human coronavirus
Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors
... respiratory coronavirus (CRCoV), bovine coronavirus, (BCoV) and human coronavirus OC43 (HCoV-OC43), these viruses differ in species ...employ human leukocyte antigen class I (HLA-1) as ...
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Plaque assay for human coronavirus NL63 using human colon carcinoma cells
... Background: Coronaviruses cause a broad range of diseases in animals and humans. Human coronavirus (hCoV) NL63 is associated with up to 10% of common colds. Viral plaque assays enable the characterization ...
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Structural Characterization of Human Coronavirus NL63 N Protein
... ABSTRACT Coronaviruses are responsible for upper and lower respiratory tract in- fections in humans. It is estimated that 1 to 10% of the population suffers annually from cold-like symptoms related to infection with ...
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Complete Genomic Sequence of Human Coronavirus OC43: Molecular Clock Analysis Suggests a Relatively Recent Zoonotic Coronavirus Transmission Event
... Coronaviruses are enveloped, positive-stranded RNA viruses with a genome of approximately 30 kb. Based on genetic similarities, coronaviruses are classified into three groups. Two group 2 coronaviruses, human ...
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Human Coronavirus EMC Does Not Require the SARS Coronavirus Receptor and Maintains Broad Replicative Capability in Mammalian Cell Lines
... new human coronavirus (hCoV-EMC) has emerged very recently in the Middle ...the human respiratory tract limited the spread of ...of human ACE2 (hACE2) conferred permissiveness and replication ...
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Evidence for an Ancestral Association of Human Coronavirus 229E with Bats
... of human coronavirus 229E (HCoV-229E) exist in African ...and human viruses. According to taxonomic criteria, human, alpaca, and bat viruses form a single CoV species showing evidence for ...
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Biosynthesis, purification, and characterization of the human coronavirus 229E 3C-like proteinase.
... the human coronavirus 229E 3C-like proteinase in Escherichia coli and the enzymatic properties, inhibitor profile, and substrate specificity of the purified ...in coronavirus 3C-like proteinases for ...
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Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS Coronavirus
... novel human coronavirus (HCoV-EMC) was recently identified in the Middle East as the causative agent of a severe acute respiratory syndrome (SARS) resembling the illness caused by SARS coronavirus ...
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Evolutionary History of the Closely Related Group 2 Coronaviruses: Porcine Hemagglutinating Encephalomyelitis Virus, Bovine Coronavirus, and Human Coronavirus OC43
... of coronavirus ORF1b amino acid ...includes human coronavirus 229E (HCoV-229E, AF304460), human coronavirus NL63 (HCoV-NL63, AY567487), porcine epidemic diar- rhea virus strain CV777 ...
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Human Coronavirus NL 63 Infections in Children: a 1 Year Study
... recently, human metapneumovi- rus virus (hMPV) has also been identified as an important respiratory pathogen in children ...new human coronavirus (HCoV), NL63 (HCoV-NL63), was identified in clinical ...
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Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry
... primary human bronchial/tra- cheal epithelial (HBTE) cells using an air-liquid interface (ALI) culture system, as de- scribed previously (15, ...of human airway epithelium ...with human ...
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Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63
... syndrome coronavirus (SARS- CoV) emerged in 2002 in Guangdong province, China, and its subsequent spread to 26 countries was associated with 8,096 infections and 774 deaths ...The human coronavirus ...
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Development of a Nucleocapsid-Based Human Coronavirus Immunoassay and Estimates of Individuals Exposed to Coronavirus in a U.S. Metropolitan Population
... feline coronavirus nucleocapsid indicates that genus- and group-specific cross- reactivity cannot completely explain the correlation between antibody levels to the different human coronavirus ...of ...
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Characterization of a human coronavirus (strain 229E) 3C-like proteinase activity.
... of human coronavirus (HCV) 229E encodes a large polyprotein that contains domains with motifs characteristic of both papain-like cysteine proteinases and proteinases with homology to the 3C proteinase of ...
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Human Coronavirus 229E Remains Infectious on Common Touch Surface Materials
... but human coronavirus 229E (HuCoV- 229E) did not persist for above a few hours on surfaces ...infectious human coronavirus 229E persisted on 5 surface materials, com- mon to communal and ...
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Human Coronavirus NL63 Utilizes Heparan Sulfate Proteoglycans for Attachment to Target Cells
... Human coronavirus NL63 was first identified ⬃ 10 years ago. Since then, a number of research groups have studied this patho- gen, resulting in the publication of a considerable number of pa- pers about the ...
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Infectivity of human coronavirus strain 229E
... Discrete foci of infection were observed from 8 to 16 h after infection in cells infected with high dilutions of human coronavirus 229E; each fluorescent focus corresponded to a single v[r] ...
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Entry of Human Coronavirus NL63 into the Cell
... ABSTRACT The first steps of human coronavirus NL63 (HCoV-NL63) infection were previously described. The virus binds to target cells by use of heparan sulfate pro- teoglycans and interacts with the ACE2 ...
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Protease-Mediated Entry via the Endosome of Human Coronavirus 229E
... Human coronavirus 229E, classified as a group I coronavirus, utilizes human aminopeptidase N (APN) as a receptor; however, its entry mechanism has not yet been fully ...murine ...
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Human Coronavirus NL63 and 229E Seroconversion in Children
... In 2004, the novel respiratory human coronavirus NL63 (HCoV-NL63) was identified, and subsequent research revealed that the virus has spread worldwide. HCoV-229E is a close relative of HCoV-NL63, and ...
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