HLA Allele
HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs
... explore HLA allele frequencies and their association with SJS/TEN according to culprit drugs in ...of HLA typing test from August 2005 to July ...of HLA-B*58:01, HLA-B*44:03, ...
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HLA-B*57 Micropolymorphism Shapes HLA Allele-Specific Epitope Immunogenicity, Selection Pressure, and HIV Immune Control
... identify HLA and OLP ...of HLA- B*5702, HLA-B*5703, and ...4-digit HLA alleles ob- served in the cohort and added the most significant HLA allele to the decision ...that ...
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HLA allele frequencies in Iranian opticospinal multiple sclerosis patients——HLA in Opticospinal MS
... gene HLA-DRB1 ...the HLA DRB1*1501 allele ...with HLA-DRB1 and the form without this association, onclusively demonstrates that MS is immu- nogenetically ...
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Association of erythrocyte sedimentation rate and C-reactive protein and clinical findings with HLA-DQ8 allele in Rheumatoid Arthritis patients
... auto-antigens. HLA- DRB1*0401 allele has a significant relationship with RA ...this allele is different in various populations Material and Methods ― 70 patients and 70 healthy controls were analyzed ...
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Derivation of HLA types from shotgun sequence datasets
... reference allele sequences, and integrating all of these data in a manner that maximally informs HLA ...for HLA allele prediction from next- generation shotgun sequence ...tantly, HLA ...
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Resolution of Ambiguous HLA Genotyping in Korean by Multi Group Specific Sequence Based Typing
... for HLA alleles uncommon in Korean. Actually, ambiguous HLA allele combinations analyzed in our study showed lower expected genotype frequencies for populations other than Korean (Table ...probable ...
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HLA-Cw*04 allele associated with nevirapine-induced rash in HIV-infected Thai patients
... that HLA-Cw*08 is associated with NVP ...that HLA-Cw*08 and/or HLA-B*14(65) is associated with NVP hypersensitivity ...of HLA-B*14 is nearly 0% in Japan. On the other hand, the frequency of ...
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Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
... of HLA mutation across tumors and showed that such mutations occurred preferentially in tumors with high mutation burden and under strong pressure by the immune system as evi- denced by high levels of CD8+ T cell ...
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HLA B27 allele types in homogeneous groups of juvenile idiopathic arthritis patients in Latvia
... individual HLA allele association with choice of therapeutical drugs, ...e.g. HLA B27 positive heel enthesitis treatment with Adalilumab [36] or HLA DR3 positive rheumatoid arthritis treatment ...
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HLAProfiler utilizes k-mer profiles to improve HLA calling accuracy for rare and common alleles in RNA-seq data
... the HLA genes replaced with specific HLA alleles unique to each ...subject. HLA allele se- quences were obtained from the IMGT/HLA database (v24) ...of HLA reads roughly matched ...
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Molecular footprints reveal the impact of the protective HLA A*03 allele in hepatitis C virus infection
... Escape mutations may also provide critical information about the nature of the T cell response within a given population. Significant T cell responses within a population will result in selection pressure and results in ...
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Structural insights of CD4+ Gag epitopes and HLA DRB1*10 allele complexes
... of HLA-DRB1*10 Allele-Gag peptides would be helpful indentifying the Gag based HIV vaccine construct ...DRB1*10 allele since the stable hydrogen bonding and epitope’s occupancy on binding groove of ...
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Allele Frequencies of HLA-A, B and DRB1 among People of Fars Ethnicity Living in Tehran
... of HLA allele frequencies has been of some help in estimation of donor size, complete data of both MHC class I and class II allele frequencies in various Iranian ethnic groups, optimally obtained by ...
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Diversity and Frequencies of HLA Class I and Class II Genes of an East African Population
... the HLA class I and II genes [7] and comprehensive analysis of allele frequencies of more than 2000 women from Kenya, eastern Tanzania and southern Uganda around lake ...II HLA allele ...
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Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome
... In this study we examined the interaction of the pro- inflammatory P2X7 receptor in the pathogenesis of Ro±La autoantibody-positive pSS (seropositive pSS) in two cohorts. The primary focus was on the P2RX7 1405G ...
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Associations between the HLA Apolymorphism and the clinical manifestations of Behcet's disease
... fact, HLA-B*51, the most prominent susceptibility gene [4,5], has been estimated to increase the relative risk of BD by 20% in the siblings of affected individuals [6], which suggests that other susceptibility ...
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Evaluation of six CTLA 4 polymorphisms in high risk melanoma patients receiving adjuvant interferon therapy in the He13A/98 multicenter trial
... been rigorously prospectively characterized, assumes that the predominant effect of CTLA-4 polymorphisms is upon T-cell responsiveness. The CT 60AA allele is associated with increased circulating levels of soluble ...
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Tracking Human Migrations By The Analysis of The Distribution of Hla Dqb1* Allele of Indian and African Populations
... The HLA system is highly polymorphic and commonly used as a marker to understandthe core genetic aspects of human population such as stratification, human migration, predisposition to diseases and tissue ...
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The importance of HLA DRB1 gene allele to clinical features and disability in patients with multiple sclerosis in Lithuania
... between HLA complex genes and the course of MS remains unclear. HLA DRB1*04 was found to be more common among patients with the progressive forms of the disease ...the HLA DRB1*15 allele ...
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HLA Class Ii Allele and Haplotype Associations with Type 1 Diabetes in Jeddah, Saudi Arabia
... The study population was diagnosed in the King Abdulaziz University Hospital's pediatric endocrinology clinic with 96 T1D subjects with disease onset in 12 to 18 years of age. Of the T1D patients, 50 were female and 46 ...
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