HL-60 Cells
Activation of NQO1 in NQO1*2 polymorphic human leukemic HL-60 cells by diet-derived sulforaphane
... leukemic HL-60 cells harboring the polymorphic NQO1*2 variant can be reactivated by physiologically achievable doses of SFN via a mechanism involving the activation of Nrf2- mediated transcription ...
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Stimulation by leukotriene D4 of increases in the cytosolic concentration of calcium in dimethylsulfoxide differentiated HL 60 cells
... responses of [Ca+2]i to LTC4 and LTD4, and the finding that the serine-borate inhibitor of conversion of LTC4 to LTD4 suppressed concurrently both LTC4-induced rises in [Ca+2]i and increases in adherence to Sephadex G-25 ...
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Pyrrolidine Dithiocarbamate (PDTC) Attenuates Luteolin Induced Apoptosis in Human Leukemia HL 60 Cells
... in HL-60 human leukemia ...in HL-60 cells; PDTC could interfere with luteolin’s ability to cleave poly(ADP-ribose)-polymerase (PARP) and DNA fragmentation of factor-45 ...the ...
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Dose Dependent Biological Effects of Idarubicin in HL-60 Cells: Alterations of the Cell-Cycle and Apoptosis
... the cells and induce changes in cell ...live cells accumulate in S phase of cell-cycle, af- ter 24 hours we observed arrest in G 2 ...the cells did not proliferate during 72 ...the cells ...
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Influence of temperature rise by 2.5°C on the increase of apoptosis of HL-60 cells treated with busulfan
... of HL-60 cells at 37°C and ...apoptotic cells (Annexin V+/PI−) consisted of 63% of both apoptotic ...totic cells were in the early phase of apoptosis: 82% at ...
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Up-regulation of p21 and TNF-α is mediated in lycorine-induced death of HL-60 cells
... When HL-60 cells were treated with different concentration of lycorine, the expression of p21 and TNF- a was up-regulated in a concentration-dependent manner as shown by real-time quantitative ...
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Vitamin D3 potentiates the antitumorigenic effects of arsenic trioxide in human leukemia (HL-60) cells
... The HL-60 promyelocytic leukemia cell line ...blood cells of a 36-year old Caucasian fe- male with acute promyelocytic leukemia ...The HL- 60 cells grow as a suspension ...
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<p>Notopterol-induced apoptosis and differentiation in human acute myeloid leukemia HL-60 cells</p>
... for HL- 60 ...in HL-60 ...induced HL-60 cell apoptosis partly through the mitochon- drial intrinsic ...in HL-60 ...notopterol-treated HL-60 ...
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Basic Mechanisms of Arsenic Trioxide (ATO)-Induced Apoptosis in Human Leukemia (HL-60) Cells
... in HL-60 promyelocytic leukemia ...of HL-60 cells in a dose-dependent manner, at least in part, through activation of ...positive cells (apoptotic cells) increases ...
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Development of an Opsonophagocytic Killing Assay Using HL-60 Cells for Detection of Functional Antibodies against Streptococcus pyogenes
... in HL-60 cells plus complement to select for bacteria that were fully resistant to phagocytic ...by HL-60 cells, fewer bacteria were added to the test mixtures than had been used ...
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Cellular glutathione levels in HL-60 cells during respiratory burst are not correlated with ultra-weak photon emission
... in HL-60 cells during respiratory ...entiated cells, glutathione (GS-NEM and total GSH) levels were sig- nificantly decreased, whereas the levels of GSSG increased significantly, causing a ...
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Effect of N’ Acetylindirubin on Proliferation, Apoptosis and Cell Cycle in Acute Myeloid Leukemia HL 60 Cells
... Acute promyelocytic leukemia (APL) is a severe type of acute leukemia and the prognosis of patients was poor. Indirubin is the active constituent of the traditional Chinese medicine qingdai and an indoline anti-tumor ...
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Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL 60 cells
... DMSO-differentiated HL- 60 cells with compactin produced a concentration-dependent inhibition of O2- formation in response to FMLP or phorbol myristate ...the HL-60 cells into a ...
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Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells
... differentiated HL-60 cells to model human neutrophils as these dHL60 cells can be modified ...differentiated HL-60 cells have many features that mimic mature human neu- ...
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Antioxidant attenuation of ROS involved cytotoxicity induced by Paraquat on HL 60 cells
... and humans which are refractory to treatment [38-42]. As it used worldwide in agriculture, the toxicities of PQ on its untargeted organism are supposed to be well-administered. A wide spectrum of investigations pivoting ...
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Lp16-PSP, A Member of YjgF/YER057c/UK114 Protein Family Induces Apoptosis and p21WAF1/CIP1 Mediated G1 Cell Cycle Arrest in Human Acute Promyelocytic Leukemia (APL) HL-60 Cells
... acute promyeloid leukemia (HL-60 cells) as model cancer to further investigate the potential molecular.. 84.[r] ...
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Electroporation of adherent cells with low sample volumes on a microscope stage
... living cells are powerful techniques for investigating intracellular molecular ...adherent cells directly, without removing them from the ...adherent cells while observing them on the stage of an ...
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Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety
... in HL-60 cells (Supp ...in HL-60 cells treated with DHA and ...that HL- 60 cells did not express Bcl-xL and that decreasing the Mcl-1 protein level could ...
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Hydrogen peroxide (H2O2) induces leukemic but not normal hematopoietic cell death in a dose-dependent manner
... ture cells. For mouse stem cells (m-HSC) and progeni- tor cells (m-HPC), the following antibodies were used: Ter119 (Ly-76), Mac-1 (myM1/70), Gr-1 (RB6-8C5), B220 (RA3-6B2), CD3 (145-2C11) and Flk-2 ...
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Gamma interferon induces monocytoid differentiation in the HL 60 cell line
... monocytoid differentiation. These included induction of alpha-naphthyl acetate esterase, increased cell size, and a decrease in azurophilic granules. The gamma-IFN dose dependency and time course of the effect on antigen ...
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