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Human Parechovirus

Epidemiology of Sepsis-like Illness in Young Infants Major Role of Enterovirus and Human Parechovirus

Epidemiology of Sepsis-like Illness in Young Infants Major Role of Enterovirus and Human Parechovirus

... Epidemiology of Sepsis-like Illness in Young Infants: Major Role of Enterovirus and Human.. Parechovirus.[r] ...

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Arginine-Glycine-Aspartic Acid Motif Is Critical for Human Parechovirus 1 Entry

Arginine-Glycine-Aspartic Acid Motif Is Critical for Human Parechovirus 1 Entry

... Human parechovirus 1 (HPeV1) is a common pathogen that usually causes mild disease, typically in children (21, 43, ...the human parechovirus species of the recently recognized ...

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Human Parechovirus as a Cause of Isolated Pediatric Acute Liver Failure

Human Parechovirus as a Cause of Isolated Pediatric Acute Liver Failure

... Among infants, almost half of acute liver failure cases are classified as indeterminate, whereas only a small number of cases show a documented viral infection. We present the first reported case of isolated acute ...

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Human Parechovirus 1 Utilizes Integrins αvβ3 and αvβ1 as Receptors

Human Parechovirus 1 Utilizes Integrins αvβ3 and αvβ1 as Receptors

... Human parechovirus 1 (HPEV1), a representative of an independent picornavirus genus (19, 24) previously classified as echovirus 22, is a small, nonenveloped, single-stranded RNA ...

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In Vivo and In Vitro Identification of Structural and Sequence Elements of the Human Parechovirus 5′ Untranslated Region Required for Internal Initiation

In Vivo and In Vitro Identification of Structural and Sequence Elements of the Human Parechovirus 5′ Untranslated Region Required for Internal Initiation

... important human and animal ...genus, Parechovirus, and renamed human parechovirus types 1 and 2 (HPeV1 and -2), respectively ...(68). Human parechovi- ruses had previously been shown to ...

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The Structure of Human Parechovirus 1 Reveals an Association of the RNA Genome with the Capsid

The Structure of Human Parechovirus 1 Reveals an Association of the RNA Genome with the Capsid

... are human pathogens that cause diseases ranging from gastrointestinal disorders to ...picornaviruses, parechovirus capsids are composed of only three subunits: VP0, VP1, and ...a human ...

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Human Memory B Cells Producing Potent Cross-Neutralizing Antibodies against Human Parechovirus: Implications for Prevalence, Treatment, and Diagnosis

Human Memory B Cells Producing Potent Cross-Neutralizing Antibodies against Human Parechovirus: Implications for Prevalence, Treatment, and Diagnosis

... important human and animal ...genus Parechovirus consists of two species, Ljungan virus and Human parechovirus (HPeV), which at present contains 16 recognized ge- notypes ...the human ...

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A 2.8-Angstrom-Resolution Cryo-Electron Microscopy Structure of Human Parechovirus 3 in Complex with Fab from a Neutralizing Antibody

A 2.8-Angstrom-Resolution Cryo-Electron Microscopy Structure of Human Parechovirus 3 in Complex with Fab from a Neutralizing Antibody

... Exact knowledge of the structural, antigenic, and immunogenic features of HPeV3 is essential for understanding host-pathogen interactions and viral pathogenesis mech- anisms and for finding potential cures for infection ...

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Successful IVIG Treatment of Human Parechovirus-Associated Dilated Cardiomyopathy in an Infant

Successful IVIG Treatment of Human Parechovirus-Associated Dilated Cardiomyopathy in an Infant

... of human enterovirus and human parechovirus (HPeV) genotypes from clini- cal stool samples: polymerase chain re- action and direct molecular typing, culture characteristics, and ...

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Interaction of αVβ3 and αVβ6 Integrins with Human Parechovirus 1

Interaction of αVβ3 and αVβ6 Integrins with Human Parechovirus 1

... VP4). Human parechovirus 1 (HPEV1) is a member of the Parechovirus genus of the Picornaviridae family (38, ...man parechovirus types and 14 described types (4, 19, 24, 30, 38, 39, 51, 58, ...

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Viral infections in young infants : epidemiologic and diagnostic aspects of ToRCH, enterovirus and human parechovirus

Viral infections in young infants : epidemiologic and diagnostic aspects of ToRCH, enterovirus and human parechovirus

... The aim of the first part of this thesis (part A) was to investigate the yield of performing diagnostic tests for ‘ToRCH’ infections in newborn infants with lenticulostriate vasculopathy (LSV) or small for gestational ...

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Severe epidemic myalgia with an elevated level of serum interleukin 6 caused by human parechovirus type 3: a case report and brief review of the literature

Severe epidemic myalgia with an elevated level of serum interleukin 6 caused by human parechovirus type 3: a case report and brief review of the literature

... Human parechovirus type 3 (HPeV-3) was first reported in 2004 [1] and has since been identified to cause cold-like symptoms, diarrhea, or severe infections such as meningitis and sepsis-like disease in ...

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Entry of Human Parechovirus 1

Entry of Human Parechovirus 1

... Human parechovirus 1 (HPEV-1) and HPEV-2 were re- cently reclassified in the new Parechovirus genus on the basis of their exceptional molecular and biological properties among picornaviruses ...

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Analysis of a New Human Parechovirus Allows the Definition of Parechovirus Types and the Identification of RNA Structural Domains

Analysis of a New Human Parechovirus Allows the Definition of Parechovirus Types and the Identification of RNA Structural Domains

... because the cleavage of VP0 to VP4 and VP2 seen in other picornaviruses does not occur (43). In addition, in common with that of members of another picornavirus genus Kobuvirus, the 2A protein is of an unusual form, ...

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Identification of a contemporary human parechovirus type 1 by VIDISCA and characterisation of its full genome

Identification of a contemporary human parechovirus type 1 by VIDISCA and characterisation of its full genome

... a human parechovirus type ...species Human Parechovirus (HPeV) cause symptoms of common cold and enteritis, but also encephalitis, myo- carditis, and other conditions ...

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ATP Hydrolysis and AMP Kinase Activities of Nonstructural Protein 2C of Human Parechovirus 1

ATP Hydrolysis and AMP Kinase Activities of Nonstructural Protein 2C of Human Parechovirus 1

... Human parechovirus 1 (HPEV1) is a human pathogen as- sociated with gastrointestinal and respiratory symptoms and occasionally with infections of the central nervous system ...the Parechovirus ...

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Prevalence of Human Parechovirus in The Netherlands in 2000 to 2007

Prevalence of Human Parechovirus in The Netherlands in 2000 to 2007

... Human parechovirus 1 (HPeV1) and HPeV2, initially known as echovirus 22 (EV22) and EV23, were first isolated in the summer of 1956 in Japan from stool specimens of children suffering from diarrhea ...other ...

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Development and Assay of RNA Transcripts of Enterovirus Species A to D, Rhinovirus Species A to C, and Human Parechovirus: Assessment of Assay Sensitivity and Specificity of Real Time Screening and Typing Methods

Development and Assay of RNA Transcripts of Enterovirus Species A to D, Rhinovirus Species A to C, and Human Parechovirus: Assessment of Assay Sensitivity and Specificity of Real Time Screening and Typing Methods

... D), human rhinoviruses (HRVs; species A to C), and human parechovirus (HPeV) in a multicenter assay evaluation using a series of full-length prequantified RNA ...

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Optimization of a Combined Human Parechovirus Enterovirus Real Time Reverse Transcription PCR Assay and Evaluation of a New Parechovirus 3 Specific Assay for Cerebrospinal Fluid Specimen Testing

Optimization of a Combined Human Parechovirus Enterovirus Real Time Reverse Transcription PCR Assay and Evaluation of a New Parechovirus 3 Specific Assay for Cerebrospinal Fluid Specimen Testing

... H uman parechoviruses (HPeVs) were previously classified in the Enterovirus genus but on the basis of distinct genetic and biological properties have been reclassified into a new genus, Parechovirus, within the ...

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Epidemiology of human parechovirus, Aichi virus and salivirus in fecal samples from hospitalized children with gastroenteritis in Hong Kong

Epidemiology of human parechovirus, Aichi virus and salivirus in fecal samples from hospitalized children with gastroenteritis in Hong Kong

... 1, human bocavirus (HBoV) in 2, AiV in 1, SalV in 1, Salmonella enterica serotypes in 5, Campylobacter jejuni in 1, Staphylococcus aureus in 7, enteropathogenic Escheri- chia coli in 1, and Aeromonas species in ...

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