Human Subjects
Studies of liver insulin receptors in non obese and obese human subjects
... reported in rat liver. Sulfhydryl reduction demonstrated a major sub-unit of 125,000 and a minor component of 40,000-45,000 in both groups. These results indicate a close similarity between the hepatic insulin receptor ...
9
Welfare versus Autonomy in Human Subjects Research
... in human subjects ...drugs, subjects are randomly assigned to receive either stand- ard treatment or experimental treatment (there is no placebo arm, absent unusual ...
44
Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects
... in human appetite regula- tion and weight control is ...in human subjects that fasting for 24–52 h produced dramatic decreases in serum leptin concentrations ( ...
8
Two kinds of rule regulating human subjects research
... Alan Wertheimer argues that before we promulgate some rule regarding the conduct of research on human subjects we ethically ought to consider the consequences of the rule being followed. This ethical ...
7
RENAL CLEARANCE OF EIGHTEEN INDIVIDUAL AMINO ACIDS IN HUMAN SUBJECTS
... The renal clearances of 18 individual amino acids have been studied in three normal human subjects by the simultaneous measurement of inulin and amino acid excretion during periods of fa[r] ...
10
A Review on Experimental Assessments of Pain Threshold in Healthy Human Subjects
... These instruments provide constant current high voltage pulses of brief duration for percutaneous stimulation dur- ing investigation of electrical activity in nerve and mus- cle. The output current is more often ...
6
THE INFLUENCE OF DIETARY PROTEIN ON PLASMA LIPIDS IN HUMAN SUBJECTS
... The results of the present study, demonstrating a lack of effect of dietary protein on the plasma cholesterol levels of human subjects, are in agreement with the report of Keys and Ander[r] ...
7
Compensation in Moral Science: Protecting Participants in Human Subjects Research
... subcommittee of international experts in bioethics and biomedical research. This subcommittee, the International Research Panel, published its proceedings in 2011, Research Across Borders: Proceedings of the ...
18
Capacity of human subjects to utilize keto analogues of valine and phenylalanine
... adult human subjects were maintained for 7 days (period I) on a protein-free formula diet containing the minimum daily requirements of the eight essential amino acids plus 40 g ...three subjects were ...
8
Informed Consent in Human Subjects Research
... of human subjects research including; diagnostic, therapeutic, interventional, social and behavioral studies, and for research conducted domestically or ...
22
Human subjects requirements and economic education researchers
... Risk-averse university officials, observing lawsuits filed against universities for human subjects violations in medical experiments, may "overreact when confronted with human subject co[r] ...
14
Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects
... The functioning of mitochondria as a DAMP in the activation of the NLRP3 inflammasome has been well established and appears to be orches- trated via the extrusion of numerous components of the mitochondria, including ...
10
Diurnal Variation in the Responsiveness of Human Subjects to Human Growth Hormone
... of human subjects to the anabolic effects of human growth hormone (HGH) administered at 8 ...The subjects were of two groups: (a) seven GH- deficient children, of whom three were deficient in ...
8
Conversion of Thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects
... When oral medication was enriched with 'I-labeled T4 for 8 or more days, labeled T3 and tetraiodothyroacetic acid Tetrac or TA4 were found in the serum to the extent of approximately 2-5[r] ...
11
INFLUENCE OF SODIUM INTAKE ON EXCHANGEABLE SODIUM IN NORMAL HUMAN SUBJECTS
... Body weight; sodium intake, output, and serum concentration; serum and body Na22 values; and exchangeable sodium determinations in Subject J.C... Urine Na output.[r] ...
13
THE QUANTITATIVE DETERMINATION OF IRON KINETICS AND HEMOGLOBIN SYNTHESIS IN HUMAN SUBJECTS
... This is to be expected, since radioiron is fixed at all stages of erythron maturation and the RCVf - RCVoMCHC/100 g/day Hb half-time for transfer of iron from the erythropoietic labile p[r] ...
31
COMPARATIVE STUDIES ON THE TURNOVER OF SERUM ALBUMIN IN NORMAL HUMAN SUBJECTS
... LATIONSHIP BETWEEN SPECIFIC ACTIVITY OF PLASMA PROTEIN AND TIME IN NORMAL SUBJECTS GIVEN HEAVILY IODINATED AND LIGHTLY IODINATED HUMAN SERUM ALBUMIN LIGHTLY AND VERY LIGHTLY IODINATED PR[r] ...
13
Dietary induced subclinical vitamin K deficiency in normal human subjects
... The PT and APTT remained constant throughout the study period and did not increase in response to the vitamin K depletion even though plasma levels of vitamin K, fell below the normal ra[r] ...
9
Effects of lovastatin and dietary cholesterol on sterol homeostasis in healthy human subjects
... In addition to lowering serum LDL cholesterol, lovastatin significantly lowered biliary secretion of cholesterol, fecal output of endogenous neutral sterols, cholesterol balance, and sys[r] ...
9
Instructions for Registering and Completing Initial Human Subjects Training Certification
... 12. The Office for Human Subject Protection (OHSP) will be notified automatically that you completed the course. Therefore, you do not need to provide a copy of your completion report to OHSP. Within 1-2 business ...
5