HLA-G
Association of HLA-G 14-base pair insertion/deletion polymorphism with breast cancer in Saudi Arabia
... the HLA-G gene has been reported to influence HLA-G protein ...The HLA-G 14-bp polymorphism was typed by PCR in 52 patients with breast cancer and 62 healthy control Saudi ...
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Original Article MicroRNA-148a affects functions of placental trophoblast cells in preeclampsia by regulating HLA-G
... of HLA-G by reducing the protein level of DNMT1. HLA-G is a non-classical HLA- Ib molecule characterized expressed in EVT, and played an important role in establishing a normal ...
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Down-regulation of HLA-G Attenuates Cleavage Rate in Human Triploid Embryos
... Introduction: HLA-G is a major histocompatibility complex (MHC), class Ib mol- ecule that is selectively expressed at the fetal–maternal ...As HLA-G is expressed in human early embryos, it is ...
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Relationship of HLA-G expression and its 14-bp insertion/deletion polymorphism with susceptibility to colorectal cancer
... The allele and genotype frequencies of the 14-bp indel polymorphism of HLA-G were determined by direct counting. Binary logistic regression analysis was performed to calculate odds ratios (ORs) and 95% ...
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The Effect of Interferon Beta in HLA-G Expression on Monocyte in Diabetes Type1
... 2-Cunningham A,Carbone F, Geijtenbeek T. Langerhance cells and viral immunity.Eur. J. Immunol. 2008; 38:2377-2385. 3-Carosella ED, Moreau p, Le maoult J, Le Discorde M, Dausset J,Rouasferiss NHLA-G molecules: from ...
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HLA-G and HLA-E specific mRNAs connote opposite prognostic significance in renal cell carcinoma
... of HLA-G under neoplastic conditions is concerned, a body of literature has emerged supporting the immune-tolerogenic role of HLA-G based on worse prognosis of patients with HLA- ...
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HLA-G DNA sequence variants and risk of perinatal HIV-1 transmission
... the HLA-G sequence var- iants at nucleotide position C634G and 714insT/G observed between the mother and child of HIV-1-non- transmitting group may be in linkage disequilibrium with another variant ...
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Human Leukocyte Antigen-G (HLA-G) Expression in Cancers: Roles in Immune Evasion, Metastasis and Target for Therapy
... of HLA-G in tumor immune escaping, HLA-G was also found in association with the status of tumor invasion and metastasis in patients and preclin- ical models with the mechanism of upregulating ...
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Human Parthenogenetic Embryonic Stem Cell-Derived Neural Stem Cells Express HLA-G and Show Unique Resistance to NK Cell-Mediated Killing
... murine HLA-G ho- mologue and the lack of a suitable trans- plant model with a functional human im- mune system, in vivo testing of HLA-G function is difficult to perform and not always ...
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TGF-β induces HLA-G expression through inhibiting miR-152 in gastric cancer cells
... on HLA-G was thoroughly ...on HLA-G 3’UTR was analyzed through sequence analysis, with derived Mut-HLA-G 3’UTR ...h, HLA-G mRNA level showed significantly decrease ...
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“HLA-G 3′UTR gene polymorphisms and rheumatic heart disease: a familial study among South Indian population”
... Streptococcus; HLA-G: Human Leukocyte Antigen-G; HWE: Hardy- Weinberg equilibrium; IDC: Idiopathic dilated cardiomyopathy; JIA: Juvenile idiopathic arthritis; LD: Linkage disequilibrium; MVL: Mitral ...
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High plasma levels of HLA G are associated with low birth weight and with an increased risk of malaria in infancy
... barrier. HLA-G molecules are known to be expressed at the fetal–maternal interface on the surface of cytotrophoblast cells, endothelial cells and in amniotic fluid there by explaining the presence of ...
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Rescuing lymphocytes from HLA-G immunosuppressive effects mediated by the tumor microenvironment
... We first confirmed that our modified tumor cell lines expressed HLA-G and that our NK line expressed its receptor ILT2. We then showed that ILT2-shRNA significantly reduced ILT2 expression at the cell ...
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Fetal HLA-G alleles and their effect on miscarriage
... that the allele with the 3’ UTR 14bp deletion polymorphism was the most frequent allele in the study group (57%). The homozygous genotype of the same allele was about 2 times more common in the study group than in the ...
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Association of HLA-G 3′ UTR polymorphism and expression with the progression of cervical lesions in human papillomavirus 18 infections
... The HLA-G 14 bp Del and + 3142 C alleles seems to confer protection against, instead of being a risk factor for, HPV infections [10, 22, ...the HLA-G gene is associated with lower ...
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Evolution of the levels of human leukocyte antigen G (HLA G) in Beninese infant during the first year of life in a malaria endemic area: using latent class analysis
... The present analysis, confirms these results, and pro- vides new understanding by identifying new determi- nants of sHLA-G evolution. Indeed, although in the first study, the level of sHLA-G increased the ...
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Analysis of HLA-G Gene Expression in B-Lymphocytes from Chronic Lymphocytic Leukemia Patients
... of HLA-G in healthy controls is most probably due to lack of HLA-G gene expression and an approach with a large number of healthy controls using pure CD19 B- cells is warranted to clarify the ...
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The role of HLA-G in human pregnancy
... of HLA-G program uterine natural killer (NK) cells into pathways of tolerance [24-31] although this may also be a property of ...Soluble HLA-G proteins influence cytokine production by blood ...
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Modulation of HLA-G Expression in Human Neural Cells after Neurotropic Viral Infections
... 2-microglobulin-associated HLA-G forms (corresponding to the native HLA-G1 and HLA-G5 isoforms) (19, 39) was purchased from ...of HLA-G5 and HLA-G6 (HLA-G5/G6) (33) was ...
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Expression of Human Leukocyte Antigen G is associated with Prognosis in Nasopharyngeal Carcinoma
... examine HLA-G, CD68 and IL-10 expression in NPC tissue ...against HLA-G (1:200 dilution, sc-21799, Santa Cruz, USA), CD68 (1:100 dilution, ABIN370601, Dako, Denmark) and IL-10 (1:300 dilu- ...
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