human mammary epithelial cell
KISS1R Induces Human Mammary Epithelial Cell Invasiveness and Promotes Breast Cancer Cell Migration and Invasion via IQGAP1
... non-malignant human mammary epithelial MCF10A cells and moderately invasive SKBR3 stably expressing either FLAG-KISS1R or pFLAG-A1 (vector control), to form organotypic invasive structures in 3D ...
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Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis
... immortalized human mammary epithelial cell line, ER-PR-Her2+ and ER-PR-Her2- breast cancer cell lines were ...the cell cycle, DNA replication, mitosis, apoptosis, and DNA ...all ...
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Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation
... cancer cell line in ...cancer cell proliferation compared to non-cancer cells ...cancer cell growth and survival by enhancing metabolic stress, particularly by down-regulating total glycolytic ...
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LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling
... immortalized human mammary epithelial cell line MCF10A increased expression of LOXL2 interferes with normal acini development by repressing apoptosis, prolonging proliferation, and abro- ...
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Stem Cell Research: A Novel Boulevard towards Improved Bovine Mastitis Management
... specific cell types (as per need), and subsequently these specific stem cells can be used to treat specific diseases or re- pair tissue injury, such as post mastitis mammary tissue ...stem cell is ...
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Proteomic analysis of ErbB-2 overexpression in human mammary luminal epithelial cell lines
... As mentioned previously, 2DE-based proteomic studies are somewhat limited since only a fraction o f the proteome can be visualised on a 2DE gel (as reported by Corthals et al. 2000). It is estimated that o f the tens o f ...
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Transglycosylation products generated by Talaromyces amestolkiae GH3 β-glucosidases: effect of hydroxytyrosol, vanillin and its glucosides on breast cancer cells
... The human breast adenocarcinoma cell line MCF-7 was obtained from the American Type Culture Col- lection (ATCC) and maintained in Eagle’s Minimum Essential Medium (MEM) (Gibco by Thermo Fisher Scientific) ...
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Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF) β and Neu pathway signaling studies: identification of a novel model for TGF β induced epithelial to mesenchymal transition
... Mouse monoclonal β-catenin and N-cadherin antibodies were purchased from Transduction Laboratories (Missis- sauga, ON, Canada), a monoclonal E-cadherin antibody (anti-uvomorulin clone Decma-1) was purchased from Sigma ...
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The WNT controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage
... stem cell self-renewal and quiescence, and promotes basal epithelial characteristics by regulating transcription of genes involved in cell proliferation, adhesion and the basal cytoskeleton, ...
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Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer
... normal human breast is composed of two cell layers, an inner luminal cell population and a distinct outer cell layer, juxtaposed to the basement membrane, termed the ‘basal’ layer ...the ...
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Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells
... several human cancer cell lines, MCF‑7, HepG2, HepG2/ ADM, HeLa, and PC3, and normal human mammary epithelial cells MCF10A were investigated by colony formation and MTT ...The ...
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Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells
... the epithelial tumor, as well as in the tumor itself, we hypothesize that c-myc expression plays an important role in mammary cell ...the epithelial tumors, as demonstrated by absence of ...
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CCAAT/Enhancer Binding Protein-delta (C/EBP-delta) regulates cell growth, migration and differentiation
... and human cells in response to growth arrest conditions ...cancer cell lines ...HC11 cell lines approach contact mediated growth inhibition (48-72 hours), pSTAT3 and C/EBPδ protein levels increase ...
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Uptake of DNA by cancer cells without a transfection reagent
... immortalized human liver cells, which are nontumo- rigenic and AFP expression negative, and were cultured in BEBM medium (Lonza/Clonetics) supplemented with various growth ...cancer cell lines Huh7 and ...
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PER2 regulation of mammary gland development
... MCF10A cell line was chosen because it is characterized as a normal breast epithelial cell line that is under circadian control (Xiang et ...mouse mammary glands (Fig. 2F). Consistent with the ...
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Cancer stem cells and oral cancer: insights into molecular mechanisms and therapeutic approaches
... From among the above pathways, researchers largely confirmed contribution Bmi1 and Notch signaling in oral cancer stemness. Activating the Notch1 signaling pathway is necessary to maintain cancer stem cells, and demands ...
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Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells
... Drug resistance is the major reason for treatment failure in most human cancers [75-78]. While few cancers eventually display an inherent resistance to chemotherapy, the majority of cancers acquire multi-drug ...
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Innate defense capability of challenged primary bovine mammary epithelial cells after an induced negative energy balance in vivo
... The accomplished PCAs on ∆Cq-level according to the functional gene groups showed a clear sepa- ration of E. coli infection compared to S. aureus and control cells (Figure 2). High variation within the data set is also ...
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Intraepithelial neutrophils in mammary, urinary and gall bladder infections
... the mammary alveoli, phago- cytosis of apoptotic neutrophils by macrophage may not be the only or most important mechanism of neutrophil safe disposal and homeostasis of ...the mammary gland macrophage ...
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CCL2 driven inflammation increases mammary gland stromal density and cancer susceptibility in a transgenic mouse model
... apoptotic epithelial cells were captured and collected using FV10i Confocal Microscope (Olympus, USA) with laser-power and photomultiplier settings kept constant for all experiments, and images were captured at × ...
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