HO, heme oxygenase
Relationship of Heme Oxygenase-1 (HO-1) Level with Onset and Severity in Normotensive Pregnancy and Severe Preeclampsia
... of heme oxygenase-1 (HO-1) is at ...of heme-oxygenase-1 (HO-1) level is ...of heme oxygenase-1 (HO-1) level showed that p value: ...of heme ...
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Stimulation of heme oxygenase in macrophages and liver by endotoxin
... stimulated heme oxygenase (HO) activity, which was additive to the substrate-mediated enzyme induction produced by the ingested erythrocyte ...rats, HO activity in both parenchymal and ...
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DMO CAP inhibits influenza virus replication by activating heme oxygenase 1 mediated IFN response
... of HO-1 HO-1 expression is up-regulated not only by its substrate, heme, but also by various non-heme inducers, such as heat shock, inflammatory cytokines, endotoxin, and oxida- tive stress ...
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Heme oxygenase-1 gene promoter polymorphisms are associated with coronary heart disease and restenosis after percutaneous coronary intervention: a meta-analysis
... that HO-1 gene polymorphisms were associated with CHD ...the HO-1(GT)n locus may promote HO-1 gene expression and result in increased protein production, thereby raising bilirubin levels and so ...
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Original Article Transplantation induced pluripotent stem cells in situ improves fertility outcome impaired by intrauterine adhesions in mice
... of heme-oxygenase-1 (HO-1) gene in exerting such ...down HO-1 expression, the effect of iPSCs was significantly ...and HO-1 gene play an important role in regulating the therapeutic ...
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Original Article Heme oxygenase-1 mediates the protective effect of Rosa Laevigata Michx on doxorubicin induced myocardial cell injury
... whether heme oxygenase-1 (HO-1) is involved in the protective ef- fect of Rosa Laevigata Michx (RLM) on myocardial cell injury induced by doxorubicin ...a HO-1 inhibitor) ...(LDH), HO-1 ...
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Neuroinflammatory signals enhance the immunomodulatory and neuroprotective properties of multipotent adult progenitor cells
... peroxide, HGF, Hepatocyte growth factor; hMAPC: Human multipotent adult progenitor cells; HMBS: Hydroxymethylbilane synthase; HO-1: Heme oxygenase 1; Ido-1: iIndoleamine 2,3-dioxygenase [r] ...
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The effect of methyl sulphonyl methane supplementation on biomarkers of oxidative stress in sport horses following jumping exercise
... is heme metabolism by heme-oxygenase (HO) ...This HO-CO pathway has been recently proposed to be involved in the defence against oxidative stress and the deleterious effects of NO, ...
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<em>Paeonia lactiflora</em> Pall. protects against ANIT-induced cholestasis by activating Nrf2 via PI3K/Akt signaling pathway
... Materials and methods: Liquid chromatography-mass spectrometry (LC-MS) was performed to identify the main compounds present in PLP. The mechanism of action of PLP and its thera- peutic effect on cholestasis, induced by ...
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GWAS identified CCR1 and IL10 loci contribute to M1 macrophage predominant inflammation in Behçet’s disease
... of heme oxygenase (HO)-1, which is preferentially expressed as an M2 Mφ-specific anti-inflammatory protein, suggested M2 Mφ dysfunction in BD ...
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Heme oxygenase and carbon monoxide protect from muscle dystrophy
... We have leveraged here the transcriptional coactivator PGC-1α to identify a novel pathway, involving the heme oxygenase enzyme and its enzymatic product carbon monoxide, as potent protective agents against ...
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Far-infrared therapy for secondary vascular access patency of hemodialysis patients
... Vascular access (VA) is necessary for patients on main- tenance hemodialysis (HD). The prognosis of VA in HD patients is presumably influenced by the following fac- tors: enhanced coagulation properties, injury to ...
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Original Article Xylaria nigripes protects mice against cerebral ischemic injury by activating Nrf2/HO-1 pathway
... (Nrf2), heme oxygenase-1 (HO-1), GFAP, NGFR, BDNF, NTRK1, and NTRK2 expression were assessed in the ischemic mouse ...by HO-1 inhibitor ...of HO-1, Nrf2, and markers of neurons and ...
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Inhibitory effect of phytol on cellular senescence
... 2), HO-1 (heme oxygenase 1), 14-3-3σ (Stratifin), cyclin B mRNA, and CASP3 was performed to examine the cytoprotective effects of phytol, as evidenced by increased mRNA expression of the ...
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Heme oxygenase 1 deficiency accompanies neuropathogenesis of HIV associated neurocognitive disorders
... for HO-1 in modulating macro- phage glutamate production and neurotoxicity, we used tin(IV) mesoporphyrin IX dichloride (SnMP), a potent inhibitor of HO-1 and HO-2 enzymatic activity (44), which also ...
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Induction of Placental Heme Oxygenase-1 Is Protective Against TNFα-induced Cytotoxicity and Promotes Vessel Relaxation
... of HO activa- tion is bilirubin that is a lipid-soluble metabolite of the ...placental HO-1 activation in preeclamp- tic placenta. In a human case of HO-1 deficiency, there is severe, persistent ...
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Pharmacological Inhibition of Host Heme Oxygenase 1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes
... We next evaluated whether adjunctive administration of SnPPIX could enhance the efficacy of conventional anti-TB drug therapy. To do so, we treated infected mice at 4 weeks postinfec- tion with either rifampin (R), ...
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Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling
... Although concern remains about the athero-thrombotic risk posed by cyclo-oxygenase (COX)-2- selective inhibitors, recent data implicates rofecoxib, while celecoxib appears equivalent to NSAIDs naproxen and ...
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The active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase 1
... of heme oxygenase 1 (Hmox1) was performed using TaqMan gene expression assays (Table 1) (Applied Bio- systems, Foster City, CA, USA) on a lightcycler 480 PCR system (Roche, Mannheim, ...against HO-1 ...
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<p>HO-1 concentrations 24 hours after cardiac surgery are associated with the incidence of acute kidney injury: a prospective cohort study</p>
... of HO-1 suggests that renal stress leading to AKI might be caused by, eg, inappropriate fluid management, diuretic treatment, appearance of cardiac shock or cardiac ...
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