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Hormone Sensitive Lipase (HSL)

Hormone-Sensitive Lipase Knockouts

Hormone-Sensitive Lipase Knockouts

... be hormone-sensitive lipase (HSL). Studies of HSL knockouts have provided important insights into the functional significance of HSL and into adipose metabolism in ...that ...

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Extract of Paecilomyces hepiali mycelia induces lipolysis through PKA mediated phosphorylation of hormone sensitive lipase and ERK mediated downregulation of perilipin in 3T3 L1 adipocytes

Extract of Paecilomyces hepiali mycelia induces lipolysis through PKA mediated phosphorylation of hormone sensitive lipase and ERK mediated downregulation of perilipin in 3T3 L1 adipocytes

... triglyceride lipase (ATGL) and perilipin, as well as phosphorylation of hormone-sensitive lipase (HSL), AMP-activated protein kinase (AMPK), and mitogen-activated protein kinases ...

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Overexpression of hormone sensitive lipase prevents triglyceride accumulation in adipocytes

Overexpression of hormone sensitive lipase prevents triglyceride accumulation in adipocytes

... Hormone-sensitive lipase (HSL) is a cytosolic neutral lipase that hydrolyzes intracellular stores of triglycerides within adipocytes and is thought to be the rate limiting enzyme in ...

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The substrate specificity of hormone sensitive lipase from adipose tissue
of the Antarctic fish Trematomus newnesi

The substrate specificity of hormone sensitive lipase from adipose tissue of the Antarctic fish Trematomus newnesi

... Antarctic fishes of the suborder Notothenioidei characteristically possess large stores of neutral lipids that have been shown to be important both in conferring buoyant lift and as a caloric resource for energy ...

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The Mechanism of Activation of Hormone Sensitive Lipase in Human Adipose Tissue

The Mechanism of Activation of Hormone Sensitive Lipase in Human Adipose Tissue

... nonactivated hormone-sensitive lipase to its activated form, as indicated by a decrease in the activation subsequently obtainable in fractions prepared from such hormone-treated ...of ...

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Depot-specific differences in perilipin and hormone-sensitive lipase expression in lean and obese

Depot-specific differences in perilipin and hormone-sensitive lipase expression in lean and obese

... The present study reported regional differences in lipoly- sis regulation. Basal lipolysis and maximal noradrenaline- stimulated lipolysis expressed per cell number increased in SC versus OM adipocytes in the obese ...

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The regulation of hormone-sensitive lipase in macrophages

The regulation of hormone-sensitive lipase in macrophages

... the lipase w ith its su b strate a n d associated in tracellu lar m em ...triglyceride lipase activity is observed u p o n lipolytic stim ulation in adipocytes (Egan et ...transports HSL to the ...

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Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus

Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus

... As observed by Hoptamisligil [12], among the most crit- ical processes to species survival are the ability to with- stand starvation and the capacity to mount an effective immune response to pathogens. The former selects ...

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Lipolytic Effect of Eumicrotremus orbis Water Extracts in Differentiated 3T3-L1 Adipocytes

Lipolytic Effect of Eumicrotremus orbis Water Extracts in Differentiated 3T3-L1 Adipocytes

... EOWE, hormone sensitive lipase (HSL) and phosphorylated HSL (p-HSL) protein level increased by approximately ...triglyceride lipase (ATGL) protein level did not effect as ...

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Effects of liraglutide on lipolysis and the AC3/PKA/HSL pathway

<p>Effects of liraglutide on lipolysis and the AC3/PKA/HSL pathway</p>

... glycerin. Hormone-sensitive lipase (HSL) in adipose tissue has been suggested to be a key regulatory enzym in controlling ...phosphorylates hormone-sensitive lipase ...

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Production and Purification of a New Inhibitor of Pancreatic Lipase andHormone Sensitive Lipase from Soil Actinomycetes

Production and Purification of a New Inhibitor of Pancreatic Lipase andHormone Sensitive Lipase from Soil Actinomycetes

... The lipase inhibitory activity was assessed using different lipases: Pancreatic lipase (PL),Hormone sensitive lipase(HSL)[13],Monoacylglycerol ...microbial lipase ...

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Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia

Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia

... in hormone-sensitive lipase activity in the whole material, and with the serum values for triglycerides, HDL cholesterol and apoB lipoprotein within the control group, but ...

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Physiogenomic analysis of weight loss induced by dietary carbohydrate restriction

Physiogenomic analysis of weight loss induced by dietary carbohydrate restriction

... six lipase genes listed in order of genetic association significance, as follows: LIPF gastric lipase, LIPC hepatic lipase, LIPG endothelial lipase, LIPE hormone-sensitive ...

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Effects of dietary dihydropyridine supplementation on growth performance and lipid metabolism of broiler chickens

Effects of dietary dihydropyridine supplementation on growth performance and lipid metabolism of broiler chickens

... the hormone- sensitive triglyceride lipase activity in liver and abdominal fat (P < ...lipoprotein lipase activity in abdominal fat was significantly decreased by dihydropyridine (P < ...

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A heartfelt response: new thyroid hormone–sensitive neurons in the hypothalamus

A heartfelt response: new thyroid hormone–sensitive neurons in the hypothalamus

... thyroid hormone regulates such a wide range of cellular pro- cesses in so many different ...same hormone stimulate the dif- ferentiation of an embryonic neuroblast but trigger an entirely different response ...

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Production of phenylacetyl-homoserine lactone analogs by artificial biosynthetic pathway in Escherichia coli

Production of phenylacetyl-homoserine lactone analogs by artificial biosynthetic pathway in Escherichia coli

... Using the same experimental conditions described above, the tyrosine-overproducing E. coli ΔCOS1 strain harboring the pET-opT4R vector (DN2) produced more than 60.9 ± 0.5 mg/L of p-coumaroyl-HSL, an increase of ...

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Impact of quorum sensing on cell aggregation in enteropathogenic and enterohaemorrhagic Escherichia coli : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosphy in Microbiology and Genetics at Massey University

Impact of quorum sensing on cell aggregation in enteropathogenic and enterohaemorrhagic Escherichia coli : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosphy in Microbiology and Genetics at Massey University, Turitea campus, New Zealand

... Variation in the diameter of the motility zones produced by AE2348/69 luxS- in the presence and absence of different AHLs at 25°C.. hexanoyl-D-HSL and N-3-oxododecanoyl-D-HSL at 25°C Fig[r] ...

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Treatment of Oligometastatic Hormone Sensitive Prostate Cancer: A Comprehensive Review

Treatment of Oligometastatic Hormone Sensitive Prostate Cancer: A Comprehensive Review

... Even minimal disease, such as a single positive pelvic lymph node LN, precluded a definitive therapy, and these patients were treated with androgen-deprivation therapy ADT.8 However, wit[r] ...

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Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway

Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway

... The effects of BBR on HSL and ATGL were similar to those of thyrotropin (TSH). TSH has been found to ex- hibit bidirectional effects on lipolysis. Studies have found that TSH stimulated the expression of ...

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The role of hormone therapy and chemotherapy in oligometastatic prostate cancer

The role of hormone therapy and chemotherapy in oligometastatic prostate cancer

... Oligometastatic disease was proposed by Hellman and Weichselbaum in 1995 as an intermediate tumour state between localised lesions and widespread metastases, characterised by the limited number and size of metastases in ...

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