HSV, Herpes Simplex Virus
Amplification of Reiterated Sequences of Herpes Simplex Virus Type 1 (HSV 1) Genome To Discriminate between Clinical HSV 1 Isolates
... Herpes simplex virus type 1 (HSV-1)-related disease ranges from a localized, self-limiting illness to fatal disease in immunocompromised ...latent virus or reinfection with an exogenous ...
6
Herpes simplex virus 2 (HSV 2) type specific antibody correlates of protection in infants exposed to HSV 2 at birth
... recurrent HSV-2. Antibodies to HSV-2 proteins gG-2, VP5, and ICP35 were detected in 83, 89, and 72% of the 36 uninfected infants, ...of HSV-2 were then analyzed separately; these profiles were ...
5
Implication of human herpesviruses in oncogenesis through immune evasion and supression
... HSV: Herpes simplex virus; VZV: Varicella zoster virus; EBV: Epstein-barr virus; HCMV: Human cytomegalovirus; KSHV: Kaposi sarcoma-associated herpes virus; CNS: ...
8
Expression of Herpes Simplex Virus 1-Encoded MicroRNAs in Human Trigeminal Ganglia and Their Relation to Local T-Cell Infiltrates
... Herpes simplex type 1 (HSV-1) is a neurotropic virus which establishes lifelong latency in human trigeminal ganglia ...of HSV-1 latency are discussed: antiviral CD8 ⴙ T cells and viral ...
6
Functional Analysis of the Triplex Proteins (VP19C and VP23) of Herpes Simplex Virus Type 1
... the HSV-1 scaffold C-terminal 25 amino ...etch virus cleavage site between the histidine handle and the foreign protein allows for subsequent removal of the histidine ...the HSV-1 capsid ORFs for ...
12
Role of Herpes Simplex Virus 1 γ34.5 in the Regulation of IRF3 Signaling
... HSV-1 ICP34.5 binds overexpressed but not endogenous TBK1. Amino acids 72 to 106 of HSV-1 ICP34.5 have been previously reported to bind ICP34.5 to the host antiviral factor TBK1 (18). In order to evaluate ...
13
The Natural History of Herpes Simplex Virus Infection of Mother and Newborn
... Neonatal Herpes Simplex Virus Study: Maternal Herpetic Infection.. 5 Neonatal HSV Infection.[r] ...
8
Establishment of a novel therapeutic vector targeting the trigeminal ganglion in rats
... of herpes simplex keratitis, herpes simplex virus type 1 (HSV-1) infection begins in corneal epithelium cells and then progresses through the sensory nerve endings and finally ...
8
Mapping autoantigen epitopes: molecular insights into autoantibody-associated disorders of the nervous system
... following herpes simplex virus encephalitis ...between HSV and development of autoimmune disorders, whether or not molecular mimicry is involved is still ...pes simplex virus ...
23
Sexually transmitted infections among patients with herpes simplex virus at King Abdulaziz University Hospital
... between HSV-2 seroprevalence and HIV infec- tion [8-10]. HSV-2 positive patients were found to have an increased risk of acquiring HIV infection, which has been explained by the disruption of the genital ...
5
GENITAL HERPES DISEASES: AN OVERVIEW
... Genital herpes is an acute inflammatory disease of the genitalia caused by herpes simplex virus ...this virus: type 1 and type 2. Apart from genitals, the virus can infect the ...
14
Herpes Simplex Virus Type 2 Vaccines: New Ground for Optimism?
... Another HSV-2 mutant with a deletion of ICP8, a gene required for viral DNA synthesis, reduced HSV-2 replication, disease severity, and the frequency of recurrent disease in the guinea pig ...An ...
9
Herpes simplex virus type II in a patient having Periodic Lateralized Epileptiform Discharges
... with Herpes Simplex Virus (HSV), periodic lateralized epileptic form discharges (PLEDs) are considered a specific finding on electroencephalogram ...
7
Frequency of Acyclovir Resistant Herpes Simplex Virus in Clinical Specimens and Laboratory Isolates
... of HSV will increase, we have sought to develop additional baseline information on the prev- alence of resistant mutants in clinical samples and isolates prepared from those ...of HSV to antivirals were ...
5
Application of Competitive PCR to Cerebrospinal Fluid Samples from Patients with Herpes Simplex Encephalitis
... Herpes simplex encephalitis (HSE) is associated with high rates of mortality and morbidity ...infectious virus in brain biopsy tissue suggested that larger amounts of virus were predictive of ...
6
Induction of Nucleic Acid Damage in Viral Genomes using Riboflavin in Combination with UV Light
... on Herpes simplex virus (HSV), Vesicular stomatitis virus (VSV) and Polio virus classified as enveloped and non-enveloped DNA and RNA viruses, ...
6
Pangaea and the Out-of-Africa Model of Varicella-Zoster Virus Evolution and Phylogeography
... cella virus is Old World simian varicella virus ...follows: HSV-1, herpes simplex virus 1; HSV-2, herpes simplex virus 2; SA-8, simian agent 8; HVB, ...
8
Herpes simplex virus infects most cell types in vitro: clues to its success
... during HSV entry ...in HSV entry and plaque forma- ...Interestingly, HSV infection resulted in the upregulation of syndecan-1 and syndecan-2 expression on the cell surface and at the protein level ...
11
A Gene Capable of Blocking Apoptosis Can Substitute for the Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene and Restore Wild-Type Reactivation Levels
... ptosis activity. Although the LR gene of BHV-1 is clearly the homologue of the HSV-1 LAT gene, there are some important differences. For example, the primary LAT transcript is 8.3 kb (45), whereas the primary LR ...
12
Inhibition of Curcumin Treated Herpes Simplex Virus 1 and 2 in Vero Cells
... the HSV rep- lication cycle. Both HSV-1 and HSV-2 viruses used in this study contain the sequence for green fluorescent protein (see materials and methods), thus the localization of GFP was observed ...
12