human lymphatic endothelial cells
Andes Virus Infection of Lymphatic Endothelial Cells Causes Giant Cell and Enhanced Permeability Responses That Are Rapamycin and Vascular Endothelial Growth Factor C Sensitive
... Human lymphatic endothelial cells from HPS patients contain hantavirus antigens (86), suggesting that in vitro LEC responses observed here may also contribute to HPS in ...hantavirus-infected ...
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Macrophage derived interleukin 1beta promotes human breast cancer cell migration and lymphatic adhesion in vitro
... confluent endothelial mon- olayer that remained unstimulated, or was stimulated with IL-1β for 24 ...tumour cells were counted using a fluorescence microscope ...of cells adhered relative to ...the ...
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H , N and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice
... Three highly related GTPases, H-, N- and Kras, encoded by the three mammalian Ras genes, have been thought to play pivotal roles in the intracellular signalling pathways that regulate cell proliferation, survival and ...
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Lymphatic mimicry in maternal endothelial cells promotes placental spiral artery remodeling
... uNK cells contribute to SA SMC regulation during remodeling, and that uNK cells promote downstream endothelial ERK signaling at the time in which VEGFR3 is initially expressed (Figure 2, C and D), we ...
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Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis
... myelocytic cells in the localization of ...myelocytic cells, because the hLEC cytosol could represent a more permissive environment for ...primary human macrophages and (b) ...resting cells, ...
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Hypoxia Induces Permeability and Giant Cell Responses of Andes Virus-Infected Pulmonary Endothelial Cells by Activating the mTOR-S6K Signaling Pathway
... infects human pulmo- nary microvascular and lymphatic endothelial cells (MECs and LECs, respectively) and nonlytically enhances the permeability of interendothelial cell adherence junctions in ...
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Ets-1 Is Required for the Activation of VEGFR3 during Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells
... to lymphatic endothelial cell ...lial cells induces reprogramming to lymphatic endothelium and the expression of VEGFR3 (11, 12, ...other lymphatic-specific ...another lymphatic ...
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Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation
... invasive human cytotrophoblasts in vivo by transplanting placental villi to the fifth mammary fat pads or beneath the kidney capsules of Scid ...the cells’ interactions with resident murine blood vessels, ...
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Diphtheria toxin–mediated ablation of lymphatic endothelial cells results in progressive lymphedema
... Over the last century, a considerable effort has been expended to develop animal models of lymph- edema. Although a variety of models that display some characteristics of clinical lymphedema have been developed, these ...
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Original Article Lymphangigenesis in human epithelial ovarian cancer is related to the formation of ascites
... for lymphatic endothelial ...defined lymphatic marker in archi- val human tissue sections, thereby enabling more widespread studies of tumor lymphangio- genesis in human cancers ...of ...
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Lymphatic endothelial cells promote productive and latent HIV infection in resting CD4+ T cells
... from human umbilical cords ...the lymphatic vessels in the lymph nodes are microvascular ...single human organ ...cer cells [35], respond more strongly to certain growth factors [36], and ...
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Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells
... of net bacterial growth. We, therefore, quantified the total GFP signal per hLEC cell (GFP/cell) from 2 to 72 hpi with each Mtb strain (Fig. 5a). Measurements of the colony-forming units were not used because of the in- ...
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Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk
... The endothelial cells of the vertebrate lymphatic system assemble into complex networks, but local cues that guide the migration of this distinct set of cells are currently ...for ...
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Intercellular adhesion molecule 1 and CD36 synergize to mediate adherence of Plasmodium falciparum infected erythrocytes to cultured human microvascular endothelial cells
... CHO cells (9, 10), amelanotic melanoma cells (7, 8, 25, 26), and human umbilical endothelial cells (HU- VEC) (10, ...fashion. Human dermal microvascular endothelial ...
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Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL
... , there was no major increase in mRNA synthesis in the LEC subsets isolated from the mutant mice (panel C in S5 Fig). However, because the proportion of MAdCAM-1 + LECs greatly aug- mented in the transgenic mice (panel C ...
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Joerg, Anita (2004): Auswirkungen der maternalen HIV-1-Infektion auf die Genexpression endothelialer Vorläuferzellen und differenzierter Endothelzellen nicht-infizierter Kinder. Dissertation, LMU München: Fakultät für Biologie
... HUVEC: Endothelzellen aus der Nabelschnurvene ( Human Umbilical Vein Endothelial Cells ) HUAEC: Endothelzellen aus der Nabelschnurarterie ( Human Umbilical Artery Endothelial Cells [r] ...
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Correlation between lymphatic endothelial markers and lymph node status or N staging of colorectal cancer
... melanogaster; it has the functions of regulating cell mi- tosis and inducing the differentiation of lymphatic endo- thelial cells [22]. Parr et al. [23] found that colorectal cancer tissues had a higher ...
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Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation
... We next tested whether DCs express VEGFR3, the receptor for VEGF-C. CD11c+BMDCs significantly upregulated VEGFR3, and to a lesser extent VEGFR2 and VEGFR1, in response to IFN-γ or TPA stimulation (Figure 3A). However, ...
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Everolimus for Primary Intestinal Lymphangiectasia With Protein-Losing Enteropathy
... To the best of our knowledge, this is the first report of everolimus use in a patient with PIL. The clinical response to mTOR inhibitors such as sirolimus and everolimus may be related to inhibition of lymphatic ...
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Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions
... and lymphatic endothelial cell markers PECAM1, Prox1 and Nrp2 ...dermal lymphatic vessels were abnormally dilated in Rasip1 conditional null embryos ...filled lymphatic vessels in Rasip1 ...
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