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Human Metapneumovirus

New Approaches for Immunization and Therapy against Human Metapneumovirus

New Approaches for Immunization and Therapy against Human Metapneumovirus

... TO HUMAN METAPNEUMOVIRUS In RSV, the nonstructural proteins NS-1 and NS-2 help the virus evade innate immunity via inhibition of type 1 interferon signal- ing ...

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Recovery of Avian Metapneumovirus Subgroup C from cDNA: Cross-Recognition of Avian and Human Metapneumovirus Support Proteins

Recovery of Avian Metapneumovirus Subgroup C from cDNA: Cross-Recognition of Avian and Human Metapneumovirus Support Proteins

... Avian metapneumovirus (AMPV), previously known as tur- key rhinotracheitis virus or avian pneumovirus, causes an acute respiratory disease in turkeys and is also associated with “swol- len head syndrome” in ...

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Prevalence, clinical outcomes and rainfall association of acute respiratory infection by human metapneumovirus in children in Bogotá, Colombia

Prevalence, clinical outcomes and rainfall association of acute respiratory infection by human metapneumovirus in children in Bogotá, Colombia

... Hoogen, human metapneumovirus (HMPV), belonging to the Paramyxo- viridae family, has circulated for more than five decades [3], but its importance as an etiologic agent of upper and lower ARI, with the ...

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Characterization of Human Metapneumovirus Infections in Israel

Characterization of Human Metapneumovirus Infections in Israel

... Human metapneumovirus (hMPV), a newly discovered vi- rus, is an enveloped single-stranded negative-sense RNA virus (41). hMPV has been classified as a member of the Paramyxo- viridae family and has been ...

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Relevance of human metapneumovirus in exacerbations of COPD

Relevance of human metapneumovirus in exacerbations of COPD

... 3. Human metapneumovirus (hMPV) is a recently discov- ered respiratory virus first isolated from a dutch child with lower respiratory tract infection ...

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Cytokine Profiles in the Respiratory Tract During Primary Infection With Human Metapneumovirus, Respiratory Syncytial Virus, or Influenza Virus in Infants

Cytokine Profiles in the Respiratory Tract During Primary Infection With Human Metapneumovirus, Respiratory Syncytial Virus, or Influenza Virus in Infants

... METHODS. A prospective study of infants who were seeking medical help for acute upper and/or lower respiratory tract infection symptoms for the first time and were found to be infected with influenza, human ...

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Isolation and Characterization of Monoclonal Antibodies Which Neutralize Human Metapneumovirus In Vitro and In Vivo

Isolation and Characterization of Monoclonal Antibodies Which Neutralize Human Metapneumovirus In Vitro and In Vivo

... Human metapneumovirus (hMPV) is a recently described member of the Paramyxoviridae family/Pneumo- virinae subfamily and shares many common features with respiratory syncytial virus (RSV), another member of ...

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Human Metapneumovirus Infection in Japanese Children

Human Metapneumovirus Infection in Japanese Children

... Human metapneumovirus (hMPV) was recently isolated in The Netherlands and found to be a new paramyxovirus belong- ing to the genus Metapneumovirus of the subfamily Pneumo- virinae of the family ...

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Human Metapneumovirus Small Hydrophobic Protein Inhibits NF-κB Transcriptional Activity

Human Metapneumovirus Small Hydrophobic Protein Inhibits NF-κB Transcriptional Activity

... Human metapneumovirus, a leading cause of respiratory tract infections in infants, encodes a small hydrophobic (SH) protein of unknown ...recombinant human metapneumovirus lacking SH ...

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Structural Insights into the Human Metapneumovirus Glycoprotein Ectodomain

Structural Insights into the Human Metapneumovirus Glycoprotein Ectodomain

... Human metapneumovirus is a major cause of respiratory tract infections worldwide. Previous reports have shown that the viral attachment glycoprotein (G) modulates innate and adaptive immune responses, ...

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siRNA against the G gene of human metapneumovirus

siRNA against the G gene of human metapneumovirus

... Human metapneumovirus (hMPV) is a member of the Pneumoviridae subfamily of the Paramyxoviridae [1]. hMPV infects half of all infants under the age of 1 year and almost all children have been infected by the ...

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Human metapneumovirus in the preterm neonate: current perspectives

Human metapneumovirus in the preterm neonate: current perspectives

... morbidity. Human metapneumovirus (HMPV) is a paramyxovirus discovered in 2001 that is related to respiratory syncytial ...disease, human metapneumovirus, bronchiolitis, ...

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Community Epidemiology of Human Metapneumovirus, Human Coronavirus NL63, and Other Respiratory Viruses in Healthy Preschool-Aged Children Using Parent-Collected Specimens

Community Epidemiology of Human Metapneumovirus, Human Coronavirus NL63, and Other Respiratory Viruses in Healthy Preschool-Aged Children Using Parent-Collected Specimens

... for human metapneumovirus (6.1%) and 18 for human coronavirus NL63 ...tested, human metapneumovirus and human coronavirus NL63 were most strongly linked to child care attendance, ...

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Human Metapneumovirus Infection in the Canadian Population

Human Metapneumovirus Infection in the Canadian Population

... paramyxovirus, human metapneumovirus (hMPV), that was tentatively as- signed to the Metapneumovirus genus of the Pneumovirinae subfamily was identified by Van den Hoogen et ...

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Genetic Variability of the G Glycoprotein Gene of Human Metapneumovirus

Genetic Variability of the G Glycoprotein Gene of Human Metapneumovirus

... Human metapneumovirus (hMPV) has been associated with respiratory illnesses like those caused by human respiratory syncytial virus (HRSV) infection. Similar to other pneumoviruses, genetic diversity ...

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Outbreak of Human Metapneumovirus in Ibaraki, Japan and Its Descriptive Epidemiology

Outbreak of Human Metapneumovirus in Ibaraki, Japan and Its Descriptive Epidemiology

... of human metapneumovirus (HMPV), a virus usually causing res- piratory symptoms such as pneumonia or bronchitis among children [1] [2] [3], was reported at a facility for elderly people in Japan in 2013 ...

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Status Epilepticus: A Possible Association With Human Metapneumovirus Infection

Status Epilepticus: A Possible Association With Human Metapneumovirus Infection

... 1. Edwards KM, Zhu Y, Grif fi n MR, et al; New Vaccine Surveillance Network. Burden of human metapneumovirus infection in young children. N Engl J Med. 2013;368(7):633 – 643 2. van den Hoogen BG, de Jong JC, ...

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Human metapneumovirus infections on the ICU: a report of three cases

Human metapneumovirus infections on the ICU: a report of three cases

... Although human metapneumovirus (hMPV) is primarily known as a causative agent of respiratory tract infections in children, the virus also can cause respiratory infections in ...

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Molecular Assays for Detection of Human Metapneumovirus

Molecular Assays for Detection of Human Metapneumovirus

... pathogen human metapneumovirus (hMPV) has highlighted a deficiency in current diagnostic techniques for viral agents associated with acute lower respiratory tract ...

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Large scale seroprevalence analysis of human metapneumovirus and human respiratory syncytial virus infections in Beijing, China

Large scale seroprevalence analysis of human metapneumovirus and human respiratory syncytial virus infections in Beijing, China

... Background: Human metapneumovirus (hMPV), a recently identified virus, causes acute respiratory tract infections (ARTIs) in infants and ...the human serum antibody against the N protein of ...

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