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human adipose-derived stem cells

Fibroblast growth factor-2 stimulates proliferation of human adipose-derived stem cells via Src activation

Fibroblast growth factor-2 stimulates proliferation of human adipose-derived stem cells via Src activation

... of human adipose-derived stem cells (hASCs) Human adipose tissue was harvested from the abdominal subcutis of patients who underwent plastic ...of adipose tissue ...

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Antioxidative fullerol promotes osteogenesis of human adipose-derived stem cells

Antioxidative fullerol promotes osteogenesis of human adipose-derived stem cells

... Abstract: Antioxidants were implicated as potential reagents to enhance osteogenesis, and nano-fullerenes have been demonstrated to have a great antioxidative capacity by both in vitro and in vivo experiments. In this ...

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Expression analysis of human adipose-derived stem cells during in vitro differentiation to an adipocyte lineage

Expression analysis of human adipose-derived stem cells during in vitro differentiation to an adipocyte lineage

... of adipose tissue ...these cells readily accumulate lipid upon ...[14] adipose tissues have been examined for transcriptional profile comparisons with human adipose ...of human ...

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Human adipose-derived stem cells for the treatment of intracerebral hemorrhage in rats via femoral intravenous injection

Human adipose-derived stem cells for the treatment of intracerebral hemorrhage in rats via femoral intravenous injection

... Phenotypically, the huADSC expressed immunophenotypes of CD29, CD44, CD73, CD90, CD105, and HLA class I that are characteristic markers of MSCs. The huADSC also expressed CD34 very weakly, as reported by others [29, 30]. ...

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Hypoxia Promotes Growth and Viability of Human Adipose-Derived Stem Cells with Increased Growth Factors Secretion

Hypoxia Promotes Growth and Viability of Human Adipose-Derived Stem Cells with Increased Growth Factors Secretion

... MSCs, adipose derived stem cells (ASCs) have become an attractive source for cell therapy due to their relative abundance and readily accessibility ...years, adipose tissue can be ...

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Osteogenic potential of induced pluripotent stem cells from human adipose-derived stem cells

Osteogenic potential of induced pluripotent stem cells from human adipose-derived stem cells

... Tumorigenicity is a major concern and limitation in cell-based transplantation and tissue engineering. The differentiated cells following specific induction eliminate the pluripotency and were guided into a less ...

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The roles of integrin β1 in phenotypic maintenance and dedifferentiation in chondroid cells differentiated from human adipose derived stem cells

The roles of integrin β1 in phenotypic maintenance and dedifferentiation in chondroid cells differentiated from human adipose derived stem cells

... We used real-time RT-PCR to detect the expression of SOX9, COL II, COL I, and Aggrecan genes from the following nine groups: ADSCs group (ADS), normal chondrocytes group (NC), 3-day differentiation group (3DD), 6-day ...

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Human adipose-derived stem cells inhibit bioactivity of keloid fibroblasts

Human adipose-derived stem cells inhibit bioactivity of keloid fibroblasts

... ADSC: Adipose-derived stem cell; CM: Conditioned medium; COL1: Collagen 1; COL3: Collagen 3; DAB: 3,3 ′ -Diaminobenzidine; DMEM: Dulbecco ’ s modified Eagle ’ s medium; ECL: Enhanced ...

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From bench to bedside: use of human adipose-derived stem cells

From bench to bedside: use of human adipose-derived stem cells

... donors, potentially preselected based on their cytokine and cell marker expression profile to improve the therapeutic potential of the cells. A number of companies are currently producing allogeneic “off-the-shelf ...

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Obesity inhibits the osteogenic differentiation of human adipose derived stem cells

Obesity inhibits the osteogenic differentiation of human adipose derived stem cells

... days, cells undergoing osteogenic differ- entiation in ODM or CDS-ODM were fixed in 10 % for- malin for 1 h, washed with distilled water, and stained with 1 % Alizarin Red (pH ...

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Plasticity of human adipose derived stem cells – relevance to tissue repair

Plasticity of human adipose derived stem cells – relevance to tissue repair

... Previous studies had demonstrated expression of pluripotent markers in pADSCs and suggested that this may underlie their plasticity (Guasti et al., 2012, Park and Patel, 2010). In order to establish whether this pattern ...

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Transdifferentiation of human adipose-derived mesenchymal stem cells into oligodendrocyte progenitor cells

Transdifferentiation of human adipose-derived mesenchymal stem cells into oligodendrocyte progenitor cells

... Background: Stem cell-based therapy is a new method for the treatment of neurodegenerative diseases such as multiple sclerosis ...(MS). Human adipose-derived stem cells (hADSCs) ...

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Comparison of the therapeutic effects of human and mouse adipose-derived stem cells in a murine model of lipopolysaccharide-induced acute lung injury

Comparison of the therapeutic effects of human and mouse adipose-derived stem cells in a murine model of lipopolysaccharide-induced acute lung injury

... stromal cells provide unique opportunities for developing novel treatments for a large array of inflammatory diseases, because MSCs possess potent immunomodulatory properties and are often considered to be ...

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ADIPOSE-DERIVED STEM CELLS IN TISSUE ENGINEERING: LABORATORY TO BEDSIDE

ADIPOSE-DERIVED STEM CELLS IN TISSUE ENGINEERING: LABORATORY TO BEDSIDE

... diseases derived from animals if ASCs are employed clinically in ...the human ASCs ...of human skeletal-derived MSCs when cultured in human serum and fetal bovine serum ...in ...

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Mesenchymal stem cells (MSCs) as skeletal therapeutics–an update

Mesenchymal stem cells (MSCs) as skeletal therapeutics–an update

... marrow derived MSCs when grown in an in-vitro three dimensional tumor microenvironment enhanced the growth of ERα positive breast cancer cell lines (T47D, BT474 and ZR-75-1) without affecting the ERα negative ...

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Adipose-derived stromal cells in regulation of hematopoiesis

Adipose-derived stromal cells in regulation of hematopoiesis

... adult human adipocyte pre- cursors from adipose tissue were studied in the early 1970s ...These cells were ex- tracted from diverse anatomical sites, such as superficial abdominal areas, the upper ...

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Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis

Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis

... stromal cells, also referred to as mesen- chymal stromal/stem cells (MSCs), have been used for cell therapy and in tissue engineering because of their ability to differentiate into multiple ...

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Exosomes secreted by adipose derived mesenchymal stem cells regulate type i collagen metabolism in fibroblasts from women with stress urinary incontinence

Exosomes secreted by adipose derived mesenchymal stem cells regulate type i collagen metabolism in fibroblasts from women with stress urinary incontinence

... Methods: Periurethral vaginal wall tissues of postmenopausal women with or without SUI were collected during transvaginal surgical procedures. Primary fibroblasts were cultured from periurethral vaginal wall tissues, and ...

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Human Adipose Tissue-Derived Mesenchymal Stem Cells in Parkinson’s Disease: Inhibition of T Helper 17 Cell Differentiation and Regulation of Immune Balance Towards a Regulatory T Cell Phenotype

<p>Human Adipose Tissue-Derived Mesenchymal Stem Cells in Parkinson&rsquo;s Disease: Inhibition of T Helper 17 Cell Differentiation and Regulation of Immune Balance Towards a Regulatory T Cell Phenotype</p>

... Th17 cells, as well as increased secretion of IL-17 in the serum of patients with PD (Cen et al, 2017; Park et al, ...Th17 cells leads to tissue damage due to the production of the neurotoxic ...

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Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin

Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin

... biological function of MSCs derived from human chori- onic villus, human bone marrow, and human adipose. Although MSCs from different source share similar anti- gens, their repair ...

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