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human granulocytes

Antibacterial activity of cationic proteins from human granulocytes

Antibacterial activity of cationic proteins from human granulocytes

... determined by protein A do not seem to influence the susceptibility to cationic proteins. The properties of the Gram-negative envelope of E. coli that determine the susceptibility to the lytic action of serum do not ...

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Functional maturation of membrane potential changes and superoxide producing capacity during differentiation of human granulocytes

Functional maturation of membrane potential changes and superoxide producing capacity during differentiation of human granulocytes

... of human granulocytes were investigated in the human leukemia cell lines HL-60 and KG-1 differentiating in vitro and in human leukemic granulocytes obtained from chronic myelogenous ...

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Pyridine nucleotide dependent superoxide production by a cell free system from human granulocytes

Pyridine nucleotide dependent superoxide production by a cell free system from human granulocytes

... prepared from human granulocytes formed O2- at a rate of 18. 4 +/- 4.6 SE nmol/ml reaction mixture per donor, but not with glucose-6-phosphate, 6-phosphogluconate, glyceraldehyde- 3-phosphate, sodium ...

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Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes

Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes

... Clostridium difficile, a common enteric pathogen, mediates tissue damage and intestinal fluid secretion by release of two protein exotoxins: toxin A, an enterotoxin, and toxin B, a cytotoxin. Because toxin A elicits an ...

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Complement dependent histaminase release from human granulocytes

Complement dependent histaminase release from human granulocytes

... The role of particle-bound complement proteins in the induction of noncytotoxic enzyme release from human granulocytes was investigated with the use of sera genetically deficient in complement and highly ...

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Chemotactic factor inactivators of human granulocytes

Chemotactic factor inactivators of human granulocytes

... elastase and cathepsin G for their role as inactivators of chemotactic factors. Elastase and cathepsin G were purified from human neutrophils by Trasylol-Sepharose and CM-cellulose chromatography. Small amounts ...

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A comparison of the metabolic response to phagocytosis in human granulocytes and monocytes

A comparison of the metabolic response to phagocytosis in human granulocytes and monocytes

... Monocytes, like granulocytes, generate chemiluminescence during phagocytosis. Chemiluminescence is impaired 50-90% by superoxide dismutase, an enzyme which enhances the dismutation of superoxide to hydrogen ...

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Ultrastructural localization of cytochrome b in the membranes of resting and phagocytosing human granulocytes

Ultrastructural localization of cytochrome b in the membranes of resting and phagocytosing human granulocytes

... distillation-dried granulocytes were labeled with the anti- cytochrome b antibodies, followed by incubation with biotin-conjugated secondary antibody, and final labeling with streptavidin-conjugated colloidal ...

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Interaction of leukocyte chemotactic factors with the cell surface  I  Chemotactic factor induced changes in human granulocyte surface charge

Interaction of leukocyte chemotactic factors with the cell surface I Chemotactic factor induced changes in human granulocyte surface charge

... of human granulocytes was diminished after incubation with the chemotactic factors C5a, dialyzable transfer factor, and the enzymes kallikrein and plasminogen ...with human IgG, albumin, horeseradish ...

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Influence of recombinant bovine gamma interferon on neutrophil function

Influence of recombinant bovine gamma interferon on neutrophil function

... Immune interferon enhances functional properties of human granulocytes: role of Fc receptors and effect of lymphotoxin, tumor necrosis factor, and granulocyte-monocyte colony-stimulating[r] ...

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Seroprevalence of Antibody-Mediated, Complement-Dependent Opsonophagocytic Activity against Neisseria meningitidis Serogroup B in England

Seroprevalence of Antibody-Mediated, Complement-Dependent Opsonophagocytic Activity against Neisseria meningitidis Serogroup B in England

... within human granulocytes (differentiated HL60 cells) by flow cytometry, using IgG- depleted pooled human plasma as an exogenous source of ...

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Release of vitamin B12—binding protein by human leukocytes in vitro

Release of vitamin B12—binding protein by human leukocytes in vitro

... Human granulocytes (G) contain a vitamin B 12 -binding protein (B 12 BP). There is evidence that chronic myelogenous leukemia leukocytes (CMLL) may synthesize B 12 BP. Our prior studies suggested that ...

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Host granulomatous response in schistosomiasis mansoni  Antibody and cell mediated damage of parasite eggs in vitro

Host granulomatous response in schistosomiasis mansoni Antibody and cell mediated damage of parasite eggs in vitro

... of human granulocytes (96% neutrophils, 4% eosinophils) to eggs (cell/egg ratio 1,000:1) and heat-inactivated normal human serum reduced predicted egg 14CO2 generation by ...

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Mediators of histamine release from human platelets, lymphocytes, and granulocytes

Mediators of histamine release from human platelets, lymphocytes, and granulocytes

... lysosomal enzymes. The average distribution of enzyme activity was 11 ±2% (mean ±1 SD), 72 ±10%, and 17 ±8% for the nuclear, lysosomal, and supernatant fractions respectively. The histamine-releasing activity was equally ...

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The origin of the chemiluminescence of phagocytosing granulocytes

The origin of the chemiluminescence of phagocytosing granulocytes

... that granulocytes activated by a nonparticulate agent (F-) fail to liminesce show that light emission by the relaxation of singlet oxygen to the ground state does not contribute in a major way to the ...

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JAK2 V617F promotes venous thrombosis through β1/β2 integrin activation

JAK2 V617F promotes venous thrombosis through β1/β2 integrin activation

... mature granulocytes and monocytes are clearly involved, albeit at low ...that granulocytes and monocytes from JAK2 +/VF mice have an advantage in homing to the spleen, ...

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PC-3 prostate carcinoma cells release signal substances that influence the migratory activity of cells in the tumor's microenvironment

PC-3 prostate carcinoma cells release signal substances that influence the migratory activity of cells in the tumor's microenvironment

... SY5Y human neuroblastoma cells and with cells of the immune system on the example of neutrophil granulo- cytes and cytotoxic T lymphocytes (CTLs), especially with regard to the migratory activity of these ...

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Effect of recombinant bovine somatotropin on heamotological values in kundhi buffaloes

Effect of recombinant bovine somatotropin on heamotological values in kundhi buffaloes

... of Granulocytes (GR#), Lymphocytes (LY#), Mean corpuscular hemoglobin concentration (MCHC), Monocytes (MO#), Mean Platelet Volume (MPV), Platelets (P1t), Pct (%), Platelet distribution width (PDW), and White blood ...

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Survival of Transfused Normal Granulocytes in a Patient With Chronic Granulomatous Disease

Survival of Transfused Normal Granulocytes in a Patient With Chronic Granulomatous Disease

... concentrations of circulating total granulocytes and NBT-positive granulocytes at each sample time were calculated. The efficiency of yield of each granulocyte transfusion was calculated[r] ...

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Human granulocyte/pollen binding protein  Recognition and identification as transferrin

Human granulocyte/pollen binding protein Recognition and identification as transferrin

... binding of granulocytes to timothy grass pollen (granulocyte/pollen-binding protein [GPBP]). GPBP was purified by gel filtration, anion exchange, and affinity chromatography. Virtually all of the ...

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