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hippocampal neurons

Erythropoietin affects GABAergic transmission in hippocampal neurons in vitro

Erythropoietin affects GABAergic transmission in hippocampal neurons in vitro

... Abstract: Erythropoietin is a potent regulator of erythropoiesis. It acts via the specific membrane receptor (EpoR). Erythropoietin is also known to be present in the central nervous system, and its concentration and the ...

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The planar cell polarity protein Vangl2 bidirectionally regulates dendritic branching in cultured hippocampal neurons

The planar cell polarity protein Vangl2 bidirectionally regulates dendritic branching in cultured hippocampal neurons

... of hippocampal neurons were prepared from eighteen day old pregnant Wistar rats as de- scribed previously ...[17,18]. Neurons were transfected with shRNA constructs or various mutants of HA-Vangl2 ...

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Proteoglycans involved in bidirectional communication between mast cells and hippocampal neurons

Proteoglycans involved in bidirectional communication between mast cells and hippocampal neurons

... However, it was reported that histamine potentiates NMDA-mediated synaptic transmission and excitotoxi- city in hippocampal neurons [58, 59]. When histamine is co-released simultaneously with CS, as it ...

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Effects of dalteparin on structure of hippocampal neurons of rats in chronic stress

Effects of dalteparin on structure of hippocampal neurons of rats in chronic stress

... of neurons to inflammation depends on both the duration and region ...of neurons in ...hippocampal neurons. It indicates that dalteparin could protect hippocampal neurons from ...

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Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase

Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase

... In this study, we generated transgenic mice expressing BACE1-YFP, and for the first time, visualized BACE1 dy- namic axonal transport in situ within the mossy fibers of the hippocampus by multiphoton microscopy. ...

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Semaphorin 5B mediates synapse elimination in hippocampal neurons

Semaphorin 5B mediates synapse elimination in hippocampal neurons

... Sema5B, neurons were cocultured with HEK293 cells transiently transfected with HA-Sema5B or a variety of truncated/deletion ...culture hippocampal neurites were observed to avoid con- tact with HEK293 cells ...

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Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons

Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons

... in hippocampal neurons [25], sensory neurons [26], and neural stem cells ...that neurons can synthesize chemokines, as well as the cyto- kines tumor necrosis factor alpha and IL-6 in response ...

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Original Article Tanshinone IIA pretreatment attenuates oxygen-glucose deprivation induced hippocampal neurons damage

Original Article Tanshinone IIA pretreatment attenuates oxygen-glucose deprivation induced hippocampal neurons damage

... the hippocampal neurons were increased, ATP level decreased, and intra- cellular caspase 3 activated in this ...the neurons were attenuated by Tan IIA pretreatment in a concen- tration-dependent ...

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Dynamic transport and localization of alpha-synuclein in primary hippocampal neurons

Dynamic transport and localization of alpha-synuclein in primary hippocampal neurons

... Results: To investigate the role of the helical domain in transport and localization of a -synuclein, eGFP-tagged constructs were transfected into rat primary hippocampal neurons at 7 DIV. A series of ...

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Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits

Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits

... for hippocampal newborn DGCs in the formation of proepi- leptic neural circuits and the expression of seizures during ...projection neurons that relay the information mainly originating in the EC to CA3, ...

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Bwlding the Molecular Machinery of Memory: Local Protein Synthesis in Hippocampal Neurons

Bwlding the Molecular Machinery of Memory: Local Protein Synthesis in Hippocampal Neurons

... Using radiolabeling, Feig and Lipton 1993 showed that newly synthesized proteins could be detected in dendrites of hippocampal slices-the timing was such that the cell body was unlikely [r] ...

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The Effect of Scopolamine on Avoidance Memory and Hippocampal Neurons in Male Wistar Rats

The Effect of Scopolamine on Avoidance Memory and Hippocampal Neurons in Male Wistar Rats

... cholinergic neurons in the amygdala on learning and memory, topical scopolamine injection into the bilateral amygdala of mice suggested that the site of action for scopolamine to cause antero- grade amnesia is the ...

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Membrane Potential Dynamics of Hippocampal Neurons During Ripples in Awake Mice

Membrane Potential Dynamics of Hippocampal Neurons During Ripples in Awake Mice

... Figure 23: Fluctuations in pupil diameter during LIA are reflected in membrane potential fluctuations of individual neurons (A) Example of correlated changes in pupil diameter, LFPs, and subthreshold activity ...

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Effects of [beta] amyloid, transferrin and aluminum on cultured hippocampal neurons

Effects of [beta] amyloid, transferrin and aluminum on cultured hippocampal neurons

... above 1X the normal MN2 concentration, neuronal survival in medium containing transferrin or sodium selenite was significantly enhanced compared to neurons grown in non-supplemented medi[r] ...

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An anti-coagulation agent Futhan preferentially targets GABA(A) receptors in lungepithelia: implication in treating asthma

An anti-coagulation agent Futhan preferentially targets GABA(A) receptors in lungepithelia: implication in treating asthma

... cultured hippocampal neurons (left) and in lung A549 cells ...in hippocampal neurons (n = 9) and ...in neurons and in A549 cells, ...

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β-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network

β-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network

... that neurons affected in AD follow a dying-back pattern of degeneration, where such loss of axonal integrity precede somatic cell death and has a profound effect on neuronal network ...of neurons and its ...

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FcγRIIb mediates amyloid β neurotoxicity and memory impairment in Alzheimer’s disease

FcγRIIb mediates amyloid β neurotoxicity and memory impairment in Alzheimer’s disease

... the hippocampal regions of the AD patients, while the level of NeuN was slightly reduced compared with normal control or mild cognitive impairment (MCI) patients (Figure 1, A and B, and Supplemental Table ...

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The highly selective cyclooxygenase-2 inhibitor DFU is neuroprotective when given several hours after transient cerebral ischemia in gerbils

The highly selective cyclooxygenase-2 inhibitor DFU is neuroprotective when given several hours after transient cerebral ischemia in gerbils

... CA1 neurons following 30 min of global ischemia in rats [18], to attenuate white matter damage in chronic cerebral ischemia [23] and to reduce ischemic photothrombotic brain injury in rats ...CA1 ...

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Dexmedetomidine reduces the neuronal apoptosis related to cardiopulmonary bypass by inhibiting activation of the JAK2–STAT3 pathway

Dexmedetomidine reduces the neuronal apoptosis related to cardiopulmonary bypass by inhibiting activation of the JAK2–STAT3 pathway

... of hippocampal neurons and the cortex region, and apoptosis of hippocampus and cortex in group H was significantly decreased compared with group L (Figures 3 and ...

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Characterization of Cognitive Impairment in Type 2 Diabetic Rats

Characterization of Cognitive Impairment in Type 2 Diabetic Rats

... in hippocampal Ach ...and hippocampal slices suggesting neuroinflammatory ...of hippocampal neurons at CA1 and CA3 region in the diabetic rats as compared with healthy ...for ...

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