HO-1 and HO-2
Hemeoxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy
... Here we report that the expression of both HO-1 (inducible) and HO-2 (constitutive) were. Reverse transcription-PCR analysis re- vealed that mRNA encoding HO-1 and HO-2 was unde- tected [r] ...
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Hemeoxygenase 1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy
... both HO-1 (inducible) and HO-2 (constitutive) were ...the HO-CO pathway by the HO inducer, hemin (10 m M), completely inhibited spontaneous contractility ( n 5 ...under 2 ...
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Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase 1 deficiency
... isoforms, HO- 1 and ...place. HO-2 is constitutively produced within the brain and testes, whereas HO-1 is produced ubiquitously, but only marginally in the resting state ...of ...
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Induction of Placental Heme Oxygenase-1 Is Protective Against TNFα-induced Cytotoxicity and Promotes Vessel Relaxation
... of HO-1 to the perivascular contractile sheath of developing vessels and media of large stem vessels may indicate its importance for regulating feto- placental ...of HO-2 suggests that it acts ...
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Heme oxygenase 1 deficiency accompanies neuropathogenesis of HIV associated neurocognitive disorders
... and HO-2) are expressed to varying levels in nearly all cell lineages, but only HO-1, the rapidly inducible isoform, is considered to be a criti- cal mediator of the cellular response to ...
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Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase 2
... the HO-1 gene contains several AP-1 binding sites that show regulation in oxidative stress ...Since HO-1 is readily inducible in oxidant stress, and the reactions of HO lead to ...
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Heme oxygenase 1 gene induction as an intrinsic regulation against delayed cerebral vasospasm in rats
... antisense HO-1 ODN treatment on delayed ...of HO-1 gene induction in the basilar artery and brain, we examined the effects of selective HO-1 inhibition using antisense ...
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Possible contribution of endogenous carbon monoxide to the development of allergic rhinitis in guinea pigs
... organs. HO consists of three isozymes: HO-1, HO-2 and ...HO-3. HO-1, which is known as inducible form of heat shock protein 32 (HSP32), has been implicated in the ...
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Induction of heme oxygenase-1 protects against nutritional fibrosing steatohepatitis in mice
... of HO have been characterized: the stress-inducible protein HO-1, widely expressed at a low level in mammalian tissues and can be induced by a variety of stimuli, including heme, heavy metals, cyto- ...
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EFFECTIVENESS OF STORY TELLING APPROACH IN INCULCATING VALUES IDENTIFID BY NCERT AMONGTHE 6th GRADE LEARNERS OF ODISHA STATE
... HYPOTHESES OF THE STUDY: Ho 1 Storytelling approach has significant effect on development of values among 6th grade learners than traditional method with reference to gender Ho 2 Student[r] ...
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Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase 1 null mice
... inducible HO isoform (HO-1) but not the constitutive isoform ...whether HO-1 affects cellular adaptation to chronic hypoxia in vivo, we generated HO-1 null ...
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Differential and Combined Effects of Simvastatin and Vildagliptin on Angiogenic Markers and Oxidative Stress in Hind Limb Model of Ischemia in Diabetic Rats
... After animal scarification blood samples were collected on EDTA and centrifuged at 1000xg for 15 min, plasma samples were separated and stored at 4ºC for the determination of VEGF and HO-1. Gastrocnemius ...
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Mitochondrial quality-control dysregulation in conditional HO-1–/– mice
... that HO-1–dependent induc- tion of NRF-1 enhances mitochondrial quality control (QC) pathway function, allowing the beating rate of the cells to improve, while the silencing of HO-1 and ...
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Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice
... that HO-1 mediated protection was accompanied by significantly reduced cas- pase-3 activation ...[38]. HO-1 regulated mitochondrial transport carriers and function by activating Bcl-2 ...
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Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway
... Melatonin (N-acetyl 5-methoxytryptamine) and its meta- bolites have been shown to enforce the antioxidant system by scavenging free radicals [21,46]. Melatonin stimulates synthesis of antioxidant enzymes [47] and ...
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Isoflurane Preconditioning at Clinically Relevant Doses Induce Protective Effects of Heme Oxygenase-1 on Hepatic Ischemia Reperfusion in Rats
... containing 1% Triton X-100, 0.5% NP-40, 1 mM EGTA, 1 mM EDTA, 150 mM NaCl and 1 mM ...the HO-1 (dilution 1:2000; ABCAM; Cambridge, UK) for 2 ...of 1:2000 for ...
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Heterotopic ossifications after arthroscopic management of femoroacetabular impingement: the role of NSAID prophylaxis
... about HO only if the lesion is bulky (grade 3 or 4), but hip arthroscopy patients are generally younger, more active, and motivated to return to sport activities, even at competitive ...
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The Uptake of HO₂ on Meteoric Smoke Analogues
... The publisher or other rights-holder may allow further reproduction and re-use of this version - refer to the White Rose Research Online record for this item.. Where records identify the[r] ...
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Upregulation of heme oxygenase-1 expression by curcumin conferring protection from hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblasts
... Oxidative stress-induced apoptosis has long been impli- cated in the pathogenesis of cardiovascular diseases such as myocardial ischemic injury and infarction [1, 2]. Oxidative damage, mediated by reactive ...
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Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells
... Dulbecco ’ s modified Eagle ’ s medium (DMEM) and fetal bovine serum (FBS) were purchased from Invitrogen (Carlsbad, CA, USA). Polyclonal antibodies HO-1, TLR4, and MyD88 were purchased from Santa Cruz ...
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