HLA genes
HLA and non HLA genes in Behçet’s disease: a multicentric study in the Spanish population
... of HLA with BD remains ...the HLA region, three peaks of association with the disease were found: one of these single-nucleotide polymorphisms (SNPs) is located in the HLA-A region, another is ...
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Organic solvents and MS susceptibilityInteraction with MS risk HLA genes
... risk HLA genes and exposure to organic solvents regarding MS risk, similar to the previously reported gene-environment interaction involving the same MS risk HLA genes and smoke ...
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Non HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA defined subgroups of rheumatoid arthritis
... that HLA-DRB1*04, as well as other SE alleles, do not repre- sent a single determinant for development of autoimmune ...non-HLA genes could serve as possible second de- terminants for a break in ...
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Interplay between alcohol, smoking and HLA genes in RA aetiology
... of Hla-DrB1-Se interacted to increase the risk of acPa-positive ...among Hla-DrB1-Se positive subjects, there was also a significant interaction between non-drinking and smoking with regard to risk for ...
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Association between HLA genes and American cutaneous leishmaniasis in endemic regions of Southern Brazil
... study, HLA-B*45 was the only allele associated with a trend toward pro- tection from cutaneous ...Furthermore, HLA-B*45 involvement suggests that the common sequence for the antigen group may anchor ...
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Research of HLA II Class DRB1, DQA1, DQB1 Genetic Markers in Patients with HIV Infection and AIDS
... these genes were obtained in the researches with different HLA genes ...molecular genes of genetic polymorphism of HLA II class locus, on encoding process presentation antigen ...
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Diversity and Frequencies of HLA Class I and Class II Genes of an East African Population
... (HLA) genes are the most polymorphic genes within the human genome and play an important role in initiating the immune response to invading ...specific HLA alleles and increased/decreased risk ...
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HLAProfiler utilizes k-mer profiles to improve HLA calling accuracy for rare and common alleles in RNA-seq data
... the HLA genes replaced with specific HLA alleles unique to each ...subject. HLA allele se- quences were obtained from the IMGT/HLA database (v24) ...of HLA reads roughly matched ...
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The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients
... HLA genes encode numerous molecules including the HLA class I and II molecules, which have immunologi- cal ...with HLA-DRB1*1501 and nega- tively associated with HLA-DRB1*07 in ...
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HLA and migraine genes
... of HLA class I antigens in migraine was pub- lished by Lee Kudrow more than twenty years ago ...shared HLA haplo- types, suggesting that migraine heredity was HLA-linked ...if HLA genes ...
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Associations between the HLA Apolymorphism and the clinical manifestations of Behcet's disease
... Continuous values are presented as means ± standard deviations. The chi-square test or Fisher ’ s exact test was used to compare the phenotypic frequencies of HLA-A alleles between patients and controls or between ...
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Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis
... – HLA MS risk gene interaction, we primarily consider a low-grade chronic inflammation with activation of the innate immune system, promoted by the fat tissue, 4 which may increase ...
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Expression of HLA-DR genes in gliomas: correlation with clinicopathological features and prognosis
... was performed to define the new variable, which can rep- resent the expression characteristics of the entire HLA- DR gene group. Patients with different tumor grades were classified into two subgroups for further ...
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HLA polymorphisms and detection of kaposi sarcoma-associated herpesvirus DNA in saliva and peripheral blood among children and their mothers in the uganda sickle cell anemia KSHV Study
... high-resolution HLA-A, -B and -DRB1 typing on residual DNA obtained from saliva or buffy coat of the children and their mothers from the KSHV viral ...S3/S4 HLA SINGLE ALLELE SEQUENCING SET, PROTRANS ...
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Comprehensive Analysis of HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 Loci and Squamous Cell Cervical Cancer Risk
... of HLA molecules on the pathogenesis of HPV-related anogenital cancer more generally, we examined the association of these alleles with cervical adenocarcinoma(14) and vulvar carcinoma(15) using cases from our ...
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Analysis of HLA D micropolymorphism by a simple procedure: RNA oligonucleotide hybridization
... optimal HLA typing for transplantation and for a reevaluation of HLA-disease ...the HLA loci, including new alleles, not identified with previous ...optimize HLA matching, in particular for ...
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Pregnancy immunogenetics: NK cell education in the womb?
... frequency of the C2 epitope to those who have a high frequency of B haplotypes and a high frequency of C2. This heavy foot- print, which acts universally to reduce the frequency of KIR AA mothers carrying C2 babies, is ...
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Specific HLA-DRB and -DQB Alleles and Haplotypes Confer Disease Susceptibility or Resistance in Bahraini Type 1 Diabetes Patients
... Type 1 diabetes is an autoimmune disease characterized by insulin insufficiency resulting from a progressive immunologic destruction of insulin-secreting pancreatic  islet cells by au- toreactive leukocytes and their ...
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Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases
... of HLA-A was as- sociated with larger tumors in both SCC and AC, which is consistent with a study in breast cancer reporting that lar- ger tumors manifest with low HLA class I expression ...non-classical ...
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In Silico Analysis of Single Nucleotide Polymorphisms (SNPs) in Human HLA-A and HLA-B Genes Responsible for Renal Transplantation Rejection
... The human leukocyte antigen (HLA) system is the name of the major histocompatibility complex (MHC) in humans, which generally inherited from parents as a one set name haplotype, furthermore human leukocyte antigen ...
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