human osteoclast-like cells
Estrogen’s bone protective effects may involve differential IL 1 receptor regulation in human osteoclast like cells
... hOCL cells correlate with the age and gender of the bone marrow ...hOCL cells derived from bone marrow mononuclear preparations of 22 different donors over the age of 40, and the results were expressed as ...
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Osteoclast like cells form in long term human bone marrow but not in peripheral blood cultures
... mononuclear cells contain precursors for ...mononuclear cells from feline, baboon, and human marrow form osteoclast-like cells in long term ...these cells is increased in ...
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Recombinant human transforming growth factor alpha stimulates the formation of osteoclast like cells in long term human marrow cultures
... increases osteoclast activity is unknown. We used a human marrow culture system that forms osteoclast-like multinucleated cells (MNCs) to determine the effects of recombinant ...
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Case Report Mammary carcinoma with osteoclast-like giant cells: a case report
... with osteoclast-like giant cells is rare, and comprises less that 2% of breast carci- noma ...prominent osteoclast like giant cell compo- ...the osteoclast-like giant ...
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Bone marrow derived osteoclast like cells from a patient with craniometaphyseal dysplasia lack expression of osteoclast reactive vacuolar proton pump
... Using osteoclast-like cells formed from patient bone marrow cells, we investigated the pathophysiology of CMD in a 3- yr-old ...marrow cells from the patient differentiated into ...
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Prostaglandin G/H synthase 2 is required for maximal formation of osteoclast like cells in culture
... tures is due to increased GM-CSF expression. Several previous studies have found that prostaglandins or cAMP analogues downregulate the expression of GM- CSF in marrow stromal cells and lymphocytes (53–55). ...
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Multifocal invasive ductal breast cancer with osteoclast like giant cells: a case report
... Ventana), human epidermal growth factor recep- tor 2 (HER2) (Roche Ventana) and Ki-67 antigen (Roche Ventana) using the ultraView ™ Universal Alkaline Phos- phatase Red Detection Kit (Roche Ventana) on the Roche ...
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Osteoclast independent bone resorption by fibroblast like cells
... of human macrophages and osteoclasts in the ...the human nature of cells invading the coimplanted bone, and no murine osteoclasts were observed at sites of bone resorption in the SCID ...
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Inhibition of osteoclast like cell formation by bisphosphonates in long term cultures of human bone marrow
... these cells with the same relative potencies as they inhibit bone resorption in ...the osteoclast-like ...multinucleated cells expressing an osteoclast antigen, thus suggesting a degree ...
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Downregulation of calcitonin receptor mRNA expression by calcitonin during human osteoclast like cell differentiation
... osteoclasts, and used reverse transcriptase (RT)-PCR to assess expression of CTR mRNA in both committed mononuclear precursors and MNC. The PCR fragment produced was cloned and sequenced to confirm that it was derived ...
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Flavonoids isolated from Tridax procumbens (TPF) inhibit osteoclasts differentiation and bone resorption
... are produced by osteoblasts or stromal cells [2]. Osteo- clasts, which are essential in bone homeostasis, play a key role in the development of osteoporosis, inflamma- tory arthritis, and rheumatoid arthritis ...
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Case Report Giant cell rich osteosarcoma of the mandible with abundant spindle cells and osteoclast-like giant cells mimicking malignancy in giant cell tumor
... tumor cells may be: plasmacytoid, fusiform, ovoid, small round cells, clear cells, mono-or multinucleated giant cells, or, spindle ...spindle cells with marked atypia and numerous ...
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Impact of Bisphosphonates on the Osteoclast Cells of Osteogenesis Imperfecta Patients
... mononuclear cells (PBMC) was performed. Mononuclear cells were stained with monoclonal antihuman RANK- PE (9A725, Thermofisher, scientific) and caspase-3 NucView 488 ...antibodies. Cells were ...
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Osteoclast-like Cells in Early Zebrafish Embryos
... in cells of zebrafish embryos of 1-5 days post ...the cells scattered sparsely in the ...expressing cells were located around the developing cartilage elements, in the parachondral ...expressing ...
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Case Report Well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland in children: a case report and literature review
... tumor cells and contain- ing 2 to more than 30 nuclear, the osteoclast- like giant cells may be very ...tumor cells. The above has shown that the osteoclast-like giant ...
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A male case of an undifferentiated carcinoma with osteoclast like giant cells originating in an indeterminate mucin producing cystic neoplasm of the pancreas A case report and review of the literature
... We report a rare male case of an undifferentiated carcinoma with osteoclast-like giant cells originating in an indeterminate mucin-producing cystic neoplasm of the pancreas. A 59-year-old Japanese ...
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Case Report Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells: a rare case report and review of the literature
... non-neoplastic osteoclast-like giant cells and pleomorphic neoplastic mononuclear ...giant cells are non-neoplastic in nature and of histiocytic ...giant cells is the histological ...
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Metabolic properties of the osteoclast
... precursor cells using MCSF and RANKL and exposed to the acidic conditions required for activation [51,7] (Fig ...activated osteoclast in vitro can resorb an estimated quantity of mineralised matrix ...
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Signaling crosstalk between RANKL and interferons in osteoclast differentiation
... The induction of the IFN- α / β gene in virally infected cells requires two IRF transcription factors, IRF-3 and IRF-7 [31]. In the case of IFN- β , induction has also been known to depend on NF-κB (which is also ...
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Invasive ductal carcinoma of the breast with osteoclast like giant cells and clear cell features: a case report of a novel finding and review of the literature
... Clear cells are a rare histologic finding in a primary breast cancer and can be seen in several tumor ...neoplastic cells contain clear cytoplasm filled with glycogen [10], reflecting the variability of ...
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