human myometrium
Ghrelin in the human myometrium
... In human endothelial cells it inhibits NF-κB activation in vitro and endotoxin-induced cytokine production in vivo ...in human T cells while it's knockdown activates IκB in these cells, suggesting ghrelin ...
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The onset of labor alters corticotropin releasing hormone type 1 receptor variant expression in human myometrium : putative role of interleukin 1ß
... primary human myometrial cells were used, obtained from term hu- man quiescent myometrial ...in human myometrium and other feto-maternal tissues (27) and in- creased p65 (RelA):p50 heterodimer DNA ...
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Nuclear factor of activated T-cell isoform expression and regulation in human myometrium
... the myometrium must grow in size to accommodate the fetus and amniotic fluid, resulting in a 20-fold expansion in size and at term must become contractile in preparation for labour ...in human pregnancy ...
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Study the effect of Fasudil on the contractility of isolated nonpregnant human myometrium and to analyse the possible mechanism involved
... relax human myometrium considering the fact that Fasudil is capable of relaxing the blood vessels which are structurally and functionally similar to other smooth muscles in the ...rat myometrium at ...
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Analysis of Maxi-K alpha subunit splice variants in human myometrium
... during human pregnancy and ...in human myometrium, and also highlights alternative exon splicing as a potentially important control mechanism by which myometrial Maxi-K channels may be modulated to ...
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Characterization of the tissue level Ca2+signals in spontaneously contracting human myometrium
... dissociated human myometrial cells rarely show spontaneous activity suggesting that myometrial autorhythmicity may represent an emergent property of the cellular network ...of human myometrium is ...
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Single cell mechanics and calcium signalling in organotypic slices of human myometrium
... been subjected to enzymatic treatment for cell isolation or cell culture conditions. However, the spatio- temporal resolution of such recording is limited due to the motion artifacts occurring in contracting tissue. Here ...
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Study of the effect of Tadalafil on the Contractility of Isolated Non- Pregnant Human Myometrium
... contractility of myometrial tissue. The relaxant effect of PDE5 inhibitor was not reversed both by the specific adenylate cyclase inhibitor or specific guanylate cyclase inhibitor. In fact an increase in relaxant effect ...
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Expression of RHOGTPase regulators in human myometrium
... in human myo- metrium at term labour, at labour and in the non- pregnant state and also in human myometrial smooth muscle ...4) human myometrium, and HeLa (H) ...
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The effect of trichostatin-A and tumor necrosis factor on expression of splice variants of the MaxiK and L-type channels in human myometrium
... of human parturition is associated with up-regulation of pro-inflammatory cytokines including tumor necrosis factor (TNF) as well as changes in ion flux, principally Ca 2+ and K + , across the myometrial myocytes ...
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Prostacyclin primes pregnant human myometrium for an enhanced contractile response in parturition
... in human myometrial tissue. (A and B) Human myometrial tissue strips in organ culture were pretreated with 25 nmol/l iloprost for (A) 48 h or (B) 6 ...from human myometrial tissue in organ culture ...
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Poor spontaneous and oxytocin stimulated contractility in human myometrium from postdates pregnancies
... labouring myometrium, unlike non-labouring, the duration of the contrac- tions, as well as area under the curve, was significantly ...postdates myometrium to achieve spontaneous contractile activity in ...
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Characterization of the molecular and electrophysiological properties of the T type calcium channel in human myometrium
... Panel B HVA/LVA expressing cells mean± SE n=12 per point current density vs step voltage from a holding potential of -50mV closed circle and 80mV closed square.. Mean current density at [r] ...
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Corticotropin releasing hormone interacts with interleukin 1 to regulate prostaglandin H synthase 2 expression in human myometrium during pregnancy and labor
... comparing relative expression in real-time PCR. Results are expressed as the group’s mean ⫾ SEM of relative RNA expression normalized against the relevant reference gene, 18sRNA (for CRH-R1) or -actin (for PGHS2). *, P ...
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Expression of corticotrophin releasing hormone receptor subtypes in human myometrium and cloning of the promoter region for the CRH receptors type 2
... There are potential cis-acting elements SP1, AP1, AP2, GATA, CRE-BP and MyoD in the 5'-flanking sequence.The CRH-R2 5'-flanking housekeeping including its has of a gene promoter many cha[r] ...
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Important differences in nitric oxide synthase activity and predominant isoform in reproductive tissues from human and rat
... pregnant human myometrium showed a significantly lower NOS activity in both fractions from pregnant myo- metrium than from the non-pregnant ...during human pregnancy have not provided any concrete ...
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Contractile properties of multiple pregnancy myometrium
... predominant role in the human myometrium. BKca channels are sensitive to voltage as well as calcium. They have a basic structure of S1-S6 transmembrane domains plus an additional four hydrophobic domains ...
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Investigating the role of hydrogen sulfide in the myometrium
... the myometrium change with age? Spontaneous contractions of non-pregnant human myometrium irrespective of menopausal state or presence of endometriosis was examined in relation to ...
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DNA fragmentation factors 40 and 45 (DFF40/DFF45) and B-cell lymphoma 2 (Bcl-2) protein are underexpressed in uterine leiomyosarcomas and may predict survival
... normal human myometrium, but also with cases of leiomyomas and myometrium from corresponding ...control myometrium were seen in DFF40, DFF45, and Bcl-2 expression; these observations agree ...
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Expression of ATP-sensitive potassium channels in human pregnant myometrium
... Human myometrium undergoes dramatic physiological and biochemical changes during pregnancy and parturi- ...tion. Myometrium remains in a relatively quiescent state during most time of pregnancy, but ...
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