HL-60 cells that have been induced to differentiate with DMSO
Propagation of granulocytic Ehrlichia spp from human and equine sources in HL 60 cells induced to differentiate into functional granulocytes
... of cells of myelocytic origin as ...has been reported recently that the HGE pathogen can be propagated in the HL-60 promyelocytic leukemia cell line ...(5). HL-60 cells ...
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Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells
... HL60 cells are commonly used as a model system for neutrophil migration ...neutrophils have a short half-life in vitro and are terminally ...mature cells such as neutrophils using cur- rent ...
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Regulation of phospholipase D and primary granule secretion by P2 purinergic and chemotactic peptide receptor agonists is induced during granulocytic differentiation of HL 60 cells
... documented ability of ATP to stimulate large increases in polyphosphoinositide hydrolysis and Ca2+ mobilization. Conversely, within 1 d after induction of granulocytic differentiation by dibutyryl cAMP, both ATP and FMLP ...
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Transcriptional and posttranscriptional regulation of macrophage specific colony stimulating factor gene expression by tumor necrosis factor Involvement of arachidonic acid metabolites
... uninduced HL-60 cells, reached maximal levels by 3 h of exposure to TNF, and returned to that of control cells by 24 ...TNF- induced CSF-1 mRNA ...
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Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety
... in HL-60 cells (Supp ...in HL-60 cells treated with DHA and ...that HL- 60 cells did not express Bcl-xL and that decreasing the Mcl-1 protein level could ...
15
Stimulation by leukotriene D4 of increases in the cytosolic concentration of calcium in dimethylsulfoxide differentiated HL 60 cells
... responses of [Ca+2]i to LTC4 and LTD4, and the finding that the serine-borate inhibitor of conversion of LTC4 to LTD4 suppressed concurrently both LTC4-induced rises in [Ca+2]i and increases in adherence to ...
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Metabolomics profiles delineate uridine deficiency contributes to mitochondria-mediated apoptosis induced by celastrol in human acute promyelocytic leukemia cells
... to previous study [25]. Finally, 39 metabolites were retained (Supplementary Table S1). After mapping these metabolites into their respective biochemical pathways as outlined in the Kyoto Encyclopedia of Genes and ...
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<p>Notopterol-induced apoptosis and differentiation in human acute myeloid leukemia HL-60 cells</p>
... protects cells from G1 phase blockade, eventually leading to the activation of CDK2/Cyclin E ...efforts have focused on the search of agents that can enhance ATRA ’ s effect on AML ...when cells were ...
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By activating Fas/ceramide synthase 6/p38 kinase in lipid rafts, Stichoposide D inhibits growth of leukemia xenografts
... investigators have recently focused on the development of anticancer agents from natural marine ...to have a wide spectrum of biological activities, including antifungal, antitumor, hemolytic, and ...
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Extracellular adenosine triphosphate activates calcium mobilization in human phagocytic leukocytes and neutrophil/monocyte progenitor cells
... progenitor cells as immature as myeloblasts, but not in ...the HL-60 promyelocytic cell line have indicated these Ca2+-mobilizing effects of ATP can ...
11
Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL 60 cells
... of DMSO-differentiated HL- 60 cells with compactin produced a concentration-dependent inhibition of O2- formation in response to FMLP or phorbol myristate ...the HL-60 ...
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Immunocytochemical Study on Microtubule Reorganization in HL-60 Leukemia Cells Undergoing Apoptosis
... neoplastic cells undergoing apoptosis induced by cytotoxic ...was induced in the human leukemia cells (HL-60) by treatment with 1 µM of all-trans retinoic acid over a 5-day ...in ...
6
Downregulation of PDIA3 inhibits proliferation and invasion of human acute myeloid leukemia cells
... controls. HL-60 and HEL cell lines were further investigated for high expression of ...AML HL-60 and HEL cells. PDIA3 siRNA also induced apoptosis of AML ...
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Antiproliferative activity and induction of apoptosis by Annona muricata (Annonaceae) extract on human cancer cells
... extracts-induced HL-60 cell ...arrest cells in the G0/G1 phase and in- hibit cell ...muricata induced apoptosis in HL-60 tumor cells in ...
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Original Article JARID1B deletion induced apoptosis in Jeko-1 and HL-60 cell lines
... stained cells. According to color density, non-stained cells were scored as 0, slightly stained were 1, inter- mediate-stained were 2, strongly stained were ...positive cells was < 25%, 25%-50%, ...
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Up-regulation of p21 and TNF-α is mediated in lycorine-induced death of HL-60 cells
... When HL-60 cells were treated with different concentration of lycorine, the expression of p21 and TNF- a was up-regulated in a concentration-dependent manner as shown by real-time quantitative ...
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Basic Mechanisms of Arsenic Trioxide (ATO)-Induced Apoptosis in Human Leukemia (HL-60) Cells
... in HL-60 promye- locytic leukemia ...in HL-60 promyelocytic leukemia cells in a dose-dependent manner, showing an increase expression of annexin positive cells in ATO-treated ...
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Antioxidant attenuation of ROS involved cytotoxicity induced by Paraquat on HL 60 cells
... has been sprayed in the ...had been reported over the past few decades ...Clara cells and alveolar type I and II epithelial cells ...papers have suggested a possible link to ...
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The Association Between Oxidative Stress, Cellular Differentiation And Galectins In Human Promyelocytic Leukemia Cells (HL-60)
... activation induced by galectin-9, indicating a role of galectin-9 working both up- and down-stream of this redox signaling pathway (Kobayashi et ...has been reported in few molecular processes regarding ...
135
Pyrrolidine Dithiocarbamate (PDTC) Attenuates Luteolin Induced Apoptosis in Human Leukemia HL 60 Cells
... luteolin-treated HL-60 cells (Fig- ure 3). Previously we have found that PDTC modulated the phosphorylation of Akt and reduces the activity of caspase-9, thereby inhibiting ...
7