HLA-DPB1
Acute Graft Versus Host Disease due to T lymphocytes recognizing a singel HLA-DPB1*0501 mismatch.
... of HLA-DP–spe- cific T cells in the skin lesions of patients who developed GVHD after semiallogeneic BMT (11, ...other HLA class I and class II incompatibilities were present in addition to the ...
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Acute graft versus host disease due to T lymphocytes recognizing a single HLA DPB1*0501 mismatch
... observations: HLA-DP incompatibility does not significantly influence the risk of acute GVHD (9, 10), yet HLA-DP specific T cells can be isolated from skin bi- opsies at the onset of GVHD each time an ...
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Dissecting Genetic Control of HLA-DPB1 Expression and Its Relation to Structural Mismatch Models in Hematopoietic Stem Cell Transplantation
... Regarding risk prediction by the Expression model and the TCE structural model in HSCT, we show a relatively limited degree of 36.7% concordance in our exemplary cohort, which however was due in the majority of cases to ...
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Further investigation of the role of HLA-DPB1 in adult Hodgkin's disease (HD) suggests an influence on susceptibility to different HD subtypes.
... the HLA class II region, and specifically by alleles at the HLA-DPB1 ...different HLA-DPB1 alleles confer susceptibility to different HD ...type DPB1 alleles in 147 adult HD ...
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Amplified fragment length polymorphism typing of HLA-DPB1 and associations with IDDM and MS
... shared by different DPB1 alleles can be assessed. This approach has been used for other HLA loci. Neutral amino acid residues at amino acid position 57 in DQB1 alleles are associated with IDDM ...
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The HLA DPB1*02:01:02 and DQB1*05:02:01 alleles as possible risk factors for colorectal carcinoma in the Malaysian population
... of HLA class II alleles with ...of HLA class II expression in CRC tissues which ranged from 21% to 55% using the immunohistochemistry method (17, ...of HLA Class II expression is certainly not ...on ...
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Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population.
... the HLA-DPB1 (rs9277535) and HLA-DQB2 (rs7453920) genes with the HBV chronic infection were analyzed in a population from southern ...the HLA-DPB1 (rs9277535) polymorphism is often ...
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Diversity and Frequencies of HLA Class I and Class II Genes of an East African Population
... of HLA class I and class II genes of more than 2000 women from Kenya, eastern Tanzania and southern Uganda around Lake Victoria and analyzed their allele, phenotype and haplotype ...79 HLA-A, 113 ...
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A Novel Variant Marking HLA-DP Expression Levels Predicts Recovery from Hepatitis B Virus Infection
... of HLA-C expression in healthy donors correlate with outcome after HIV infection (28), and a variant in the 3=UTR of HLA-C, which differentially binds a microRNA, accounts in part for the varied expression ...
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The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients
... unknown. HLA association in anti-GBM disease is believed to reflect the ability of certain class II molecules to bind and present peptides derived from the autoantigen to T helper cells ...to ...
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Stability and Expression Levels of HLA-C on the Cell Membrane Modulate HIV-1 Infectivity
... the HLA-C*02, -*05, -*06, -*08, -*12, -*15, and -*16 allotypes as stable and the HLA-C*01, -*03, -*04, -*07, and possibly -*14 allotypes as ...the HLA-C alleles tested for assembly were characterized ...
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Analysis of HLA-A, HLA-B and HLA-DRB1 allelic frequencies in tertiary care from Telangana and Andhra Pradesh
... analyse HLA-A, HLA-B and HLA-DRB1 allelic frequencies among renal transplant recipients and their prospective related and unrelated donors attending Nephrology department at KIMS Hospital, ...for ...
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HLA gene amplification and hybridization analysis of polymorphism HLA matching for bone marrow transplantation of a patient with HLA deficient severe combined immunodeficiency syndrome
... of HLA polymorphism at the level of single amino acid differences; and elimination of a requirement for HLA ...II HLA proteins, polymorphism associated with DR7,w53;DQw2;DRw11a (a split of DR5), w52b ...
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Expression analysis of HLA E and NKG2A and NKG2C receptors points at a role for natural killer function in ankylosing spondylitis
... Twenty-one HLA-B*2705 patients with AS fulfilling the modified New York criteria for the diagnosis of AS (15 men and 6 women, mean age ...12 HLA-B*2705, 12 HLA-B*2709 and 6 HLA-B27-negative ...
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Polymorphisms in the F pocket of HLA B27 subtypes strongly affect assembly, chaperone interactions and heavy chain misfolding
... for HLA-B27 with the V5 tag antibody and immunoblotted for ERp57. HLA-B27-ERp57 conjugates were detected in the ...for HLA-B27 using the V5 ...
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The increased ability to present citrullinated peptides is not unique to HLA SE molecules: arginine to citrulline conversion also enhances peptide affinity for HLA DQ molecules
... of HLA-DQ molecules to present citrullinated ligands has not yet been ...from HLA-DQ8 transgenic mice immunized with collagen type II (CII) respond bet- ter to citrullinated CII than to native CII, which ...
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In vitro lymphocyte proliferation response to therapeutic insulin components Evidence for genetic control by the human major histocompatibility complex
... responded to the following therapeutic insulin components: beef, HLA-DR4; beef and pork, HLA-DR3; beef proinsulin, HLA-BW4, CW2, CW5, DR2, and DR5; protamine, HLA-CW3, CW5, and DR7. The ...
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HLA-DQA1 and HLA-DQB1 in Celiac disease predisposition: practical implications of the HLA molecular typing
... Approximately 90% of celiac subjects present HLA- DQ2 heterodimers, hereafter called DQ2.5, encoded by DQA1*05 and DQB1*02 alleles, which may be inherited together on the same chromosome (cis configuration) or ...
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Varicella-Zoster Virus-Derived Major Histocompatibility Complex Class I-Restricted Peptide Affinity Is a Determining Factor in the HLA Risk Profile for the Development of Postherpetic Neuralgia
... most HLA alleles but was not devoid of ...for HLA-A*02 is then also un- surprising for both VZV IE62 and IE63 in this context, as this is a very common allele (39), and it has been shown that viruses can ...
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Association Between HLA DQBl * 03 and Cervical Intra-epithelial Neoplasia
... analysis of HLA type has shown a significant association between HLA class II, in particular HLA DQB 1 * 03, and cervical cancer but not for.. class I (1).[r] ...
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