Hippocampal Slices
Involvement of cellular metabolism in age-related LTP modifications in rat hippocampal slices
... The hippocampal slices of each rat were divided into ten experimental groups (Table ...where hippocampal slices were fixed after brain preparation, without any exogenous ...
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The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices : evidence for the rapid depletion of cellular ATP during electrographic seizures
... Using hippocampal slices as a model of the post-traumatic, post-ischaemic brain (Hossmann 2008) we previously showed that providing slices with the ATP precursors ribose and adenine (RibAde) resulted ...
12
Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice
... 7 slices from adult mice (red diamonds) and 11 slices from aged mice (black ...for slices from adult mice (red bars) and aged mice (black ...between slices from adult and aged is given as * , ...
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Original Article Dexmedetomidine inhibits epileptiform activity in rat hippocampal slices
... produced by high-potassium-concentration- induced epileptiform activity in the CA3 region of rat hippocampal slices [21]. This further sug- gests that the mechanism of the anticonvul- sant action of ...
8
beta Hydroxybutyrate fuels synaptic function during development Histological and physiological evidence in rat hippocampal slices
... brain slices from neonatal rats, ketone bodies are more efficient sources of acetyl-CoA than glucose ...in hippocampal slices prepared from non- precocial animals at several developmental ...
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Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr 1 in rat hippocampal slices
... Conclusions: Our study shows that clinically relevant concentrations of propofol induce c-Fos and down regulated Egr-1 expression via an MAPK/ERK mediated pathway. We demonstrated that propofol induces a time and dose ...
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A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices
... microglia, hippocampal slices were stained with Alexa Fluor 488 conjugated fluorescent Griffonia simplicifolia isolectin IB 4 (Molecular Probes, Eugene, ...staining slices were fixed with 4% parafor- ...
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GABA-mediated inhibitory postsynaptic currents recorded in rat hippocampal slices using intracellular and patch clamp recording techniques
... or hippocampal slices it is possible to stimulate a visually identified interneurone extracellularly, while recor ding from a cell to which it is synaptically ...
118
Some Biochemical Changes of Rat Hippocampal Slices under the Long term Creatine Intraperitoneal Supplementation
... To gain a deeper understanding of the changes resulting from supplementation of Cr into non-aggressive animals, we compared some behavioral and biochemical characteristics of Cr-treated [r] ...
7
Administering Copper Blocks CA1 Neuron Hyper Excitability in Rat Hippocampal Slices
... We have recently shown that copper sulfate at concentration as low as 10 µM can partially reduce neuronal field potentials FP [12] and suppress LTP a form of persistent synaptic voltage [r] ...
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Interactive Effects of Exercise, Sex Hormones, and Transient Congenital Hypothyroidism on Long-Term Potentiation in Hippocampal Slices of Rat Offspring
... The current study showed that hypothyroidism during the development differentially affects males and females with regards to hippocampal functions during adult- hood; thus, it has some long-term gender-specific ...
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Slice orientation and muscarinic acetylcholine receptor activation determine the involvement of N-methyl D-aspartate receptor subunit GluN2B in hippocampal area CA1 long-term depression
... of hippocampal slices that had been sub- ject to scopolamine or control treatments we found that the ratio of RasGRF1 to GluN2B in the immunoprecipi- tate was significantly increased in the scopolamine con- ...
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Leptin inhibits 4 aminopyridine– and pentylenetetrazole induced seizures and AMPAR mediated synaptic transmission in rodents
... frequent upon coinjection of 4-aminopyridine and leptin. In mice, intranasal administration of leptin pro- duced elevated brain and serum leptin levels and delayed the onset of chemical convulsant pentylenetetrazole- ...
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PubMedCentral-PMC4844565.pdf
... Our study provides an explanation for the negative aspect of NaF in that an exposure of the chemical to hippocampal slices induces a dramatic volume reduction. It might be related with an activity of VRAC ...
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A study of long-term potentiation in transgenic mice over-expressing mutant forms of both amyloid precursor protein and presenilin-1
... of hippocampal slices have been studied during ageing of a double transgenic mouse strain relevant to early-onset familial Alzheimer's disease ...preparing slices from 14 month old animals in ...
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Insulin Age Dependently Modulates Synaptic Transmission and AMPA Receptor Trafficking in Region CA1 of the Rat Hippocampus
... in hippocampal memory and learning processes has become better appreciated ...on hippocampal-dependent tasks [6] [7], the molecular effects of insulin in the hippocampus have been largely ...in ...
15
TRPA1 channels promote astrocytic Ca2+ hyperactivity and synaptic dysfunction mediated by oligomeric forms of amyloid-β peptide
... in hippocampal slices [40] and in vivo [12] but here we showed a peculiar rapid action on compartmentalized calcium activity, activating a membrane Ca 2+ permeable ...
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Examinations into the Calcium Hypothesis of Alzheimer's Disease
... and hippocampal slices from mutant PS1 expressing ...enhanced hippocampal ryanodine receptor protein level, enhanced hippocampal synaptic potentiation, and constitutive activation of the ...
172
Nervous System and Gastrointestinal Effects of the Insecticide Esfenvalerate on the Rat: An Ex Vivo Study
... and hippocampal brain slices, while gastrointestinal effects were examined by analyzing the motility and excitabili- ty of isolated ileum ...brain slices originating from esfenvalerate-treated ...
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Transient extracellular application of gold nanostars increases hippocampal neuronal activity
... gold nanostars using a silver-seed mediated method we recently developed [6]. We applied the nanoparticles to mouse hippocampal slices while recording the action potential activity of neurons in the CA3 ...
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