Human leukocyte antigen
Investigation of Human Leukocyte Antigen (HLA) Class I and II Alleles and Hepatitis C Virus (HCV) Genotypes in Patients Infected with HCV
... Hepatitis C virus (HCV) is a major public health problem with more than 130 -180 million people infected worldwide. Several studies in different populations have reported the association of human leukocyte ...
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Expression of Human Leukocyte Antigen G is associated with Prognosis in Nasopharyngeal Carcinoma
... Human leukocyte antigen G (HLA-G) has multiple immune regulatory functions including the induction of immune tolerance in malignancies. The roles of HLA-G have not been investi- gated in ...
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Human leukocyte antigen gene polymorphisms are associated with systemic inflammation in hepatitis B virus-related hepatocellular carcinoma
... Meanwhile, the host immune response plays a key role in liver carcinogenesis and progression. The human leukocyte antigen (HLA) region, which is located on chromosome 6p21.3, is important for the ...
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Blighted Ovum: Roles of human leukocyte antigen-E and natural killer cells
... Human Leukocyte Antigen (HLA)-E is a non-classical HLA class I, which plays an important role to regulate cytokine secretion as controller of trophoblast invasion and regulate immune tolerance ...
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Functional disruption of human leukocyte antigen II in human embryonic stem cell
... Theoretically human embryonic stem cells (hESCs) have the capacity to self-renew and differentiate into all human cell ...applications. Human leukocyte antigen (HLA) II leads to CD4 + T ...
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Tri-Allelic Human Leukocyte Antigen (HLA) Protection Against Dementia
... Human Leukocyte Antigen (HLA) Class II DRB1*13:02 has recently been found to protect against dementia in Continental Western Europe. Here we extend those findings by evaluating the association ...
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The relationship between human leukocyte antigen DP/DQ gene polymorphisms and the outcomes of HCV infection in a Chinese population
... HIV: Human immunodeficiency virus; HLA: Human leukocyte antigen; HWE: Hardy-Weinberg equilibrium; LD: Linkage disequilibrium; MAF: Minor allele frequency; MHC: Major histocompatibility ...
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THE PROFILE OF HUMAN LEUKOCYTE ANTIGEN CLASS I IN PATIENTS WITH SCHIZOPHRENIA
... of Human Leukocyte Antigen (HLA) class 1 (A&B) alleles in the selected sample of schizophrenic patients in Iraqi ...One human leukocyte antigen -A gene (A*03) and two ...
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Association of human leukocyte antigen-DRB haplotype in multiple sclerosis population of Khuzestan, Iran
... The human leukocyte antigen (HLA) class-II alleles including HLA- DRB5*01, DQB1*0602, DRB1*1501, and DQA1*0102 may have remarkable effect in MS risk although it is controversial in ...
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Evolution of the levels of human leukocyte antigen G (HLA G) in Beninese infant during the first year of life in a malaria endemic area: using latent class analysis
... Background: HLA‑G, a non‑classical HLA class I antigen, is of crucial interest during pregnancy by inhibiting mater‑ nal immune response. Its role during infections is discussed, and it has been described that ...
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Persistent Antigens Hypothesis: The Human Leukocyte Antigen (HLA) Connection
... professional antigen presenting cells), providing widespread protection in the case of HLA-antigen matching; however, the absence of HLA-antigen matching in GWI may inflict widespread ...
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Resistance to anti-PD-1-based immunotherapy in basal cell carcinoma: a case report and review of the literature
... Case presentation: A 78-year-old woman was diagnosed with a metastatic non-small-cell-lung-cancer. Following the lack of response to two lines of systemic chemotherapy, she was treated with the anti-PD-1 monoclonal ...
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Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis
... above, and our results demonstrating that Actinobacteria been enriched in AS patients, we speculated that Actino- bacteria might modulate the ubiquitination of IκB-α. This in turn would allow the activation of NF-κB ...
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A Study of Human Leukocyte D Locus Related Antigens in Graves' Disease
... An association between Graves' disease and the human leukocyte antigen (HLA) system has previously been reported. The disease was more strongly associated with the HLA D locus antigen Dw3 than ...
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The role of neoantigen in immune checkpoint blockade therapy
... APC: antigen presentation cell; CTLA- 4: cytotoxic T lymphocyte-associated antigen-4; ERBB2IP: erbb2 interacting protein; HLA: human leukocyte antigen; Lama4: Laminin alpha subunit 4; ...
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The potential for immunoglobulins and host defense peptides (HDPs) to reduce the use of antibiotics in animal production
... of antigen presenting cells, such as den- dritic cells and ...of human peripheral blood monocytes to immature DCs resulted in upregulation of antigen presentation markers HLA- DR (human ...
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Can a combined screening/treatment programme prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies: study protocol for the multicentre randomised controlled OuTSMART trial
... Two types of study have linked antibodies (Ab) against human leukocyte antigen (HLAs) to immune-mediated injury and premature graft failure. Case – control studies have compared patients who have ...
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HLA C locus alleles may modulate the clinical expression of psoriatic arthritis
... The aim of the present study was to evaluate the relative contribution of human leukocyte antigen (HLA)-C locus alleles in determining the risk and the clinical expression of psoriatic arthritis ...
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Clinical review: flow cytometry perspectives in the ICU from diagnosis of infection to monitoring of injury induced immune dysfunctions
... studying human clinical samples, particularly in infl ammatory Figure ...monocyte human leukocyte antigen-DR expression (mHLA-DR) measurements, the gated region includes all monocytes and the ...
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Comparison of efficacy and safety of epalrestat with methylcobalamin in patients with diabetic neuropathy
... HbA1C Glycosylated Hemoglobin HDL High Density Lipoprotein HHS HLA-DR Hyperosmolar hyperglycaemicnonketotic coma Human Leukocyte Antigen – antigen D Related HNF Hepatocyte nuclear transc[r] ...
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