Human Breast Cancer
Original Article Hyaluronan synthase 2 overexpression is correlated with the tumorigenesis and metastasis of human breast cancer
... for breast cancer [35]. Knockdown of HYAL1 expression in breast cancer cells resulted in decreased cell growth, adhesion, invasion and angiogenesis ...inhibited breast cancer ...
14
Is MMTV associated with human breast cancer? Maybe, but probably not
... with human breast cancer, it does not explain some of the published HMTV sequence ...many human HMTV sequences are very similar or identical to murine MMTV sequences, there are still quite a ...
10
The Role of miR-526b in COX-2 Mediated Human Breast Cancer Progression and Induction of Stem-Like Phenotype Via EP4 Receptor Signaling
... Previous work in our lab by Majumder et al. (2012) established that stable transfection and over-expression of the COX-2 gene in MCF-7 (ER+, HER2-, COX-2-) and SKBR-3 (ER-, HER2+, COX-2-) human breast ...
136
Characterization of human breast cancer epithelial cells (HBCEC) derived from long term cultured biopsies
... (Fig. 4B) and with normal post-selection HMEC of pas- sage 16 (Fig. 5), respectively. Incubation with a single dose of 1 μM (blue bars) and 125 nM (red bars) of Taxol, epothilones or the anthracyclins and combinations ...
12
Cascaded Electrochemiluminescence Signal Amplifier for the Detection of Telomerase Activity from Tumor Cells and Tissues
... lung cancer cell line, A549; human breast cancer cell line, MCF7; and human liver cancer line, HepG2) were added to the elongation system, and the products were assessed by ...
9
Original Article Bmi-1 regulates epithelial-to-mesenchymal transition to promote migration and invasion of breast cancer cells
... of human mammary epithelial cells and tumor cell lines (MDA-MB-468, T47D, BT474, MCF-7, MDA-MB-231, ...in breast cancer cells, especially over- expressed in metastatic cancer cells (Figure ...
8
KLF4α stimulates breast cancer cell proliferation by acting as a KLF4 antagonist
... in human breast cancer cells Unresolved data on the role of KLF4 during breast carcinogenesis [4], as well as the identification of KLF4α, a KLF4 isoform, as a tumor-promoting gene in ...
14
Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylated- p53-induced signals
... in human breast cancer samples ...the breast cancer tissues of heavy smokers (n=7, ...in breast cancer patients who were heavy ...for cancer prevention and ...
16
Characterization of a P-Rex1 gene signature in breast cancer cells
... in human breast cancer, we first performed a comparative analysis of PREX1 and MMP10 expression in paired breast carcinomas and normal tissue, using the TCGA (The Cancer Genome Atlas) ...
14
Anticancer effect of the five surfactin isomers produced during cheonggukjang fermentation by Bacillus pumilus HY1 isolated from Korean traditional fermented soy sauce
... cheonggukjang against the cancer cell lines MCF-7 (human breast cancer line) and Caco-2.. (human intestinal cancer line) was studied. Materials and methods.[r] ...
33
Glucose Metabolism in Breast Cancer and its Implication in Cancer Therapy
... of human breast cancer ...MDA-MB-468 breast cancer cells could be enhanced by down-regulation of anti-apoptotic factors such as XIAP, cIAP-1 and Akt, and up-regulation of apoptotic ...
19
Wnt signaling in breast cancer: have we come full circle?
... in breast cancer In addition to the oncogenic effects of Wnt genes in mouse mammary cancer, there is further evidence that activation of the canonical Wnt signaling pathway pro- motes tumorigenesis ...
5
Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells
... four cancer cell lines – human gastric cancer cell line MGC803, human lung cancer cell line A549, human prostate cancer cell line PC-3, and human breast ...
9
Downregulation of FOXO6 in breast cancer promotes epithelial–mesenchymal transition and facilitates migration and proliferation of cancer cells
... in breast cancer. To further detect the effect of FOXO6 on EMT, human breast cancer MCF-7 cells were transfected with vector or FOXO6 plasmid, or scramble siRNA or FOXO6 siRNA, ...in ...
12
Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer
... to cancer pro- ...and breast cancer cell lines into functionally distinct subtypes, described as Luminal, Basal A, and Basal ...SUM149PT breast cancer cells expressed comparatively low ...
14
Establishment and molecular characterization of breast cancer mesenchymal stem cell line derived from human non metastasis breast cancer tumor
... Breast cancer remains a leading cause of mor- bidity and mortality in women mainly because of the propensity of primary breast tumors to me- ...properties. Breast cancer-initiating ...
8
Phytochemical analysis and antiproliferative studies of various extracts of mollugo cerviana
... Normal Human Dermal Fibroblast cells (NHDF), Human Cervical Cancer cells (HeLa), Human Liver Cancer cells (HepG2), Human Lung cancer cells (A549) and Human ...
5
Mouse models of breast cancer in preclinical research
... Breast cancer remains the second leading cause of cancer death among woman, worldwide, despite advances in identifying novel targeted therapies and the development of treating ...of breast ...
6
IN VITRO ANTICANCER ACTIVITY OF Carica papaya (FRUITLESS TYPE) EXTRACT AGAINST HUMAN MCF-7 CELL LINE
... Breast cancer is the most common cancer in women ...of cancer where cells in the breast divide and grow without normal ...is breast cancer cell lines isolated in 1970 from ...
7
Honors Thesis FINAL**.docx
... To better understand what defines the basal-like subtype, the Perou lab undertook gene expression analysis of primary human tumors, human breast cancer cell lines, and mouse mammary tumors. ...
27