Human bocavirus
Human Bocavirus Infection in Children with Acute Respiratory Infection in Nairobi, Kenya
... Background: Acute respiratory infection (ARI) is a leading cause of morbidity and mortality in children under five years of age in developing countries with viruses contributing significantly to this problem. The ...
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Molecular detection and phylogenetic analysis of Kenyan human bocavirus isolates
... the human population and environment resulting in the resurgence and emergence of new viral ...include human bocavirus, metapneumovirus, and human ...[15], human bocavirus has ...
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Human Bocavirus Can Be Cultured in Differentiated Human Airway Epithelial Cells
... a human bocavirus was discovered in children with respiratory tract ...pseudostratified human airway epithelium. This cell culture system mimics the human airway environment and facilitates ...
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Simultaneous atelectasis in human bocavirus infected monozygotic twins: was it plastic bronchitis?
... of human bocavirus-induced plastic bronchitis has previously been reported only once, in a 14- month-old, previously healthy patient ...of human airway epithelial cells, resulting in replication of ...
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Development of a Real Time PCR Assay for Detecting and Quantifying Human Bocavirus 2
... Human bocavirus 2 (HBoV2) is a parvovirus that has been recently identified in stool samples from children. Any association between the virus and clinical disease is unclear. A rapid, reliable diagnostic ...
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Human Bocavirus Capsid Structure: Insights into the Structural Repertoire of the Parvoviridae
... Human bocavirus (HBoV), a newly discovered member of the family Parvoviridae, was originally isolated in randomly selected nasopharyngeal aspirates ...as human rhinovirus and Strepto- coccus ...of ...
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Human bocavirus (HBoV) in children with respiratory tract infection by enzyme linked immunosorbent assay (ELISA) and qualitative polymerase chain reaction (PCR)
... undescribed human parvovirus in respiratory secre- tions from children with respiratory tract disease in ...genus Bocavirus (subfamily, Parvovirinae; family, Parvoviridae) and was most closely related to ...
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Hypertrophic Adenoid Is a Major Infection Site of Human Bocavirus 1
... Human bocavirus 1 (HBoV1) is associated with respiratory infections worldwide, mainly in children. Similar to other parvovi- ruses, it is believed that HBoV1 can persist for long periods of time in humans, ...
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DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells
... ABSTRACT Human bocavirus 1 (HBoV1), an emerging human-pathogenic respiratory virus, is a member of the genus Bocaparvovirus of the Parvoviridae ...In human airway epithelium air-liquid ...
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The 5′ Untranslated Region of Human Bocavirus Capsid Transcripts Regulates Viral mRNA Biogenesis and Alternative Translation
... ABSTRACT The capsid mRNA transcripts of human bocavirus 1 (HBoV1) can be generated by alternative splicing from the mRNA precursor transcribed from the P5 promoter. However, the alternative translation ...
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Alternative Polyadenylation of Human Bocavirus at Its 3′ End Is Regulated by Multiple Elements and Affects Capsid Expression
... ABSTRACT Alternative processing of human bocavirus (HBoV) P5 promoter-tran- scribed RNA is critical for generating the structural and nonstructural protein- encoding mRNA transcripts. The regulatory ...
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In Vitro Modeling of Human Bocavirus 1 Infection of Polarized Primary Human Airway Epithelia
... Human bocavirus 1 (HBoV1) is an emerging human-pathogenic respiratory virus. We characterized two important features of HBoV1 infection in polarized primary human airway epithelia (HAE). ...
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Human Bocavirus 1 Is a Novel Helper for Adeno-associated Virus Replication
... ABSTRACT Human bocavirus 1 (HBoV1) is an autonomous parvovirus that infects well-differentiated primary human airway epithelia (HAE) in ...In human embry- onic kidney HEK293 cells, the ...
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Acute human bocavirus 1 infection in child with life threatening bilateral bronchiolitis and right sided pneumonia: a case report
... Background: Human bocavirus 1 is a commonly detected human ...shown human bocavirus 1 as a pathogen in association with acute respiratory tract infections in ...because human ...
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Identification and Functional Analysis of Novel Nonstructural Proteins of Human Bocavirus 1
... 5. Nascimento-Carvalho CM, Cardoso MR, Meriluoto M, Kemppainen K, Kantola K, Ruuskanen O, Hedman K, Soderlund-Venermo M. 2012. Human bocavirus infection diagnosed serologically among children ad- mitted to ...
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Phylogenic analysis of human bocavirus detected in children with acute respiratory infection in Yaounde, Cameroon
... During the past two decades, new molecular techniques have contributed to the discovery of many viruses. This was the case in September 2005 with the discovery of the Human Bocavirus (HBoV) by a Swedish ...
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Nonstructural Protein NP1 of Human Bocavirus 1 Plays a Critical Role in the Expression of Viral Capsid Proteins
... A novel chimeric parvoviral vector, rAAV2/HBoV1, in which the recombinant adeno-associated virus 2 (rAAV2) genome is pseu- dopackaged by the human bocavirus 1 (HBoV1) capsid, has been shown to be highly ...
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High prevalence of antibodies against polyomavirus WU, polyomavirus KI, and human bocavirus in German blood donors
... Background: DNA of the polyomaviruses WU (WUPyV) and KI (KIPyV) and of human bocavirus (HBoV) has been detected with varying frequency in respiratory tract samples of children. However, only little is known ...
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Phylogenetic and recombination analysis of human bocavirus 2
... Human bocavirus (HBoV), HBoV2, HBoV3, and HBoV4 have been discovered recently ...genus Bocavirus in the subfamily Parvovir- inae of the family Parvoridae, among which the human parvovirus B19 ...
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Analysis of cis and trans Requirements for DNA Replication at the Right-End Hairpin of the Human Bocavirus 1 Genome
... Human bocavirus 1 (HBoV1) causes acute respiratory tract infections in young children. The duplex HBoV1 genome replicates in HEK293 cells and produces progeny virions that are infectious in ...
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