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Human small airway epithelial cell

Low concentrations of clarithromycin upregulate cellular antioxidant enzymes and phosphorylation of extracellular signal-regulated kinase in human small airway epithelial cells

Low concentrations of clarithromycin upregulate cellular antioxidant enzymes and phosphorylation of extracellular signal-regulated kinase in human small airway epithelial cells

... SABM: Small airway basal medium; SAEC: Human small airway epithelial cell; SAGM: Small airway growth medium; SOD: Superoxide dismutase; WST-8: ...

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High temperature requirement A3 (HTRA3) expression predicts postoperative recurrence and survival in patients with non- small-cell lung cancer

High temperature requirement A3 (HTRA3) expression predicts postoperative recurrence and survival in patients with non- small-cell lung cancer

... normal human small airway epithelial cells (SAECs) than in lung cancer cell lines, whereas the expression of the short isoform (HTRA3-S) did not differ significantly between normal and ...

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Evaluation of cytotoxic, genotoxic and inflammatory responses of nanoparticles from photocopiers in three human cell lines

Evaluation of cytotoxic, genotoxic and inflammatory responses of nanoparticles from photocopiers in three human cell lines

... pect) cell type dependent, with the monocytic THP-1 cell line being more sensitive to NP exposure than the two pri- mary respiratory epithelial ...THP-1 cell type were about an order of ...

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Neoplastic Transformation of Human Small Airway Epithelial Cells Induced by Arsenic

Neoplastic Transformation of Human Small Airway Epithelial Cells Induced by Arsenic

... in cell adhesion char- acteristics may imply change in integrin function, which plays an essential role in cell attachment, we examined the ex- pression of various integrin receptor functions in control and ...

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4-Hydroxynonenal regulates mitochondrial function in human small airway epithelial cells

4-Hydroxynonenal regulates mitochondrial function in human small airway epithelial cells

... synthesis, control of electron flow, and production of reducing equivalents [9, 40]. Mitochondrial reserve capacity is considered to be exceptionally important when responding to stress, acting as an additional mechanism ...

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One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation

One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation

... non-small cell lung cancer (NSCLC) that is thought to originate from epi- thelial cells of the small airway or the alveolus ...that human lung adenocarcinomas fre- quently harbor ...

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Nitric oxide gas phase release in human small airway epithelial cells

Nitric oxide gas phase release in human small airway epithelial cells

... primary human small airway epi- thelial cells (SAECs) would produce detectable NO gas phase release following stimulation by IL-13 and cytomix (IL-1β, TNF-α, and ...carcinoma cell line, model ...

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Epithelial disruption: a new paradigm enabling human airway stem cell transplantation

Epithelial disruption: a new paradigm enabling human airway stem cell transplantation

... considerable cell debris present ...d). Small amounts of cellular debris were still present 24 h after PDOC ...hABC-Luc cell delivery conducted 2 h after ...

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Regional heterogeneity in response of airway epithelial cells to cigarette smoke

Regional heterogeneity in response of airway epithelial cells to cigarette smoke

... each cell type ob- served under non-differentiating conditions could be affected by contamination with different cell ...to human air- ...between small-airway cells and other cells will ...

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Cell-to-Cell Contact and Nectin-4 Govern Spread of Measles Virus from Primary Human Myeloid Cells to Primary Human Airway Epithelial Cells

Cell-to-Cell Contact and Nectin-4 Govern Spread of Measles Virus from Primary Human Myeloid Cells to Primary Human Airway Epithelial Cells

... pulmonary epithelial cells are poorly ...from human donors and generated primary myeloid cells, specifically, monocyte-derived macrophages (MDMs) and dendritic cells ...well-differentiated airway ...

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Allergen induced IL 9 directly stimulates mucin transcription in respiratory epithelial cells

Allergen induced IL 9 directly stimulates mucin transcription in respiratory epithelial cells

... in human airway epithelium and NCI- H292 ...Pseudostratified epithelial cells had the greatest degree of immunoreactivity, but staining was also associated with the endothelium of small blood ...

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The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium

The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium

... cated times (5–60 min). In separate experiments, NCI- H292 cells were initially pretreated with 10 μM H89 (PKA inhibitor; 30 min) or 5 μM U0126 (MEK inhibitor; 120 min) before treatment of the cells with A68930 (1 μM; 20 ...

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Effect of vitamin D3 on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial

Effect of vitamin D3 on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial

... that airway epithelial cells exposed to CSE and supplemented with 25(OH)D 3 had a smaller increase in CAMP gene expression compared with unexposed cells (figure ...synthetic human LL-37 coincubated ...

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pats.200805-041hr.pdf

pats.200805-041hr.pdf

... stem/progenitor cell behavior in the setting of airway injury, repair, and ...stem/progenitor cell properties through cellcell contact with supporting cells, paracrine and endocrine ...

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Culturing the Unculturable: Human Coronavirus HKU1 Infects, Replicates, and Produces Progeny Virions in Human Ciliated Airway Epithelial Cell Cultures

Culturing the Unculturable: Human Coronavirus HKU1 Infects, Replicates, and Produces Progeny Virions in Human Ciliated Airway Epithelial Cell Cultures

... into permissive cells were used. We have previously used this approach with HAE to successfully ablate SARS-CoV infec- tion using antibodies to block virus binding to angiotensin converting enzyme 2 (ACE2) (45). In the ...

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Dimeric procyanidins as modulators of airway inflammation in the context of allergic asthma : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Human Physiology at Massey University, Manawatū, Pal

Dimeric procyanidins as modulators of airway inflammation in the context of allergic asthma : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Human Physiology at Massey University, Manawatū, Palmerston North, New Zealand

... 13 proanthocyanidin intake for adults in the US has been reported as 95 mg/day [16]. The major food sources of proanthocyanidins in the US are tea, legumes, and wine. Tea is the primary source of monomers and dimers, ...

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TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death

TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death

... the human immunology array in comparisons of samples with ricin or TRAIL or ricin-plus-TRAIL treatments to medium control samples (data not ...the human immunol- ogy nCounter array ...

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Receptor Binding Profiles of Avian Influenza Virus Hemagglutinin Subtypes on Human Cells as a Predictor of Pandemic Potential

Receptor Binding Profiles of Avian Influenza Virus Hemagglutinin Subtypes on Human Cells as a Predictor of Pandemic Potential

... a human-tropic virus emerging from an avian reservoir may be greater than previously ...vivo human tracheal sections. (A to H) Ex vivo human trachea sections were probed with HA-Fc ...protein-bound ...

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Analysis of the proteome of human airway epithelial secretions

Analysis of the proteome of human airway epithelial secretions

... by human and animal airway epithe- lial cell cultures ...to cell signaling to forming protective physical barriers against chemical or biological damage ...

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Airway epithelial cell tolerance to Pseudomonas aeruginosa

Airway epithelial cell tolerance to Pseudomonas aeruginosa

... enhance epithelial cell sensitivity to pathogen ...Decreased cell surface TLR4 protein [23] was associated with tolerance, but tolerance could not be attributed solely to receptor loss, since cells ...

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