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HNSCC patients

Pretreatment oral hygiene habits and survival of head and neck squamous cell carcinoma (HNSCC) patients

Pretreatment oral hygiene habits and survival of head and neck squamous cell carcinoma (HNSCC) patients

... Interview-based assessment of oral hygiene habits and other health behavior variables was performed during hospitalization of HNSCC patients. The median time point of the Interview was 6 days after primary ...

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HPV-16 infection modifies overall survival of Puerto Rican HNSCC patients

HPV-16 infection modifies overall survival of Puerto Rican HNSCC patients

... of HNSCC patients, and evidence has accumulated showing that HPV is etiologic for OPSCC [18, ...positive HNSCC patients have a distinct cancer progres- sion and prognosis than HPV-16 negative ...

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Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression

Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression

... in HNSCC patients carrying TP53 mutations when compared to those bearing wt-p53 ...cancer patients reveals that low expression of DNA repair genes correlates significantly with reduced relapse free ...

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Identification and validation a TGF β associated long non coding RNA of head and neck squamous cell carcinoma by bioinformatics method

Identification and validation a TGF β associated long non coding RNA of head and neck squamous cell carcinoma by bioinformatics method

... of HNSCC were revealed in our ...in HNSCC and association with worse patient ...the HNSCC patients with low and high TGFβ levels (p < ...analysis, patients with high TGFβ expression ...

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Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas

... Five morphologically representative areas were selected from each individual paraffin-embedded tumor block: two for DNA isolation and three for the construction of a tissue microarray (TMA). To avoid cross-contamination, ...

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Effect of sorafenib on cisplatin-based chemoradiation in head and neck cancer cells

Effect of sorafenib on cisplatin-based chemoradiation in head and neck cancer cells

... HNSCC patients treated with CRT versus RT alone [2, ...four HNSCC cell ...for patients receiving the targeted agent in addition to CRT [5, 20, ...

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Dynamic cellular and molecular modulations of diabetes mediated head and neck carcinogenesis

Dynamic cellular and molecular modulations of diabetes mediated head and neck carcinogenesis

... for HNSCC development, the impact of metabolic imbalance was less emphasized during HNSCC ...in HNSCC patients; however, the outcomes from different groups are contradictive and underlying ...

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Identification of Head and Neck Cancer Subtypes Based on Human Papillomavirus Presence and E2F-Regulated Gene Expression

Identification of Head and Neck Cancer Subtypes Based on Human Papillomavirus Presence and E2F-Regulated Gene Expression

... 499 HNSCC patients was compared to the median of its expression in normal tissue and categorized accordingly: upregulated if the tumor expression value for that gene is greater than the gene’s normal median ...

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Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus

Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus

... in patients with HNSCC was observed. One of 9 HNSCC patients discontinued therapy after the first cetuximab infusion due to grade 3 infusion ...evaluable patients, seven patients ...

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Clinical Evaluation of Sialic Acid In Head and Neck Squamous Cell Carcinoma Patients and Tobacco Chewers or Smokers with No Cancer

Clinical Evaluation of Sialic Acid In Head and Neck Squamous Cell Carcinoma Patients and Tobacco Chewers or Smokers with No Cancer

... activity. Patients with cancer have been reported to have significant elevations of serum Total Sialic Acid (TSA) and Lipid Bound Sialic Acid (LBSA) levels as compared to control ...diagnosed HNSCC ...

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Original Article Reduced serum miR-138 is associated with poor prognosis of head and neck squamous cell carcinoma

Original Article Reduced serum miR-138 is associated with poor prognosis of head and neck squamous cell carcinoma

... 113 HNSCC cases and 60 ...in HNSCC patients compared to healthy ...32 patients after receiving surgical treatment were significantly ...discriminate HNSCC patients from controls ...

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Original Article MiR-31 is a potential biomarker for diagnosis of head and neck squamous cell carcinoma

Original Article MiR-31 is a potential biomarker for diagnosis of head and neck squamous cell carcinoma

... 118 patients with HNSCC and 48 patients with oral epithelial dysplasia, and blood samples were collected from all the HNSCC cases and 60 normal ...for HNSCC. Our findings showed that ...

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Prognostic Score Predicts Survival in HPV-Negative Head and Neck Squamous Cell Cancer Patients

Prognostic Score Predicts Survival in HPV-Negative Head and Neck Squamous Cell Cancer Patients

... of HNSCC and identified a higher mutational load and TP53 mutation, not other driver mutations in smokers compared to non- smokers ...wild-type HNSCC patients ...of HNSCC and reported lower ...

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CD73 is associated with poor prognosis in HNSCC

CD73 is associated with poor prognosis in HNSCC

... human HNSCC, we performed immunohistochemical staining of CD73 in human HNSCC tissue including normal oral mucosa (n = 51), epithelial dysplasia (n = 11) and HNSCC (n = ...of HNSCC cells ...

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MAGE-A11 Expression Predicts Patient Prognosis in Head and Neck Squamous Cell Carcinoma

<p>MAGE-A11 Expression Predicts Patient Prognosis in Head and Neck Squamous Cell Carcinoma</p>

... Two independent pathologists were separated to deal with the evaluation for positive DAB staining of all the immu- noreactions. Exam every slide fi ve times, and observed 100 cells during each examination using a medical ...

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Targeting EZH2 regulates tumor growth and apoptosis through modulating mitochondria dependent cell-death pathway in HNSCC

Targeting EZH2 regulates tumor growth and apoptosis through modulating mitochondria dependent cell-death pathway in HNSCC

... of HNSCC tissues and contributed to tumor differentiation status [26, ...of HNSCC patients. And examination of HNSCC specimens showed EZH2 expression was associated with tumor size, ...

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Circulating small non coding RNA signature in head and neck squamous cell carcinoma

Circulating small non coding RNA signature in head and neck squamous cell carcinoma

... in HNSCC patients has not significantly changed for the last ...in HNSCC carcinogenesis could allow an earlier diagnosis and the use of more specific and effective ...from HNSCC ...

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TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

... in HNSCC using the publicly available TCGA ...in HNSCC samples as compared to their non-tumor counterparts, while TEAD1 and TEAD3 were markedly downregulated in cancerous samples relative to non- tumor ...

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Impact of Pre Radiotherapy and/or Chemoradiotherapy Hemoglobin Level on Response to Treatment in Laryngeal and Hypophayrngeal Squamous Cell Carcinoma

Impact of Pre Radiotherapy and/or Chemoradiotherapy Hemoglobin Level on Response to Treatment in Laryngeal and Hypophayrngeal Squamous Cell Carcinoma

... 91 patients with HNSCC for the effect of pre-RT Hb levels in locally advanced HNSCC treated with CCRT, the authors found that performance status, pre-RT hemoglobin lev- el, radiotherapy interruptions ...

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CT Perfusion Can Predict Overexpression of CXCL8 (Interleukin 8) in Head and Neck Squamous Cell Carcinoma

CT Perfusion Can Predict Overexpression of CXCL8 (Interleukin 8) in Head and Neck Squamous Cell Carcinoma

... Pearson correlation showed a statistically significant positive correlation between CXCL8 expression level and rBF (r ⫽ 0.94, P ⫽ .01; Fig 4). Spearman rank correlation coefficient also showed positive correlation ...

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