Human exfoliated deciduous teeth stem cells
In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice
... hepatocyte-like cells in vivo in animal models of hepatic failure ...of human MSCs into hepatocytes [27, 28]. In comparison with other human tissues, exfoliated de- ciduous teeth offer ...
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Stem Cells from Human Exfoliated Deciduous Teeth – Isolation, Long Term Cultivation and Phenotypical Analysis
... isolate stem cells from human exfoliated deciduous teeth (SHED), to cultivate them in vitro and to investigate their basic biological properties, phenotype and to compare our ...
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Therapeutic effects of stem cells from human exfoliated deciduous teeth on diabetic peripheral neuropathy
... Stem cells from human exfoliated deciduous teeth (SHED) have been isolated from naturally exfoliated deciduous teeth with the capacity to differentiate into ...
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Stem cells from human exfoliated deciduous teeth ameliorate type II diabetic mellitus in Goto-Kakizaki rats
... Materials and methods: We investigated the effects of SHED on the progression of T2DM in GK rats. SHED and bone marrow mesenchymal stem cells (BMSCs) were injected via the tail vein. Body weight, fasting ...
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In vivo and immunohistochemical study of dentin and pulp tissue regeneration in the root canal
... these cells have the advantages of not triggering immune rejection, responding to growth factors inherent in the host, and not incurring ethical or moral ...with stem-progenitor cells from apical ...
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Stem cells from human exfoliated deciduous teeth correct the immune imbalance of allergic rhinitis via Treg cells in vivo and in vitro
... To investigate the underlying mechanism of the SHED immunomodulatory effect, we carried out coculture ex- periments of MSCs with human peripheral blood mono- nuclear cells (PBMCs). PBMCs were isolated from ...
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Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome
... Total RNA was extracted from the cells using an RNAeasy Mini Kit (Qiagen, Hilden, Germany). First-strand cDNA was synthesized using a ReverTra Ace qPCR RT Master Mix with gDNA Remover (Toyobo, Osaka, Japan). The ...
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Basic fibroblast growth factor regulates phosphate/pyrophosphate regulatory genes in stem cells isolated from human exfoliated deciduous teeth
... primary teeth. Expression of mesenchymal and hematopoietic stem cell surface markers was evaluated using flow ...isolated cells expressed MSC markers, CD44, CD90, and CD105 ...hematopoietic ...
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Induced in vitro differentiation of neural like cells from human exfoliated deciduous teeth derived stem cells
... of stem cells from SHED. These cells are highly proliferative MSCs, located in dental pulp and potentially derived from neural crest cells, may be an optimal source of postnatal stem ...
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A novel method for banking stem cells from human exfoliated deciduous teeth: lentiviral TERT immortalization and phenotypical analysis
... dental stem cells such as SHED will ultimately enter an irrevers- ible proliferation-arrested state referred to as replicative senescence after long term in vitro culture under culture stresses, such as ...
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Mineral trioxide aggregate affects cell viability and induces apoptosis of stem cells from human exfoliated deciduous teeth
... The clinically high success rate for MTA pulp capping or pulpotomy may be due to tissue homeostasis in vivo, and is likewise able to reduce the initially high concen- trations of calcium hydroxide and thus alkalinity [8, ...
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Stem cells from human exfoliated deciduous teeth as an alternative cell source in bio-root regeneration
... follicle cells (DFCs) from the impacted third molar, confirming its mesenchymal source and multidifferentiation capability in vitro ...mesenchymal stem cells (MSCs) that are present in developing ...
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From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells
... mesenchymal stem cells (MSCs) and epithelial stem cells play essential roles in tissue repair and ...epithelial stem cells can be isolated from adult human oral tissues, ...
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Exosomes secreted by stem cells from human exfoliated deciduous teeth contribute to functional recovery after traumatic brain injury by shifting microglia M1/M2 polarization in rats
... Stem cells from human exfoliated deciduous teeth (SHED) have been reported as an attractive source for tissue en- gineering and stem cell transplantation [1, ...
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Exosomes of stem cells from human exfoliated deciduous teeth as an anti-inflammatory agent in temporomandibular joint chondrocytes via miR-100-5p/mTOR
... mesenchymal stem cells (MSCs) for the treatment of TMJOA [7]. Stem cells from human exfoliated deciduous teeth (SHEDs) are an ideal cell source for regenerative ...
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<p>Exfoliated Human Deciduous Tooth Stem Cells Incorporating Carbonate Apatite Scaffold Enhance BMP-2, BMP-7 and Attenuate MMP-8 Expression During Initial Alveolar Bone Remodeling in Wistar Rats (<em>Rattus norvegicus</em>)</p>
... and stem cells which are then transplanted into affected areas to enhance the remodeling or regeneration of defective ...mesenchymal stem cells ...mesenchymal stem cells (GMSCs), ...
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Therapeutic applications of stem cells from human exfoliated deciduous teeth: a review
... where cells having neuron-like morphology with specific genes and proteins expression like retinal precursors, and mature photoreceptors were formed by SHED differentiation in ...formed cells remained ...
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The Effect of 1α,25(OH)2D3 on Osteogenic Differentiation of Stem Cells from Dental Pulp of Exfoliated Deciduous Teeth
... potentials. Deciduous teeth, therefore, may be an ideal resource of stem cells to induce bone ...mal stem cells have been extensively character- ized in vitro by the ex pression ...
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Immunomodulatory properties of stem cells from human exfoliated deciduous teeth
... Mesenchymal stem cell properties of ...positive cells in SHED and BMMSCs were significantly higher than that of the control SHED and BMMSCs, respectively, by ALP staining (Representative of n = 5) (A) and ...
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Immunobiology of Dental Tissue-Derived Stem Cells; As a Potentiated Candidate for Cell Therapy
... Pulp Stem Cells), SHEDs (Stem cells from Human Exfoliated Deciduous teeth), DFPCs (Dental Follicle Precursor Cells), SCAPs (Stem Cells from the ...
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