human brain microvascular endothelial cells
In vitro characterization of pralidoxime transport and acetylcholinesterase reactivation across MDCK cells and stem cell-derived human brain microvascular endothelial cells (BC1-hBMECs)
... the brain we stud- ied permeability of 2-PAM in four cell lines: MDCKII, MDCKII-MDR1, MDCKII-FLuc-ABCG2, and BC1- ...epithelial cells (MDCKs) are widely used for in vitro assessment of brain ...
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Zika Virus Persistently Infects and Is Basolaterally Released from Primary Human Brain Microvascular Endothelial Cells
... During human infections, ZIKV is found in a variety of body fluids (tears, saliva, semen, cervical mucus, and urine) that facilitate viral replication and dissemination, and ZIKV damages placen- tal, corneal, and ...
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Post mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells
... One of the novel findings in our study is the isolation of B. mandrillaris from the post-mortem CSF sample of the infected patient. To our knowledge, this is the first report describing the CSF isolation of B. ...
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Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs)
... To evaluate the expression and localization of tight junc- tion and cytoskeletal proteins, monolayers were stained for claudin-5, occludin, zonula occludens 1 (ZO-1), and F-actin (Fig. 8). Claudin-5 and occludin are ...
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Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells
... neoformans cells can adhere to the surface of HBMEC, as the CD44 molecules are still ...fungal cells was significantly reduced in Cav-1 siRNA-treated HBMEC (Figure 3B, lane 3), suggesting that ...neoformans ...
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The Meningococcal Cysteine Transport System Plays a Crucial Role in Neisseria meningitidis Survival in Human Brain Microvascular Endothelial Cells
... from human hosts appears to be important for meningococcal pathogenesis because the availability of the nutrient supply needed by facultative meningococci to cause IMD is limited in the human environment ...
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Profiling the proteomic inflammatory state of human astrocytes using DIA mass spectrometry
... Primary human brain microvascular endothelial cells (HBMECs) (ScienCell) were grown in complete endothe- lial cell growth medium (EGM-2MV) (Lonza) while pri- mary human ...
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Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus
... HCMV-infected human brain vascular pericytes as evidenced by several ...mRNA. Brain pericytes were fully permissive for CMV lytic replication after 72 to 96 hours in culture compared to human ...
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Angiotensin receptors and β catenin regulate brain endothelial integrity in malaria
... blood cells (Pf-iRBCs) to endothelial cells in the brain, disruption of the blood-brain barrier, and cerebral ...the endothelial disruptions underlying this complication, which ...
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The complete genome sequence of Cronobacter sakazakii ATCC 29544T, a food-borne pathogen, isolated from a child’s throat
... with the invasion of human brain microvascular endothelial cells (BMECs). In addition, gene clusters for siderophore production (iucABCD/iutA) and the related transport system (eitCBAD) ...
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Group B streptococcal β hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis
... between endothelial cells and microbial gene ...the human meningeal pathogen group B Streptococcus (GBS) and the organism’s major virulence factors, the exopolysaccharide capsule and the ...
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CXC and CC Chemokine Receptors on Coronary and Brain Endothelia
... Materials and Methods: The expression of chemokine receptors in human brain microvascular endothelial cells (BMVEC) and coronary artery endothelial cells (CAEC).. in vitro and cryostat s[r] ...
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A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier
... of human BBB microvascular endothelial cells and to apply this model to the study of RNA ...used human brain microvascular endothelial cells (HBMEC) (9), an ...
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Blood brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease
... cross human brain microvascular endothelial cells (BMECs), a human blood-brain barrier (BBB) model system, at much greater efficiency than do ...of human BMECs was ...
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Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D
... the cells were switched to dhBMEC medium for 2 ...of endothelial cell serum-free medium supplemented with 1% platelet- poor plasma-derived human serum (Sigma), 2 ng mL ...
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ATF4 is a novel regulator of MCP-1 in microvascular endothelial cells
... in human monocytes/macrophages ...retinal endothelial and Müller cells, respect- ively ...vascular endothelial cells in the brain and the ...
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Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co cultured with Plasmodium falciparum field isolates
... blood cells were selected for their viabil- ity, because pRBC from patients having self-medicated (and who rarely inform their physician) do not grow well in ...
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Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF
... Elevated levels of cytokines/chemokines contribute to increased neuroinvasion of human immunodeficiency virus type 1 (HIV-1). Previous work showed that lipopolysaccharide (LPS), which is present in the plasma of ...
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Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease
... vascular endothelial cell growth factor mRNA compared to ...both brain and retinal pericytes were more permissive for HCMV infection than other cellular components of the BBB (blood-brain barrier) ...
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Intercellular adhesion molecule 1 and CD36 synergize to mediate adherence of Plasmodium falciparum infected erythrocytes to cultured human microvascular endothelial cells
... CHO cells (9, 10), amelanotic melanoma cells (7, 8, 25, 26), and human umbilical endothelial cells (HU- VEC) (10, ...fashion. Human dermal microvascular endothelial ...
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