Human bronchial epithelium cells
PM2.5 induces autophagy-mediated cell death via NOS2 signaling in human bronchial epithelium cells
... in human bronchial epithelium ...trigger human lung cell aging, as abnormal cell dysfunction always along with cell aging ...in human bronchial epithelium cells and ...
8
Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro
... mTHP-1 cells (differentiated monocyte cell line) [21]. Particle concentrations in this study were kept well below cytotoxic concentrations. For exposure, NP sus- pensions (unloaded CTC NP, CTC pGFP NP and CTPPC ...
10
Rhinovirus infection induces cytotoxicity and delays wound healing in bronchial epithelial cells
... exposed cells [15]; biopsy data show that in human RV infection epithelial inflam- mation, potentially resulting from infection, is patchy [27,36]: there has been, however, no direct comparison between ...
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Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation
... bronchial segment, and 5 mL control (normal saline) was instilled in a contralateral lower lobe bronchial segment. Photographs were taken of the segments instilled, to guide subsequent bronchoscopy as ...
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Multiwalled carbon nanotubes induce altered morphology and loss of barrier function in human bronchial epithelium at noncytotoxic doses
... from cells treated with the control vehicle and eight treated with MWCNT 3 μ g/mL) were collapsed into two-dimensional summation images of the 12 μ M-thick section in the middle of each ...
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Ingraft chimerism in lung transplantation - a study in a porcine model of obliterative bronchiolitis
... adult human lung has a capacity to renew itself by extrapulmonary cells [26] and it has been demonstrated that re-epithelisation with recipient-derived epithelium protects allografts from ...
7
Human bronchus and intestine express the same mucin gene
... The amino acid and sugar composition of mucins from various organs is similar but not identical. This could arise by one or more of the following: organ-specific processing of a single core protein, organ-specific ...
7
Bronchial epithelium in children: a key player in asthma
... original bronchial RBM thickness and level of eosinophil infiltration after 1-year of treatment with anti-IgE, thus emphasising the possible role of omalizumab in affecting airway remodelling in severe persistent ...
12
Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines
... in human airways and this cytokine is involved in the local immune response to a bacterial stimulus in ...in human airways and this cytokine potentiates chemotactic responses in human ...17 ...
11
Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels
... Immunostaining of CFTR in formalin fixed, paraffin embedded 4 μm thick sections was performed using the Ventana Benchmark LT System and the universal fast red and DAB (red and brown color, respectively) detection ...
9
Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients
... in bronchial epithelial cells derived from COPD subjects, demonstrating that these cells are undergoing EMT ...normal bronchial epithelial cells responded to cell culture ...
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Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung
... 1A. Epithelium of a bronchus is positive for claudin-1 (ar- ...Epithelial cells of developing bronchioles are positive for claudin-3 ...epithelial cells of a bronchiole. Scale bar = 25 μm. 1D-1E. ...
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Vulnerability of the human airway epithelium to hyperoxia Constitutive expression of the catalase gene in human bronchial epithelial cells despite oxidant stress
... in human bronchial epithelial cells in response to ...the human catalase gene showed features of a "house-keeping" gene (no TATA box, high GC content, multiple CCAAT boxes, ...
7
Successful Readministration of Adeno-Associated Virus Vectors to the Mouse Lung Requires Transient Immunosuppression during the Initial Exposure
... the bronchial epithelium following adeno-associated virus (AAV) vector administration to the rabbit ...marker-positive cells in the epithelial population in rabbits by evaluating AAV vector ...
11
Respiratory Syncytial Virus Infection, TLR3 Ligands, and Proinflammatory Cytokines Induce CD161 Ligand LLT1 Expression on the Respiratory Epithelium
... (MAIT) cells, and type 2 innate lymphoid ...epithelial cells following respiratory-virus infection as a mechanism by which respiratory-virus infection could promote activation of proinflammatory ...primary ...
8
Gene and protein expression of tlr 9 with lipopolysaccharide in human bronchial epithelial cells
... The study conducted here was to investigate the gene and protein expression of Toll like receptor 9 when human bronchial epithelial cells were induced by lipopolysaccharide. TLRs are pattern ...
7
Anti-inflammatory effects of antibacterials on human bronchial epithelial cells
... Airway epithelial cells have been shown to be of crucial importance in the pathogenesis of inflammatory airway diseases [11]. In addition to antimicrobial activities, mac- rolides directly affect pulmonary host ...
8
MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease
... Peripheral human lung tissue was obtained from 3 types of subjects (Thoracic Surgery and Pathology Ser- vices of the University General Consortium Hospital and University and Polytechnic Hospital La Fe, Spain): A) ...
18
Comparison of paired human nasal and bronchial airway epithelial cell responses to rhinovirus infection and IL-13 treatment
... and bronchial epi- thelial cells under submerged and ALI ...cultured cells decreases viral ...goblet cells induced by IL-13, while IP-10 production may come from non-goblet cells ...
10
Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD
... (P,0.01; Figure 2D). Moreover, MLI measurement was dramatically elevated in CS-exposed mice (P,0.001; Figure 2E and F). Levels of IL-6 and KC in BALF were determined by ELISA. Compared with controls, levels of IL-6 ...
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