Human-Monocytes
Infection of Primary Human Monocytes by Epstein-Barr Virus
... with human monocytes and was able to modulate cytokine synthesis (17, ...infected monocytes which might have accounted for the pre- viously reported TNF-␣ suppression ...targeting ...
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Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon gamma by natural killer cells in vitro
... recombinant human IL-15 uses the IL-2 receptor to activate human NK cells and can synergize with recombinant human IL-12 to stimulate NK cell production of IFN-gamma in ...that human ...
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Binding of fibrinogen to human monocytes
... with monocytes was ...of human monocytes bind 125I- fibrinogen with two different affinities in a specific and Ca2+-dependent reaction with saturation at ...on monocytes induces the ...
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Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia
... of monocytes can be adapted to variable oxygen ...of monocytes incubated under hypoxia ...in monocytes to be sig- nificantly induced under ...in human monocytes and human MDMs, ...
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Constitutive expression of p50 homodimer in freshly isolated human monocytes decreases with in vitro and in vivo differentiation: a possible mechanism influencing human immunodeficiency virus replication in monocytes and mature macrophages.
... NF- k B is a transcription factor (2) which strongly activates transcription of human immunodeficiency virus (HIV) provi- rus in T cells (22) and monocytic cells (1, 10, 33). The NF- k B/ Rel family of proteins is ...
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Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability.
... Non-classical monocytes release significantly less mature IL-1β upon LPS/LPS+BzATP stimu- ...primary human monocytes from the peripheral blood of healthy donors by fluores- cence-activated cell ...
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VLA 4 integrin can mediate CD11/CD18 independent transendothelial migration of human monocytes
... of human monocytes across unactivated and activated human umbilical vein endothelium (HUVE) in response to chemotactic factors was studied, and the adhesion molecules involved were ...blood ...
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Phenotypic characteristics of human monocytes undergoing transendothelial migration
... As described previously [19,20], we found that pretreat- ment of the endothelium with certain chemokines or cytokines enhanced transendothelial migration. The most striking phenotypic changes were seen for ICAM-1 ...
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Synthesis and expression of the fibroblast fibronectin receptor in human monocytes
... Human monocytes adhere to fibronectin, but the receptor (or receptors) mediating this interaction has not been clearly ...receptor, human monocytes were obtained by counter-current elutriation ...
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Postentry Restriction to Human Immunodeficiency Virus-Based Vector Transduction in Human Monocytes
... transduce human monocytes and ...on human 293T ...isolated monocytes were refractory to transduction by HIV vectors pseudotyped with either VSV-G or MLV-A ...in human serum the MDMs ...
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Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy
... in human B cells (Figure ...by human pDCs upon TLR9 activation (Figure ...by human monocytes (Figure 2E) or acti- vation of the JAK–STAT pathway stimulated with either IL-2 or IFNγ (Figure ...
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The fungicidal mechanisms of human monocytes I Evidence for myeloperoxidase linked and myeloperoxidase independent candidacidal mechanisms
... by monocytes from a patient with hereditary myeloperoxidase deficiency, was selected to examine the myeloperoxidase- independent fungicidal mechanisms of ...monocytes. Monocytes were obtained from ...
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Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator–activated receptor γ
... Human monocytes were isolated as described earlier ...adhering monocytes were harvested by brief trypsinization. The purity of monocytes was greater than 85% as estimated by flow cytometry ...
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Evidence for hydroxyl radical generation by human Monocytes
... of human monocytes were demonstrated to generate hydroxyl radical or a similar agent during phagocytosis of zymosan ...generation. Monocytes from a patient with chronic granulomatous disease failed ...
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Volumetric and functional heterogeneity of human monocytes
... zymosan-activated human serum by total monocytes, M1 + M2 monocytes, and M3 monocytes was determined by the agarose plate ...M3 monocytes were 10-fold more responsive than M1 + M2 ...
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Differential expression of CD148 on leukocyte subsets in inflammatory arthritis
... In human RA CD148 is upregulated in both T cells and macrophages and in addition TNFa, a cytokine enriched in RA synovial fluid, can increase the tyrosine phospha- tase activity of ...
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Cell Cell Interaction in Erythropoiesis: ROLE OF HUMAN MONOCYTES
... of monocytes on peripheral blood BFU-E proliferation in response to erythropoietin was investigated in the plasma clot culture ...normal human donors were separated into four ...(20-30% monocytes; ...
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Directional budding of human immunodeficiency virus from monocytes.
... are monocytes/macrophages rather than lymphocytes, because vi- ruses isolated from patients infected through sexual contact and in the acute phase of infection are primarily macrophage tropic (52) and ...
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Activated platelets signal chemokine synthesis by human monocytes
... to monocytes and induce MCP-1 se- ...mixing monocytes with platelets that were activated by thrombin re- sulted in adhesion between the two ...the monocytes, and platelet–mono- cyte rosettes were ...
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A comparison of the metabolic response to phagocytosis in human granulocytes and monocytes
... Monocytes, like granulocytes, generate chemiluminescence during phagocytosis. Chemiluminescence is impaired 50-90% by superoxide dismutase, an enzyme which enhances the dismutation of superoxide to hydrogen ...
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