Human monocytes/macrophages
Characterization of substance P binding to human monocytes/macrophages.
... We determined that 1251-SP bound to a specific receptor on human monocytes/macrophages and that this binding was detectable as early as 6 h and was maintained throughout 6 to 8 weeks in [r] ...
6
Interaction of human monocytes, macrophages, and polymorphonuclear leukocytes with zymosan in vitro Role of type 3 complement receptors and macrophage derived complement
... that macrophages themselves secrete complement-alternative pathway components able to opsonize zymosan locally (Ezekowitz et ...adherent human monocytes in the absence of ...
10
Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus
... and monocytes. Here, we demonstrate that blood-derived human monocytes are permissive to VZV replication in ...VZV-infected monocytes exhibited each temporal class of VZV gene expression, as ...
17
Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia
... of human monocytes into macrophages, the more potent and possibly more robust HIF-1 system is ...the monocytes with PMA (which although non-physiological is usually applied to differ- entiate ...
12
Identification of intracellular factor XIII in human monocytes and macrophages
... The results presented thus indicate that human monocytes and macrophages contain a cytoplasmic protein with potential transglutaminase activity, which is identical to the A protein of pl[r] ...
8
Colorectal cancer derived microvesicles modulate differentiation of human monocytes to macrophages
... of human monocytes to ...[20]. Monocytes cultured alone (without TMVs) were used as a control (equivalent to M0 macrophages) [21] and defined as control ...
15
Activation of Terminally Differentiated Human Monocytes/Macrophages by Dengue Virus: Productive Infection, Hierarchical Production of Innate Cytokines and Chemokines, and the Synergistic Effect of Lipopolysaccharide
... blood monocytes (MO) and tissue macrophages (M ...primary human MO/M regardless of the stage of cell ...differentiated human MO/M was enhanced and prolonged in the presence of ...
11
CYCLIC NUCLEOTIDES CONTROL DIFFERENTIATION OF HUMAN MONOCYTES INTO EITHER HIGHLY ACCESSORY CELLS OR MACROPHAGES
... Phosphory lated adenine nucleotides such as AMP, ADP and ATP are converted into adenosine by a cell surface ATPase found on monocytes. After being dephosphorylated, adenosine exerts its effect via the adenosine ...
10
Twin studies demonstrate a host cell genetic effect on productive human immunodeficiency virus infection of human monocytes and macrophages in vitro.
... in monocytes and macrophages (8, 17), this evidence in twins is the first to demonstrate a clear effect of host cell ...donor monocytes/macrophages reached a maximum of 400-fold but HIV ...
12
Cytomegalovirus induction of tumor necrosis factor alpha by human monocytes and mucosal macrophages
... inclusions, were positively associated with CMV, but not HIV-1, within the mucosa. In in vitro experiments, a patient-derived isolate of CMV, but not HIV-1Ba-L, induced human monocytes to express TNF-alpha ...
8
A lymphokine regulates expression of alpha 1 proteinase inhibitor in human monocytes and macrophages
... individuals. In this study, expression of alpha 1 PI by blood monocytes, bronchoalveolar, and breast milk macrophages decreased during 1 wk in culture whereas expression of other secreted proteins ...
8
A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages
... LPS-stimulated monocytes and macrophages through its reduction in NF- κB-mediated TNFα ...by monocytes and macrophages causes various effects involved in destabilising the atherosclerotic ...
10
Effects of PM10 in human peripheral blood monocytes and J774 macrophages
... The present study clearly shows that the same dose of PM 10 (10 µg/ml) that induces calcium elevation also stim- ulates significant increases in both TNF-α protein release and IL-1α mRNA production by macrophages. ...
12
Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production
... activate macrophages, but rhinovirus replication in macrophages has not been ...in human macrophages causes activation and nuclear translocation of NF- B, leading to TNF- ␣ ...Using ...
11
Angiocentric CD3+ T-Cell Infiltrates in Human Immunodeficiency Virus Type 1-Associated Central Nervous System Disease in Children
... in human brain-derived endothelial cells infected with HIV-1 in vitro ...cells, macrophages, and oligodendroglia and HLA class II ex- pression on macrophages, oligodendroglia, and occasional en- ...
10
Macrophage/monocyte receptor for nonenzymatically glycosylated protein is upregulated by cachectin/tumor necrosis factor
... peritoneal macrophages and human blood monocytes in vitro, and that cachectin/TNF enhanced the rate of disappearance of AGE- modified red blood cells in ...
9
Macrophage adaptation in airway inflammatory resolution
... regulated macrophages so that they are more responsive and able to sense more readily a pathogenic micro-organism. However, this assumes that the defect or alteration is within the macrophage, but we believe the ...
6
Dengue Virus Nonstructural Protein NS5 Induces Interleukin-8 Transcription and Secretion
... Elevated circulating levels of chemokines have been reported in patients with dengue fever and are proposed to contribute to the pathogenesis of dengue disease. To establish in vitro models for chemokine induction by ...
9
Resistin directly inhibits bacterial killing in neutrophils
... We tested this hypothesis by exposing innate immune cells to two common and often deadly nosocomial agents whose pathogenesis varies significantly: Pseudomonas aerugi- nosa, a Gram-negative organism, and Staphylococcus ...
12
A folate receptor beta specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody dependent cell mediated cytotoxicity
... activated macrophages that accumulate at sites of inflammation and in some tumors ...Resting macrophages, which are abundant in normal tissues and participate in homeostasis, have not been found to express ...
12