HLA antibodies
Quantitation of HLA Proteins Incorporated by Human Immunodeficiency Virus Type 1 and Assessment of Neutralizing Activity of Anti-HLA Antibodies
... All plasma samples were tested for neutralization activity at a 1/10 dilution. Since HIV-1 inhibition due to undefined plasma components may be seen if a lesser dilution of plasma is used, IgG antibodies from ...
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Differential effects of donor-specific HLA antibodies in living versus deceased donor transplant
... This multicenter study included all 6097 kidney transplants per- formed between January 1995 and December 2005 in all Dutch transplant centers. Patients were primarily white. In all cases, the T cell CDC- XM with current ...
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A subset of anti-HLA antibodies induces Fc gamma RIIa-dependent platelet activation
... Figure 6. Phagocytosis of platelets opsonized by HLA monoclonal antibodies and the effect of FcγRIIa-dependent signaling. Platelets were incubated with 10 mg/mL WIM8E5, SN607D8 or SN230G6 in the presence or ...
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Prevalence of pre-transplant anti-HLA antibodies and their impact on outcomes in lung transplant recipients
... PGD is considered multifactorial and could include the in- flammatory response associated with anti-HLA. Hadjilia- dis et al. reported that an elevated pre-transplant PRA in lung transplant recipients is ...
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A glow of HLA typing in organ transplantation
... Regarding antibodies screening was done to avoid hyperacute rejection, it is very important to identify re- cipient anti-HLA antibodies to antigens expressed on donor with blood cells ...such ...
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Therapeutic plasma exchange in heart transplantation: role of coagulation assessment with thromboelastometry
... (HLA) antibodies from the bloodstream, allowing critically ill heart transplant recipients to receive a donor organ with less wait time, and reducing the risk of acute organ ...
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Current perspectives on antibody-mediated rejection after lung transplantation
... of HLA antibodies before ...donor’s HLA type, cross- match results can be predicted accurately before donor organ ...of HLA incompatible transplants; as a result, hyperacute rejection has ...
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Survey of platelet glycoprotein specific antibodies and HLA class 1 antibodies in a cross section of Nigerian multiparous women
... and HLA antibodies as observed in this ...these antibodies showed a very significant association with ...the antibodies once developed can persist in their circulation for a long ...
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Role of Antibodies in Protection Elicited by Active Vaccination with Genetically Inactivated Alpha Hemolysin in a Mouse Model of Staphylococcus aureus Skin and Soft Tissue Infections
... inactivated Hla vaccine in a murine SSTI model is likely similarly ...that antibodies mediate protection in this SSTI model, the specific mechanism of how antibodies against a se- creted toxin target ...
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Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin
... anti-Hla antibodies neutralize Hla toxicity, it is not surprising that Hla is considered one of the most promising ...of Hla were purified as GST fusion proteins and were used in the ...
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Detection of HLA class I-specific antibodies by the QuikScreen enzyme-linked immunosorbent assay.
... different HLA antigens present in the preparation of soluble antigens should not be equal but rather should be proportional to their frequencies in the population from which the platelets were ...the HLA-C ...
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Comprehensive Analysis of HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 Loci and Squamous Cell Cervical Cancer Risk
... decreased risks associated with allele combinations containing only class I alleles, such as A*0201-B*1501 (OR 0.4, 95% CI0.2-0.7) and B*0801-Cw*0701 (OR 0.7, 95% CI 0.5-0.9). In this study, B*4402 was found to be a ...
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Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases
... between HLA allelic sub-types and HPV type-specific peptides, suggesting that HLA recognition is HPV type-specific ...higher HLA class I expression levels as compared to ...of HLA expression ...
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Novel treatment of severe combined immunodeficiency utilizing ex-vivo T-cell depleted haploidentical hematopoietic stem cell transplantation and CD45RA+ depleted donor lymphocyte infusions
... Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative treatment available for severe combined immunodeficiency (SCID); although, there is a high incidence of severe infections and an ...
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Correlation between HLA haplotypes and the development of antidrug antibodies in a cohort of patients with rheumatic diseases
... HLA-A, HLA-B, HLA-C, HLA-DR β 1, and HLA-DQ β 1 were genotyped by means of the hybridization of sequence-specific oligonucleotide (SSO) probes immobilized on microspheres and amplified ...
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The role of platelet microparticles in the production of antibodies from B lymphocytes against HLA-DR antigen in vitro
... allow antibodies to be bound to the target ...the antibodies of T, NK, and monocyte cell surface were absorbed into the wall of the falcon tube under the magnetic ...and HLA-DR antigen in RPMI 1640 ...
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MHC restricted fratricide of human lymphocytes expressing survivin specific transgenic T cell receptors
... by HLA-A2–restricted fratricide that occurred due to survivin expression in lympho- cytes, which created ligands for Tg-TCR ...in HLA-A2–mismatched stem cell ...from HLA-A2 ...
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Dendritic cells and the promise of antigen specific therapy in rheumatoid arthritis
... given HLA-restricted peptide ...with HLA-DRB1*0405 ...because HLA-DRB1*04 alleles were not subtyped to allow comparison of sequences associated with a single MHC ...
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Transplantation of MHC-mismatched mouse embryonic stem cell-derived thymic epithelial progenitors and MHC-matched bone marrow prevents autoimmune diabetes
... Abs: Antibodies; BM: Bone marrow; BMT: BM transplantation; DE: Definitive endoderm; EAE: Experimental autoimmune encephalomyelitis; GVHD: Graft- versus-host disease; HLA: Human leukocyte antigen; Ins2: ...
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