human osteoblasts
Betaine promotes cell differentiation of human osteoblasts in primary culture
... The present results are in line with our previous study showing that BET acts early in the process of myogen- esis to determine cell fate [6]. We there used an in vitro murine model of myoblasts that, upon BET, exhibited ...
14
Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis
... and an average expression measure for each time point used to identify alterations in gene expression. RMA nor- malised data was found to be comparable across the time series with the computed average expression aligning ...
12
Human osteoblasts exhibit sexual dimorphism in their response to estrogen on microstructured titanium surfaces
... in human donors could impact the consistency of observations, making it imperative to test multiple do- nors when using primary human osteoblasts for experi- ...male human osteoblasts ...
10
Sequential activation of the AKT pathway in human osteoblasts treated with Oscarvit: a bioactive product with positive effect both on skeletal pain and mineralization in osteoblasts
... specimens. Human osteoblasts are com- monly used to analyze bone metabolism, osteogenesis and focal bone erosion in patients with joint ...in osteoblasts [17, ...
9
Human osteoblasts in vitro secrete tissue inhibitor of metalloproteinases and gelatinase but not interstitial collagenase as major cellular products
... that human osteoblasts do not initiate and direct the cleavage of osteoid collagen on the bone surface, but may participate in the preparation of the bone surface for osteoclast attachment by removal of ...
10
NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts
... In humans, the microtubule-associated protein light chain 3 (LC3) is generated as a precursor immediately transformed into its cytosolic unconjugated form, LC3-I, which is then conjugated to the membrane phospholipid ...
16
Genetically transforming human osteoblasts to sarcoma: development of an osteosarcoma model
... mMSCs, do not transform when cultured in vitro for extensive periods of time, possibly secondary to increased genetic stability [34]. Multiple studies have demonstrated the development of osteosarcoma from the ...
11
Evaluation of Biofield Energy Treated Vitamin D3 in Human Osteoblasts Cells
... active osteoblasts synthesize and extrude collagen, which plays an important role in the formation of bone extracellular matrix by providing strength and ...
9
Insulin like growth factor system abnormalities in hepatitis C associated osteosclerosis Potential insights into increasing bone mass in adults
... by human osteoblasts and that in an extracellular matrix–rich environment, the IGF-II/IGFBP-2 complex was as effective as IGF-II alone in stimulating human os- teoblast ...
10
Transforming growth factor β1 inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy?
... primary human osteoblasts as the major target for BMP therapy, the effects of the chosen HDAC inhibitor on bone resorption by osteoclasts should be also ...
11
Human oral cells’ response to different endodontic restorative materials: an in vitro study
... The most ideal healing outcome after filling the resected root canal or the perforation would be reformation of a normal attachment apparatus with healthy bone, peri- odontal ligament, and cementum [27]. Hence, the ...
9
Increased bone formation and decreased osteocalcin expression induced by reduced Twist dosage in Saethre Chotzen syndrome
... in human calvaria ...to osteoblasts that express ...in human mutant cal- varia osteoblasts alters the expression of the osteoblast marker gene OC in addition to promoting osteogene- ...M-Tw ...
10
The influence of tantalum on human cell lineages important for healing in soft-tissue reattachment surgery: an in-vitro analysis
... of human fibroblasts with no quantifiable negative effects seen on fibroblast behaviour after 28 days ...of human osteoblasts or human mesenchymal stem ...
6
Size-dependent Effects of Gold Nanoparticles on Osteogenic Differentiation of Human Periodontal Ligament Progenitor Cells
... Gold nanoparticles (AuNPs) have been reported to promote osteogenic differentiation of mesenchymal stem cells and osteoblasts, but little is known about their effects on human periodontal ligament ...
11
Apoptotic and Autophagic modulation by nicotine
... Hill, MM, Adrain, C, Duriez, PJ, Creagh, EM, Martin, SJ. (2004). Analysis of the composition, assembly kinetics and activity of native Apaf‐1 apoptosomes. EMBO J., 23(10):2134-2145. Jayakiran, M. (2015). ...
11
Vesicular trafficking in osteoblasts
... which osteoblasts achieve regulated and directed bone matrix p ro tein secretion are not clearly ...enabling osteoblasts to deposit matrix as p art of a concerted effort, maximising their ...
327
Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4 hydroxynonenal
... Osteoblasts were incubated in fresh medium containing 0.5% FBS/HAMF12/DMEM in the presence of increasing concen- trations of HNE (0 to 20 μ M) for 24 hours or in the presence of 20 μM of HNE for increasing periods ...
14
Effects of platelet rich plasma (PRP) on human gingival fibroblast, osteoblast and periodontal ligament cell behaviour
... and osteoblasts activity in vitro ...and osteoblasts including increased cell migration, proliferation or collagen synthesis, these marked increases were less pronounced and did not seem to contribute to ...
10
CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer
... con fi rmed by an independent pool of siRNAs (Supplementary Figure 4E). Signi fi cant rescue of the effects of shRNA knockdown could be again achieved by the non-targetable CRIPTO expression construct solely in ...
11
Tridax procumbens flavonoids promote osteoblast differentiation and bone formation
... significant upregulation of osterix, Bmp-2, Bmp-4 and Bmp-7 compared to control group (Figs. 1h, 2). Osteo- blasts play a crucial role in the bone formation, differenti- ating from mesenchymal stem cells is regulated by ...
8