSIL) as well as to other factors promoting H2AX phosphorylation ...
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Comparison of the diagnostic value of cervical cytology and HPV HR DNA testing for the diagnosis of low-grade and high-grade squamous intraepithelial lesions across different age groups
... MATERIAL AND METHODS Between 2011 and 2014, 1103 patients aged 25 and older underwent in-depth diagnostics at the Laboratory of Cervical Pathophysiology, Gynecology and Obstetrics Clinical Hospital, Karol Marcinkowski ...
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Use of colposcopy for detection of squamous intraepithelial lesions
... as squamous metaplasia, which includes proliferation of undifferentiated reserve cells, columnar cells and their transformation into the squamous ...low grade level (LGSIL) and during the time could ...
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