Human coronavirus 229E
Comparative Host Gene Transcription by Microarray Analysis Early after Infection of the Huh7 Cell Line by Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus 229E
... syndrome-associated coronavirus (SARS-CoV) at the cellular level is unclear. No human cell line was previously known to be susceptible to both SARS-CoV and other human ...and human ...
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Human Coronavirus 229E Remains Infectious on Common Touch Surface Materials
... but human coronavirus 229E (HuCoV- 229E) did not persist for above a few hours on surfaces ...infectious human coronavirus 229E persisted on 5 surface materials, com- mon ...
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Evidence for an Ancestral Association of Human Coronavirus 229E with Bats
... of human coronavirus 229E (HCoV-229E) exist in African ...described 229E- related alpaca virus occupied an intermediate phylogenetic position between bat and human ...criteria, ...
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Biosynthesis, purification, and characterization of the human coronavirus 229E 3C-like proteinase.
... the human coronavirus 229E 3C-like proteinase in Escherichia coli and the enzymatic properties, inhibitor profile, and substrate specificity of the purified ...in coronavirus 3C-like ...
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Protease-Mediated Entry via the Endosome of Human Coronavirus 229E
... Human coronavirus 229E, classified as a group I coronavirus, utilizes human aminopeptidase N (APN) as a receptor; however, its entry mechanism has not yet been fully ...with 229E ...
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Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes
... of coronavirus gene ...within coronavirus genomes. The functions of coronavirus accessory proteins are largely unknown, how- ever, reverse genetic analyses of Mouse Hepatits Virus (MHV) and Feline ...
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Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry
... ABSTRACT Human coronavirus 229E (HCoV-229E), a causative agent of the common cold, enters host cells via two distinct pathways: one is mediated by cell surface pro- teases, particularly ...
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Human Coronavirus 229E Infects Polarized Airway Epithelia from the Apical Surface
... by human coronavirus 229E (HCoV- 229E), a common cause of respiratory tract ...of human airway epithelia, infection primarily occurred from the apical ...cultured human tracheal ...
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Persistent Infection of Human Oligodendrocytic and Neuroglial Cell Lines by Human Coronavirus 229E
... izing three clones for each cell line and infection. In certain cases, even amplicons obtained from different RT-PCRs were cloned and sequenced. No sequence differences between inde- pendent cloned amplicons were ...
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Coronavirus isolates SK and SD from multiple sclerosis patients are serologically related to murine coronaviruses A59 and JHM and human coronavirus OC43, but not to human coronavirus 229E.
... 1 Coronavirus Isolates SK and SD from Multiple Sclerosis Patients Are Serologically Related to Murine Coronaviruses A59 and JHM and Human Coronavirus OC43, but Not to Human Coronavirus 2[r] ...
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Processing of the Human Coronavirus 229E Replicase Polyproteins by the Virus-Encoded 3C-Like Proteinase: Identification of Proteolytic Products and Cleavage Sites Common to pp1a and pp1ab
... age assay. The expression plasmid pBS-T (11) facilitates the generation of synthetic RNAs with T7 RNA polymerase, and it provides each RNA with a translation start codon in an optimal context. Cloning of insert DNA into ...
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Involvement of Aminopeptidase N (CD13) in Infection of Human Neural Cells by Human Coronavirus 229E
... example, coronavirus-like particles were found in the brain of a patient with multiple sclerosis (MS) (45), although their size was later shown to be untypical of ...
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Human Coronavirus 229E Papain-Like Proteases Have Overlapping Specificities but Distinct Functions in Viral Replication
... Butterfield, J. Khattra, J. K. Asano, S. A. Barber, S. Y. Chan, A. Cloutier, S. M. Coughlin, D. Freeman, N. Girn, O. L. Griffith, S. R. Leach, M. Mayo, H. McDonald, S. B. Montgomery, P. K. Pandoh, A. S. Petrescu, A. G. ...
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Genome of porcine transmissible gastroenteritis virus.
... The coronavirus family, therefore, if it can be characterized by infectious bronchitis virus, mouse hepatitis virus TGEV, bovine coronavirus, and human coronavirus 229E, is a truely uniq[r] ...
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Quantitation of Antibody to Non Hemagglutinating Viruses by Single Radial Hemolysis: Serological Test for Human Coronaviruses
... To show the general application of the SRH test for antibodies to non-hemagglutinating viruses, it was applied to human coronavirus 229E, the mouse hepatitis virus coronaviruses, coxsack[r] ...
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Infectivity of human coronavirus strain 229E
... Discrete foci of infection were observed from 8 to 16 h after infection in cells infected with high dilutions of human coronavirus 229E; each fluorescent focus corresponded to a single v[r] ...
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Middle East Respiratory Syndrome Coronavirus Infection Mediated by the Transmembrane Serine Protease TMPRSS2
... authentic human coronavirus, 229E (HCoV-229E), proficient for infection of MRC-5 and WI-38 cells, was also tested in the virus entry assay in the presence of camostat, EST, or leu- ...
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Evaluation of Inapparent Nosocomial Severe Acute Respiratory Syndrome Coronavirus Infection in Vietnam by Use of Highly Specific Recombinant Truncated Nucleocapsid Protein-Based Enzyme-Linked Immunosorbent Assay
... other human coronaviruses is very low (32.7% be- tween SARS-CoV and human coronavirus OC43 and ...and human coronavirus 229E), a highly conserved motif (FYYLGTGP) occurs in the ...
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Mouse Hepatitis Virus Liver Pathology Is Dependent on ADP-Ribose-1″-Phosphatase, a Viral Function Conserved in the Alpha-Like Supergroup
... that coronavirus replicase gene products impact virus pathogenicity (7, 28, 33, ...of human coronavirus 229E (HCoV-229E), severe acute respiratory syndrome coronavirus ...
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Surveillance of Bat Coronaviruses in Kenya Identifies Relatives of Human Coronaviruses NL63 and 229E and Their Recombination History
... well-characterized human CoVs lie within these ...other human CoVs such as SARS-CoV and MERS-CoV all use terrestrial mammals rather than bats as intermediate hosts, which have an increased chance of contact ...
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