Human melanoma
Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging.
... malignant melanoma in the last few years, with these drugs now commonly used in ...clinic. Melanoma cells treated using these agents are known to exhibit increased levels of melanin pigment and tyrosinase ...
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Inhibition of Pannexin 1 reduces tumorigenic properties of human melanoma
... of human melanoma cell lines may occur from direct modulation of actin by ...BL6 melanoma cells, and have been shown to be characteristic of a more melanocytic-like phenotype [38, ...and ...
103
Measles virus causes immunogenic cell death in human melanoma
... against human melanoma cell ...four human melanoma cell lines (Mel888, Mel624, MeWo, ...B; Melanoma cells were infected with GFP-expressing MV at a range of ...replication. ...
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Interleukin-32 induces migration of human melanoma cells through downregulation of E-cadherin
... The human melanoma cell lines G361, A375, SK-MEL-5, SK-MEL-28, Hs 294T and WM-266-4 were purchased from ATCC or KCLB and cultured in Dulbecco’s Modified Eagle media (DMEM) with 10% fetal bovine serum ...
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Melanotropin receptors demonstrated in situ in human melanoma
... cultured human melanoma cell lines are responsive to melanotropins (melanocyte-stimulating hormones [MSH]), the prevalence and tissue distribution of MSH receptors in melanoma are ...In ...
9
Efficient tumour formation by single human melanoma cells
... to human CD45 (HI30-APC, BD Biosciences), human CD31 (WM59-APC, eBiosciences) and Glycophorin A (HIR2-APC, Biolegend) (for tumours obtained directly from patients) or mouse CD45 (30-F11-APC, eBiosciences), ...
7
Natural Compounds As Selective Inducers of Apoptosis In Human Melanoma Cells
... A375 human melanoma cells and incubated for 1 hour separately with caspase-3 fluorogenic substrate (DEVD-AFC) in DEVD buffer, caspase-8 fluorogenic substrate (IETD-AFC) in IETD or caspase-9 fluorogenic ...
182
Cell proliferation in human melanoma
... The cytokinetics of subcutaneous metastases in five patients with melanoma was studied. Multiple simultaneous biopsies following pulse labeling with tritiated thymidine were performed in one patient. There was ...
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Acridone and Its Analogues Emphasizing As Anticancer Agents
... anti-cancer activity was performed by using cancer cell lines human lung carcinoma cell line, COR-1. L23, human breast adenocarcinoma cell line MCF7, the human melanoma cell line, C32 a[r] ...
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The Emerging Role of the Thrombin Receptor (PAR-1) in Melanoma Metastasis - a Possible Therapeutic Target
... in melanoma progression is essential, as current therapies for metastatic melanoma are not ...stage melanoma patients also have limited response rate of less than 20% [9-12] ...for human ...
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Overview of advances in vasculogenic mimicry – a potential target for tumor therapy
... both human melanoma cell lines and human endothelial cell lines in vitro; marked inhibition on the vascular cord and tube formation were observed in endothelial cells as compared to melanoma ...
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Orally administered endoxifen inhibits tumor growth in melanoma-bearing mice
... The effect of endoxifen in human melanoma cell lines was evaluated using the sulfor- hodamine B (SRB) assay in the single-dose (10 μM) format from the National Cancer Institute. Briefly, approximately 5 × ...
7
Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4Rα overexpressed melanoma models
... of melanoma cell ...in human melanoma tissues in a cancer stage dependent ...in human tumor tissue is increased in gastric [53], laryngeal [54] cancer cells as well as melanoma ...
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Antisense oligonucleotide–mediated MDM4 exon 6 skipping impairs tumor growth
... cutaneous melanoma (SKCM) samples (from The Cancer Genome Atlas [TCGA]) provides evidence that the full-length, protein-coding transcript is produced in the major- ity of these ...TCGA melanoma cohort (for ...
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Abstract
... of human melanoma (BM) cells and murine normal fibroblasts (3T3−Balb) in the two higher concentrations (400 and 40 ...in human blood (4 µg/ml) slightly decreased the proliferation of human ...
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Myxoma Virus Leukemia-Associated Protein Is Responsible for Major Histocompatibility Complex Class I and Fas-CD95 Down-Regulation and Defines Scrapins, a New Group of Surface Cellular Receptor Abductor Proteins
... MV-infected human melanoma cells, it should be noted that the melanoma cell lines used do not express HLA-C and that we did not monitor for HLA specificities other than HLA-A, -B, and ...the ...
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Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype
... from melanoma result from ...metastatic human cell lines in vitro and in vivo, which suggested that it may be a metastasis inhibi- ...Metastatic human melanoma cells were transfected with ...
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The combination of MLN2238 (ixazomib) with interferon-alpha results in enhanced cell death in melanoma
... wild-type human melanoma tumor ...mutant melanoma tumor cells; however, this was not seen in BRAF wild-type ...of human melanoma, combination treatment with IFN-α-2b and ixazomib ...
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In Vitro Determination of Biological and Anabolic Functions of Weak Androgen Dehydroepiandrosterone (DHEA) Using a Variety of Cell Lines
... and human melanoma cancer cell lines (target cancer) were ...As human gastric cancer (NUGC3) cell was earlier used to study the effect of Orlistat on cell growth and was found to inhibit gastric ...
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Lunasin is a novel therapeutic agent for targeting melanoma cancer stem cells
... with human melanoma cell ...SKMEL-28 melanoma cells exhibited a significant dose-dependent decrease in colony formation in soft agar assays upon exposure to Lunasin (Figure 1D and ...of ...
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