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HIV-1 transmission

Human immunodeficiency virus 1 (HIV 1) gp120 superantigen binding serum antibodies  A host factor in homosexual HIV 1 transmission

Human immunodeficiency virus 1 (HIV 1) gp120 superantigen binding serum antibodies A host factor in homosexual HIV 1 transmission

... HIV-1 gp120 is an immunoglobulin superantigen which can bind to preimmune serum Ig. We hypothesize that levels of such preimmune antibodies vary in the population and might affect host resistance or ...

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HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission

HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission

... in HIV-1 transmission (30, 32, 38, 40, 42, ...that HIV-1 with more oligomannose and less complex Env glycans is more efficiently captured by MoDCs and displays enhanced trans- infection ...

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Memory CD4+ T Cells Are the Earliest Detectable Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells in the Female Genital Mucosal Tissue during HIV-1 Transmission in an Organ Culture System

Memory CD4+ T Cells Are the Earliest Detectable Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells in the Female Genital Mucosal Tissue during HIV-1 Transmission in an Organ Culture System

... Viral transmission was monitored by measuring HIV-1 infectivity in the supernatant from the bot- tom well by the cMAGI ...of transmission was calculated by the number of blue-stained cMAGI ...

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Dendritic cell mediated HIV 1 transmission to T cells of LAD 1 patients is impaired due to the defect in LFA 1

Dendritic cell mediated HIV 1 transmission to T cells of LAD 1 patients is impaired due to the defect in LFA 1

... mediated HIV-1 transmission. Although LFA-1 of this patient is able to recognize its ligand, no high avidity/ affinity binding to ICAM-1 is taking ...for HIV-1 ...

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TNF α and TLR agonists increase susceptibility to HIV 1 transmission by human Langerhans cells ex vivo

TNF α and TLR agonists increase susceptibility to HIV 1 transmission by human Langerhans cells ex vivo

... enhanced transmission in all donors ...of HIV-1 transmission (Supplemental Figure 8), demonstrating that Pam3CSK4 increased transmission independent of ...replication-defective ...

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Trans dominant cellular inhibition of DC SIGN mediated HIV 1 transmission

Trans dominant cellular inhibition of DC SIGN mediated HIV 1 transmission

... in HIV-1 transmission ...whether HIV-1 transmission could be detected when Raji/DC-SIGN or Raji cells were mixed in equal proportion with K562/DC-SIGN or K562 ...that ...

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The HIV 1 transmission bottleneck

The HIV 1 transmission bottleneck

... for HIV-1 to gain ...abundant HIV-1 target cells in the rectal ...of HIV-1 transmission in males are the inner foreskin, tissue directly underneath the foreskin, and the ...

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The inference of HIV 1 transmission direction between HIV 1 positive couples based on the sequences of HIV 1 quasi species

The inference of HIV 1 transmission direction between HIV 1 positive couples based on the sequences of HIV 1 quasi species

... of HIV-1 in vivo experienced pressures from many aspects such as host’s immune system, antiretroviral therapy, which will lead to the loss of HIV diversity in vivo ...of HIV-1 positive ...

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HIV-1 transmission and survival according to feeding options in infants born to HIV-infected women in Yaoundé, Cameroon

HIV-1 transmission and survival according to feeding options in infants born to HIV-infected women in Yaoundé, Cameroon

... monitoring HIV-exposed infants until completion of PMTCT-cascade-care, retention in care is concerning, with persistent risks of HIV-vertical transmis- sion around 24 months of infant age (above 8% ...

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Determinants Of Hiv-1 Transmission Fitness

Determinants Of Hiv-1 Transmission Fitness

... eight HIV-1 donor and recipient transmission pairs representing the most prevalent subtypes (B and ...various HIV-1 constructs to specifically disrupt their Vpu-mediated tetherin ...

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Tracing HIV 1 transmission: envelope traits of HIV 1 transmitter and recipient pairs

Tracing HIV 1 transmission: envelope traits of HIV 1 transmitter and recipient pairs

... an HIV-1 backbone plasmid carrying the luciferase reporter gene (pNLluc- AM, [77]) and the respective env plasmid at a ratio of 3:1 using polyethylenimine (PEI) as described ...

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Lactoferrin Prevents Dendritic Cell-Mediated Human Immunodeficiency Virus Type 1 Transmission by Blocking the DC-SIGN—gp120 Interaction

Lactoferrin Prevents Dendritic Cell-Mediated Human Immunodeficiency Virus Type 1 Transmission by Blocking the DC-SIGN—gp120 Interaction

... of HIV-1 to the CD4 receptor (27, 32), and neg- atively charged macromolecules can inhibit HIV-1 by binding to the positively charged V3 loop of gp120 ...inhibits HIV-1 replica- ...

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Maternal but Not Infant Anti HIV 1 Neutralizing Antibody Response Associates with Enhanced Transmission and Infant Morbidity

Maternal but Not Infant Anti HIV 1 Neutralizing Antibody Response Associates with Enhanced Transmission and Infant Morbidity

... although HIV-1-specific nAbs were efficiently transferred from mother to infant; they were not a correlate of protection from HIV-1 breast milk ...Surprisingly, HIV-1-infected TMs ...

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Selective transmission of R5 HIV 1 variants: where is the gatekeeper?

Selective transmission of R5 HIV 1 variants: where is the gatekeeper?

... cells HIV-1 uses CD4 and a ...X4 HIV-1). Although both R5 and X4 HIV-1 variants are present in body fluids (semen, blood, cervicovaginal and rectal secretions), R5 ...

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Pseudotyping of HIV-1 with Human T-Lymphotropic Virus 1 (HTLV-1) Envelope Glycoprotein during HIV-1–HTLV-1 Coinfection Facilitates Direct HIV-1 Infection of Female Genital Epithelial Cells: Implications for Sexual Transmission of HIV-1

Pseudotyping of HIV-1 with Human T-Lymphotropic Virus 1 (HTLV-1) Envelope Glycoprotein during HIV-1–HTLV-1 Coinfection Facilitates Direct HIV-1 Infection of Female Genital Epithelial Cells: Implications for Sexual Transmission of HIV-1

... of HIV-1, the global AIDS pandemic continues to expand in some regions of the ...sexual transmission of HIV-1 is the primary route of HIV-1 dissemination worldwide ...

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Diversity of the Human Immunodeficiency Virus Type 1 (HIV-1) env Sequence after Vertical Transmission in Mother-Child Pairs Infected with HIV-1 Subtype A

Diversity of the Human Immunodeficiency Virus Type 1 (HIV-1) env Sequence after Vertical Transmission in Mother-Child Pairs Infected with HIV-1 Subtype A

... type 1 (HIV-1) transmission have been described, the mechanism of mother-to-child transmission is still ...the transmission remains ...utero transmission and after ...

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Acyclovir and Transmission of HIV-1 from Persons Infected with HIV-1 and HSV-2

Acyclovir and Transmission of HIV-1 from Persons Infected with HIV-1 and HSV-2

... (linked transmission) or likely to have been acquired from someone other than the person’s study partner (unlinked trans- mission); the classification was based on the se- quencing of plasma samples from the ...

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Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1

Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1

... to HIV-1-infected mothers in resource-limited areas where replacement feeding is unsafe and impractical are re- peatedly exposed to HIV-1 throughout ...contract HIV-1 ...

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HIV 1 cell to cell transmission and broadly neutralizing antibodies

HIV 1 cell to cell transmission and broadly neutralizing antibodies

... cell-to-cell HIV-1 transmission ...against HIV-1 cell-to-cell transmission ...where HIV-1 virions present in VCCs are protected from recognition by bNAbs, even if ...

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Diminished transmission of drug resistant HIV 1 variants with reduced replication capacity in a human transmission model

Diminished transmission of drug resistant HIV 1 variants with reduced replication capacity in a human transmission model

... Sexual HIV transmission is an inefficient process dur- ing which a limited number of virions initiate an infec- tion in a new host, resulting in a severe transmission bottleneck ...of HIV, it ...

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