HO-1 oxidative stress
Effects of ulinastatin combined with hemoperfusion on renal function, fibrosis indexes and oxidative stress indexes of patients with paraquat poisoning
... of oxidative stress is the pathological link closely related to both renal damage and pulmonary fibrosis in the process of paraquat poisoning, and the mass generation of oxygen free radicals is the ...
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Baicalin mitigated Mycoplasma gallisepticum-induced structural damage and attenuated oxidative stress and apoptosis in chicken thymus through the Nrf2/HO-1 defence pathway
... increased oxidative stress induced immune impairment through cellular DNA damage and bio- molecule fragmentation ...produces oxidative stress, which further exacerbates the inflammatory ...
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Original Article Overexpression of miR-153 promotes oxidative stress in MPP -induced PD model by negatively regulating the Nrf2/HO-1 signaling pathway
... that oxidative stress might be a dominant mecha- nism contributing to neuronal degeneration [9, ...to oxidative stress, binds to antioxidant response element (ARE) in the nucleus and promotes ...
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Hesperidin protects against diethylnitrosamine/carbon tetrachloride-induced renal repercussions via up-regulation of Nrf2/HO-1 signaling and attenuation of oxidative stress
... protein 1 (Keap1) through the DC domain of either one of the Keap1 ...of oxidative/electrophilic or xenobiotic stress, the Cullin3/Rbx1-dependent polyubiquitination of Nrf2, resulting in the ...
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Methyl lucidone exhibits neuroprotective effects on glutamate-induced oxidative stress in HT-22 cells via Nrf-2/HO-1 signaling
... of HO-1, we also measured the protein levels of Nrf-2 from the nuclear fraction of the HT-22 ...of HO-1 by regulating Nrf-2 ...of HO-1 involvement in the MLC effects, SnPP, an ...
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<p>Methyl Jasmonate Protects Microglial Cells Against β-Amyloid-Induced Oxidative Stress and Inflammation via Nrf2-Dependent HO-1 Pathway</p>
... oxidant stress and in fl ammation by regulating several molecular signaling pathways such as Nrf2/HO-1, NF- κ B, and ...and HO-1 to maintain the intracellular redox ...Nrf2/ ...
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Melatonin protects against burn induced hepatic oxidative injury by inducing HO 1 via the Nrf2 pathway
... against oxidative injury and gives rise to a cascade of metabolites (AFMK and AMK) that share its an- tioxidant and anti-inflammatory properties (Reiter et ...elevated oxidative stress (Rodriguez et ...
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Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 and inhibition of the NF-κB pathways
... Abundant evidence has been gathered showing ALT plays important roles in the NF-κB/COX-2-mediated signaling cascades and IKKβ kinase activity [34]. The nu- clear factor-κB (NF-κB) pathway has been shown to play critical ...
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Original Article Bilobalide ameliorates carbon tetrachloride-induced oxidative damage in HepG2 cells by the induction of Nrf2-dependent HO-1 expression through PI3K/Akt and P38 pathways
... Herbal productions have been long used to treat liver disease. These agents exhibit hepa- toprotective effects via various mechanisms such as inhibiting oxidative stress, inflammato- ry response, ...
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Neuroprotective effects of an Nrf2 agonist on high glucose-induced damage in HT22 cells
... to oxidative stress, triggers the production of various antioxidant enzymes and phase II detoxification enzymes, including haem oxygenase-1 (HO-1), quinone oxidoreductases (NQO1) and ...
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Original Article Lycopene attenuates LPS-induced liver injury by inactivation of NF-κB/COX-2 signaling
... [53]. HO-1, an antioxidant enzyme, can decompose heme into biliverdin, carbon mon- oxide (CO), and free ...of HO-1 such as biliverdin and CO have been dem- onstrated to possess antioxidation ...
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Ifnγ Selectively induces Astrocyte Heme Oxygenase-1 Degradation: A Novel Proteasome Role in HIV Neuropathogenesis
... drives HO-1 protein dloss in HIV-infected brain and suggests that persistently elevated IFNγ is a critical modulator linking chronic immune activation to ...of HO-1 expression, which would be ...
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Original Article Sulforaphane attenuates acute lung injury by inhibiting oxidative stress via Nrf2/HO-1 pathway in a rat sepsis model
... Pulmonary oxidative stress was significantly increased (reduced SOD activity, enhanced 8-OHdG concentration, elevated 15-F2t-isoprostane level, and enhanced 4-HNE expression) in sepsis that were associated ...
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“Ginger Extract Attenuates Ethanol - Induced Oxidative Stress in Rat Small Intestine” by Jeepalem. Himabindu, Ganjikunta. Venkata Subbaiah, Sahukari. Ravi, Basha.Shanmugam, Kesireddy. Sathyavelu Reddy, India.
... The oxidative stress caused by reactive oxygen species (ROS) produced during extensive ethanol metabolism is suggested as one of the main important mechanisms underlying the toxicity 3 ...
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Original Article Significance of detecting oxidative stress and inflammatory response in the treatment of vascular crisis after finger replantation
... traumatic stress, mainly including IL-6 and TNF-α, the former mediated the inflammatory response, while the latter induced the inflammatory response [18, ...
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OXIDATIVE STRESS AND DIABETES: AN OVERVIEW
... Diabetes is also caused by the false immune response of the body, i.e. response against self-cells and self-biomolecules. Immune response of the body is directly linked with all the three types of diabetes where β - ...
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Mitochondrial Deficiencies and Oxidative Stress in Parkinson's Disease: A Slippery Slope to Cell Death
... Sporadic mutations in α -synuclein constitute 95% of PD cases. The other 5% of occurrences are attributed to a mixture of dominant and recessive genes. Dominant forms of PD have familial mutations in α -synuclein which ...
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Plasma protein carbonyl responses to anaerobic exercise in female cyclists
... aerobically-trained, and anaerobically- trained athletes following anaerobic exercise. In addition, the mode of training that an athlete engages in may influence PC levels following exercise. In this regard, it has ...
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<em>Astragalus </em>polysaccharides inhibit oxidation in high glucose-challenged or SOD2-silenced H9C2 cells
... detect oxidative damage to cytoplasmic proteins and oxidative stress in the nuclei, ...reduced oxidative damage to cytoplasmic proteins (nitrotyrosine) and oxidative stress in ...
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Oxidative stress, cell cycle, and neurodegeneration
... of oxidative stress and abnor- mal cell cycle checkpoint function and reports of aber- rant neuronal cell cycle reentry in progressive human neurodegenerative diseases, we investigated whether neu- rons in ...
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